Cu(II) Mediates Kinetically Distinct, Non-amyloidogenic Aggregation of Amyloid-β Peptides

Rapid Formation of a Preoligomeric Peptide-Metal-Peptide Complex Following Copper(II) Binding to Amyloid β Peptides

(2011) Jeppe T. Pedersen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two Distinct Amyloid β-Protein (Aβ) Assembly Pathways Leading to Oligomers and Fibrils Identified by Combined Fluorescence Correlation Spectroscopy, Morphology, and Toxicity Analyses

(2011) Satoko Matsumura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Effects of Zn2+, Cu2+, Fe3+, and Al3+on Amyloid-β Stability, Oligomerization, and Aggregation

(2011) Wei-Ting Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substoichiometric Levels of Cu2+Ions Accelerate the Kinetics of Fiber Formation and Promote Cell Toxicity of Amyloid-β from Alzheimer Disease

(2010) Claire J. Sarell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis

(2010) S. W. Pimplikar et al.   JOURNAL OF NEUROSCIENCE

Stabilization of neurotoxic Alzheimer amyloid-  oligomers by protein engineering

(2010) A. Sandberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pulse EPR Spectroscopy Reveals the Coordination Sphere of Copper(II) Ions in the 1–16 Amyloid-β Peptide: A Key Role of the First Two N-Terminus Residues

(2009) Pierre Dorlet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrochemical and Conformational Consequences of Copper (CuIand CuII) Binding to β-Amyloid(1-40)

(2009) Maria Brzyska  et al.   CHEMBIOCHEM

Copper and Zinc Binding to Amyloid-β: Coordination, Dynamics, Aggregation, Reactivity and Metal-Ion Transfer

(2009) Peter Faller   CHEMBIOCHEM

Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-β (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators

(2009) Vello Tõugu et al.   JOURNAL OF NEUROCHEMISTRY

Pleomorphic Copper Coordination by Alzheimer’s Disease Amyloid-β Peptide

(2009) Simon C. Drew et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Increasing Cu bioavailability inhibits A  oligomers and tau phosphorylation

(2009) P. J. Crouch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Kinetic Explorer: A new computer program for dynamic simulation and fitting of kinetic data

(2008) Kenneth A. Johnson et al.   ANALYTICAL BIOCHEMISTRY

Copper and the structural biology of the prion protein

(2008) John H. Viles et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Cu(II) Binding to Monomeric, Oligomeric, and Fibrillar Forms of the Alzheimer’s Disease Amyloid-β Peptide†

(2008) Jesse W. Karr et al.   BIOCHEMISTRY

Fitting Neurological Protein Aggregation Kinetic Data via a 2-Step, Minimal/“Ockham's Razor” Model:  The Finke−Watzky Mechanism of Nucleation Followed by Autocatalytic Surface Growth†

(2008) Aimee M. Morris et al.   BIOCHEMISTRY

Metals in Alzheimer's and Parkinson's Diseases

(2008) Kevin J Barnham et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-β peptide

(2008) Peter Faller et al.   DALTON TRANSACTIONS

Reassessing the amyloid cascade hypothesis of Alzheimer's disease

(2008) Sanjay W. Pimplikar   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Amyloid β-Protein Assembly and Alzheimer Disease

(2008) Robin Roychaudhuri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Mechanism of Thioflavin-T Binding to the Surface of β-Rich Peptide Self-Assemblies

(2008) Matthew Biancalana et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantification of the Binding Constant of Copper(II) to the Amyloid-Beta Peptide

(2008) Lanying Q. Hatcher et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Metal swap between Zn7-metallothionein-3 and amyloid-β–Cu protects against amyloid-β toxicity

(2008) Gabriele Meloni et al.   Nature Chemical Biology

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

(2003) Craig S. Atwood et al.   JOURNAL OF NEUROCHEMISTRY