A Network of Ubiquitin Ligases Is Important for the Dynamics of Misfolded Protein Aggregates in Yeast

The [RNQ+] prion: A model of both functional and pathological amyloid

(2012) Kevin C. Stein et al.   Prion

Quality control and fate determination of Hsp90 client proteins

(2011) Maria A. Theodoraki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

UBR1 promotes protein kinase quality control and sensitizes cells to Hsp90 inhibition

(2011) Rasheda Sultana et al.   EXPERIMENTAL CELL RESEARCH

Hsp42 is required for sequestration of protein aggregates into deposition sites inSaccharomyces cerevisiae

(2011) Sebastian Specht et al.   JOURNAL OF CELL BIOLOGY

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

Hul5 HECT ubiquitin ligase plays a major role in the ubiquitylation and turnover of cytosolic misfolded proteins

(2011) Nancy N. Fang et al.   NATURE CELL BIOLOGY

Amyloid in neurodegenerative diseases: Friend or foe?

(2011) Katie J. Wolfe et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae

(2011) Undine Kruegel et al.   PLoS Genetics

ErbB2 Trafficking and Degradation Associated with K48 and K63 Polyubiquitination

(2010) Corina Marx et al.   CANCER RESEARCH

The Tumor Suppressor Protein Menin Inhibits AKT Activation by Regulating Its Cellular Localization

(2010) Yan Wang et al.   CANCER RESEARCH

A Nucleus-based Quality Control Mechanism for Cytosolic Proteins

(2010) Rupali Prasad et al.   MOLECULAR BIOLOGY OF THE CELL

Ubr1 and Ubr2 Function in a Quality Control Pathway for Degradation of Unfolded Cytosolic Proteins

(2010) Nadinath B. Nillegoda et al.   MOLECULAR BIOLOGY OF THE CELL

Role of a ribosome-associated E3 ubiquitin ligase in protein quality control

(2010) Mario H. Bengtson et al.   NATURE

The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases

(2010) Cheol-Sang Hwang et al.   NATURE CELL BIOLOGY

Cellular strategies for controlling protein aggregation

(2010) Jens Tyedmers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1

(2009) J. W. Heck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration

(2009) J. Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase

(2009) E. S. Ehrlich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1

(2008) Frederik Eisele et al.   FEBS LETTERS

Degradation of a Cytosolic Protein Requires Endoplasmic Reticulum-associated Degradation Machinery

(2008) Meredith Boyle Metzger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Farnesylation of Ydj1 Is Required for In Vivo Interaction with Hsp90 Client Proteins

(2008) Gary A. Flom et al.   MOLECULAR BIOLOGY OF THE CELL

Analysis of Quality Control Substrates in Distinct Cellular Compartments Reveals a Unique Role for Rpn4p in Tolerating Misfolded Membrane Proteins

(2008) Meredith Boyle Metzger et al.   MOLECULAR BIOLOGY OF THE CELL

Misfolded proteins partition between two distinct quality control compartments

(2008) Daniel Kaganovich et al.   NATURE

One step at a time: endoplasmic reticulum-associated degradation

(2008) Shruthi S. Vembar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY