l-Tryptophan-mediated Enhancement of Susceptibility to Nonalcoholic Fatty Liver Disease Is Dependent on the Mammalian Target of Rapamycin

Dietary Leucine - An Environmental Modifier of Insulin Resistance Acting on Multiple Levels of Metabolism

(2011) Yazmin Macotela et al.   PLoS One

Autophagy in health and disease. 2. Regulation of lipid metabolism and storage by autophagy: pathophysiological implications

(2010) Mark J. Czaja   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Differential effects of long-term leucine infusion on tissue protein synthesis in neonatal pigs

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Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression

(2010) Yosuke Osawa et al.   FASEB JOURNAL

The Absence of IDO Upregulates Type I IFN Production, Resulting in Suppression of Viral Replication in the Retrovirus-Infected Mouse

(2010) M. Hoshi et al.   JOURNAL OF IMMUNOLOGY

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

(2010) Jung Sub Lim et al.   Nature Reviews Gastroenterology & Hepatology

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Emerging Role of mTOR in Lipid Biosynthesis

(2009) Mathieu Laplante et al.   CURRENT BIOLOGY

Serotonin promotes tumor growth in human hepatocellular cancer

(2009) Christopher Soll et al.   HEPATOLOGY

Role of acid sphingomyelinase of Kupffer cells in cholestatic liver injury in mice

(2009) Yosuke Osawa et al.   HEPATOLOGY

Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia

(2009) Hui-Yu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapamycin Protects Against High Fat Diet–Induced Obesity in C57BL/6J Mice

(2009) Geng-Ruei Chang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Mammalian target of rapamycin (mTOR) pathway signalling in lymphomas

(2008) Elias Drakos et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Aggravation of viral hepatitis by platelet-derived serotonin

(2008) Philipp A Lang et al.   NATURE MEDICINE