Complex Biotransformations Catalyzed by RadicalS-Adenosylmethionine Enzymes

Structural Insights into Radical Generation by the Radical SAM Superfamily

(2011) Jessica L. Vey et al.   CHEMICAL REVIEWS

Characterization of NocL Involved in Thiopeptide Nocathiacin I Biosynthesis

(2011) Qi Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Radical-mediated enzymatic carbon chain fragmentation-recombination

(2011) Qi Zhang et al.   Nature Chemical Biology

RNA methylation by Radical SAM enzymes RlmN and Cfr proceeds via methylene transfer and hydride shift

(2011) F. Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Radically Different Mechanism for S-Adenosylmethionine-Dependent Methyltransferases

(2011) T. L. Grove et al.   SCIENCE

Structural Basis for Methyl Transfer by a Radical SAM Enzyme

(2011) A. K. Boal et al.   SCIENCE

Structures of apo and GTP-bound molybdenum cofactor biosynthesis protein MoaC fromThermus thermophilusHB8

(2010) Shankar Prasad Kanaujia et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A “Radical Dance” in Thiamin Biosynthesis: Mechanistic Analysis of the Bacterial Hydroxymethylpyrimidine Phosphate Synthase

(2010) Abhishek Chatterjee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

[FeFe]-Hydrogenase Cyanide Ligands Derived From S-Adenosylmethionine-Dependent Cleavage of Tyrosine

(2010) Rebecca C. Driesener et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Adenosyl Radical: Reagent and Catalyst in Enzyme Reactions

(2010) E. Neil G. Marsh et al.   CHEMBIOCHEM

Radicals from S-adenosylmethionine and their application to biosynthesis

(2010) Peter L Roach   CURRENT OPINION IN CHEMICAL BIOLOGY

S-Adenosylmethionine-dependent radical-based modification of biological macromolecules

(2010) Mohamed Atta et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Thiazolyl Peptide Antibiotic Biosynthesis: A Cascade of Post-translational Modifications on Ribosomal Nascent Proteins

(2010) Christopher T. Walsh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

[FeFe]-Hydrogenase Maturation: HydG-Catalyzed Synthesis of Carbon Monoxide

(2010) Eric M. Shepard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RlmN and Cfr are Radical SAM Enzymes Involved in Methylation of Ribosomal RNA

(2010) Feng Yan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Moving posttranslational modifications forward to biosynthesize the glycosylated thiopeptide nocathiacin I in Nocardia sp. ATCC202099

(2010) Ying Ding et al.   Molecular BioSystems

Nosiheptide Biosynthesis Featuring a Unique Indole Side Ring Formation on the Characteristic Thiopeptide Framework

(2009) Yi Yu et al.   ACS Chemical Biology

Protein Residues That Control the Reaction Trajectory inS-Adenosylmethionine Radical Enzymes: Mutagenesis of Asparagine 153 and Aspartate 155 inEscherichia coliBiotin Synthase†

(2009) Christine E. Farrar et al.   BIOCHEMISTRY

The Deazapurine Biosynthetic Pathway Revealed: In Vitro Enzymatic Synthesis of PreQ0from Guanosine 5′-Triphosphate in Four Steps

(2009) Reid M. McCarty et al.   BIOCHEMISTRY

Thiopeptide Biosynthesis Featuring Ribosomally Synthesized Precursor Peptides and Conserved Posttranslational Modifications

(2009) Rijing Liao et al.   CHEMISTRY & BIOLOGY

Unusual Chemistry in the Biosynthesis of the Antibiotic Chondrochlorens

(2009) Shwan Rachid et al.   CHEMISTRY & BIOLOGY

Control of radical chemistry in the AdoMet radical enzymes

(2009) Kaitlin S Duschene et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Characterization and Mechanistic Studies of DesII: A RadicalS-Adenosyl-l-methionine Enzyme Involved in the Biosynthesis of TDP-d-Desosamine

(2009) Ping-Hui Szu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiostrepton Biosynthesis: Prototype for a New Family of Bacteriocins

(2009) Wendy L. Kelly et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ribosomally Synthesized Thiopeptide Antibiotics Targeting Elongation Factor Tu

(2009) Rowan P. Morris et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent advances in thiopeptideantibiotic biosynthesis

(2009) Chaoxuan Li et al.   NATURAL PRODUCT REPORTS

ThiC Is an [Fe-S] Cluster Protein That Requires AdoMet To Generate the 4-Amino-5-hydroxymethyl-2-methylpyrimidine Moiety in Thiamin Synthesis†

(2008) N. Cecilia Martinez-Gomez et al.   BIOCHEMISTRY

Reaction of AdoMet with ThiC Generates a Backbone Free Radical†

(2008) N. Cecilia Martinez-Gomez et al.   BIOCHEMISTRY

Deciphering Deazapurine Biosynthesis: Pathway for Pyrrolopyrimidine Nucleosides Toyocamycin and Sangivamycin

(2008) Reid M. McCarty et al.   CHEMISTRY & BIOLOGY

The Radical SAM Superfamily

(2008) Perry A. Frey et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily

(2008) Abhishek Chatterjee et al.   Nature Chemical Biology