Contributions of Conserved Residues at the Gating Interface of Glycine Receptors

Pathophysiological Mechanisms of Dominant and Recessive GLRA1 Mutations in Hyperekplexia

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A Cation-  Interaction at a Phenylalanine Residue in the Glycine Receptor Binding Site Is Conserved for Different Agonists

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Principles of activation and permeation in an anion-selective Cys-loop receptor

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Contributions of counter-charge in a potassium channel voltage-sensor domain

(2011) Stephan A Pless et al.   Nature Chemical Biology

Molecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels

(2011) Stephan A. Pless et al.   Nature Communications

Chemical Scale Studies of the Phe-Pro Conserved Motif in the Cys Loop of Cys Loop Receptors

(2010) Walrati Limapichat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the extracellular transmembrane domain interface in gating and pharmacology of a heteromeric neuronal nicotinic receptor

(2010) Marcos Aldea et al.   JOURNAL OF NEUROCHEMISTRY

Conformational changes in extracellular loop 2 associated with signal transduction in the glycine receptor

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Binding, activation and modulation of Cys-loop receptors

(2010) Paul S. Miller et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Ligand-specific Conformational Changes in the α1 Glycine Receptor Ligand-binding Domain

(2009) Stephan A. Pless et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Magnitude of a Conformational Change in the Glycine Receptor β1-β2 Loop Is Correlated with Agonist Efficacy

(2009) Stephan A. Pless et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotine binding to brain receptors requires a strong cation–π interaction

(2009) Xinan Xiu et al.   NATURE

Cys-Loop Neuroreceptors: Structure to the Rescue?

(2008) Dennis A. Dougherty   CHEMICAL REVIEWS

Roles for Loop 2 Residues of α1 Glycine Receptors in Agonist Activation

(2008) Daniel K. Crawford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotinic Receptor Interloop Proline Anchors β1-β2 and Cys loops in Coupling Agonist Binding to Channel Gating

(2008) Won Yong Lee et al.   JOURNAL OF GENERAL PHYSIOLOGY

A Cation-  Interaction in the Binding Site of the Glycine Receptor Is Mediated by a Phenylalanine Residue

(2008) S. A. Pless et al.   JOURNAL OF NEUROSCIENCE

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels

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