Using Hydrogen/Deuterium Exchange Mass Spectrometry to Define the Specific Interactions of the Phospholipase A2Superfamily with Lipid Substrates, Inhibitors, and Membranes

Probing protein interactions with hydrogen/deuterium exchange and mass spectrometry—A review

(2012) Andrew J. Percy et al.   ANALYTICA CHIMICA ACTA

Structure/Function Relationships of Adipose Phospholipase A2Containing a Cys-His-His Catalytic Triad

(2012) Xiao-Yan Pang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of specific interactions of Lp-PLA2with HDL revealed by hydrogen deuterium exchange mass spectrometry

(2012) Jian Cao et al.   JOURNAL OF LIPID RESEARCH

Dynamics of a bacterial multidrug ABC transporter in the inward- and outward-facing conformations

(2012) S. Mehmood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein dynamics viewed by hydrogen exchange

(2012) John J. Skinner et al.   PROTEIN SCIENCE

Lipoprotein-Associated Phospholipase A2Interacts with Phospholipid Vesicles via a Surface-Disposed Hydrophobic α-Helix

(2011) Jian Cao et al.   BIOCHEMISTRY

Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention

(2011) Edward A. Dennis et al.   CHEMICAL REVIEWS

Quantitative Assessment of Protein Structural Models by Comparison of H/D Exchange MS Data with Exchange Behavior Accurately Predicted by DXCOREX

(2011) Tong Liu et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Conformational changes in the G protein Gs induced by the β2 adrenergic receptor

(2011) Ka Young Chung et al.   NATURE

Dynamics of the Phosphoinositide 3-Kinase p110δ Interaction with p85α and Membranes Reveals Aspects of Regulation Distinct from p110α

(2011) John E. Burke et al.   STRUCTURE

Ligand-Dependent Perturbation of the Conformational Ensemble for the GPCR β2 Adrenergic Receptor Revealed by HDX

(2011) Graham M. West et al.   STRUCTURE

Allosteric Receptors: From Electric Organ to Cognition

(2010) Jean-Pierre Changeux   Annual Review of Pharmacology and Toxicology

Structure of a premicellar complex of alkyl sulfates with the interfacial binding surfaces of four subunits of phospholipase A2

(2010) Ying H. Pan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Extracellular phospholipases in atherosclerosis

(2010) Sonia-Athina Karabina et al.   BIOCHIMIE

Emerging roles for phospholipase A2 enzymes in cancer

(2010) Kieran F. Scott et al.   BIOCHIMIE

Lipoprotein-associated phospholipase A2 and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies

(2010)   LANCET

Phospholipase A2inhibitors as potential therapeutic agents for the treatment of inflammatory diseases

(2009) Victoria Magrioti et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Localizing the Membrane Binding Region of Group VIA Ca2+-independent Phospholipase A2Using Peptide Amide Hydrogen/Deuterium Exchange Mass Spectrometry

(2009) Yuan-Hao Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Location of Inhibitors Bound to Group IVA Phospholipase A2Determined by Molecular Dynamics and Deuterium Exchange Mass Spectrometry

(2009) John E. Burke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression

(2009) C. R. Kimberlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biochemistry and Physiology of Mammalian Secreted Phospholipases A2

(2008) Gérard Lambeau et al.   Annual Review of Biochemistry

Interaction of Group IA Phospholipase A2with Metal Ions and Phospholipid Vesicles Probed with Deuterium Exchange Mass Spectrometry†

(2008) John E. Burke et al.   BIOCHEMISTRY

Phospholipase A2 Biochemistry

(2008) John E. Burke et al.   CARDIOVASCULAR DRUGS AND THERAPY

A Phospholipid Substrate Molecule Residing in the Membrane Surface Mediates Opening of the Lid Region in Group IVA Cytosolic Phospholipase A2

(2008) John E. Burke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium Binding Rigidifies the C2 Domain and the Intradomain Interaction of GIVA Phospholipase A2as Revealed by Hydrogen/Deuterium Exchange Mass Spectrometry

(2008) Yuan-Hao Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Human Plasma Platelet-activating Factor Acetylhydrolase

(2008) Uttamkumar Samanta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY