Distinct Properties of Glycine Receptor β+/α− Interface

Function of hyperekplexia-causing α1R271Q/L glycine receptors is restored by shifting the affected residue out of the allosteric signalling pathway

(2011) Qiang Shan et al.   BRITISH JOURNAL OF PHARMACOLOGY

A novel GABAA receptor pharmacology: drugs interacting with the α+β- interface

(2011) Werner Sieghart et al.   BRITISH JOURNAL OF PHARMACOLOGY

Molecular Determinants of Ivermectin Sensitivity at the Glycine Receptor Chloride Channel

(2011) Timothy Lynagh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The GABAA Receptor  + - Interface: A Novel Target for Subtype Selective Drugs

(2011) J. Ramerstorfer et al.   JOURNAL OF NEUROSCIENCE

Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

β Subunit M2–M3 Loop Conformational Changes Are Uncoupled from α1 β Glycine Receptor Channel Gating: Implications for Human Hereditary Hyperekplexia

(2011) Qiang Shan et al.   PLoS One

Chimera construction using multiple-template-based sequential PCRs

(2010) Qiang Shan et al.   JOURNAL OF NEUROSCIENCE METHODS

The structural basis of function in Cys-loop receptors

(2010) Andrew J. Thompson et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Binding, activation and modulation of Cys-loop receptors

(2010) Paul S. Miller et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mapping of Disulfide Bonds within the Amino-terminal Extracellular Domain of the Inhibitory Glycine Receptor

(2009) Nicolas Vogel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ligand-specific Conformational Changes in the α1 Glycine Receptor Ligand-binding Domain

(2009) Stephan A. Pless et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Magnitude of a Conformational Change in the Glycine Receptor β1-β2 Loop Is Correlated with Agonist Efficacy

(2009) Stephan A. Pless et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding to Gating Transduction in Nicotinic Receptors: Cys-Loop Energetically Couples to Pre-M1 and M2-M3 Regions

(2009) W. Y. Lee et al.   JOURNAL OF NEUROSCIENCE

Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

(2009) Antoine Taly et al.   NATURE REVIEWS DRUG DISCOVERY

ILLUMINATING THE STRUCTURE AND FUNCTION OF CYS-LOOP RECEPTORS

(2008) Stephan A Pless et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

Native glycine receptor subtypes and their physiological roles

(2008) Joseph W. Lynch   NEUROPHARMACOLOGY

The 5-HT3 receptor – the relationship between structure and function

(2008) Nicholas M. Barnes et al.   NEUROPHARMACOLOGY

GABAA receptors: Subtypes provide diversity of function and pharmacology

(2008) Richard W. Olsen et al.   NEUROPHARMACOLOGY

International Union of Pharmacology. LXX. Subtypes of  -Aminobutyric AcidA Receptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update

(2008) R. W. Olsen et al.   PHARMACOLOGICAL REVIEWS