Residues 155 and 348 Contribute to the Determination of P2X7Receptor Function via Distinct Mechanisms Revealed by Single-nucleotide Polymorphisms

P2X purinergic receptor ligands: recently patented compounds

(2010) Hendra Gunosewoyo et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1β secretion

(2010) Leanne Stokes et al.   FASEB JOURNAL

New structure enlivens interest in P2X receptors

(2010) Liam E. Browne et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Identification of the amino acid residues in the extracellular domain of rat P2X7receptor involved in functional inhibition by acidic pH

(2009) X Liu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors

(2009) Diana L Donnelly-Roberts et al.   BRITISH JOURNAL OF PHARMACOLOGY

Purinergic P2X7 receptors regulate secretion of interleukin-1 receptor antagonist and beta cell function and survival

(2009) R. Glas et al.   DIABETOLOGIA

P2X7-mediated chemoprevention of epithelial cancers

(2009) George I Gorodeski   EXPERT OPINION ON THERAPEUTIC TARGETS

Altered P2X7-receptor level and function in mouse models of Huntington’s disease and therapeutic efficacy of antagonist administration

(2009) Miguel Díaz-Hernández et al.   FASEB JOURNAL

The P2X7 purinergic receptor: from physiology to neurological disorders

(2009) Stephen D. Skaper et al.   FASEB JOURNAL

Activation of Microglia by Amyloid   Requires P2X7 Receptor Expression

(2009) J. M. Sanz et al.   JOURNAL OF IMMUNOLOGY

The P2X7 Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X7R Pore

(2009) M. Monif et al.   JOURNAL OF NEUROSCIENCE

Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions

(2009) Sébastien Roger et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE

Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7

(2009) Sahil Adriouch et al.   Purinergic Signalling

Identification and characterization of a novel variant of the human P2X7 receptor resulting in gain of function

(2009) Chengqun Sun et al.   Purinergic Signalling

Signaling at Purinergic P2X Receptors

(2008) Annmarie Surprenant et al.   Annual Review of Physiology

Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders

(2008) Ana M. Basso et al.   BEHAVIOURAL BRAIN RESEARCH

Homotrimeric complexes are the dominant assembly state of native P2X7 subunits

(2008) Annette Nicke   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Species and agonist dependent zinc modulation of endogenous and recombinant ATP-gated P2X7 receptors

(2008) Samantha F. Moore et al.   BIOCHEMICAL PHARMACOLOGY

MicroRNAs miR-186 and miR-150 Down-regulate Expression of the Pro-apoptotic Purinergic P2X7Receptor by Activation of Instability Sites at the 3′-Untranslated Region of the Gene That Decrease Steady-state Levels of the Transcript

(2008) Lingyin Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Purinergic P2X7Receptors Mediate ATP-induced Saliva Secretion by the Mouse Submandibular Gland

(2008) Tetsuji Nakamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Pore Residues Engaged in Determining Divalent Cationic Permeation in Transient Receptor Potential Melastatin Subtype Channel 2

(2008) Rong Xia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Facilitation of P2X7 Receptor Currents and Membrane Blebbing via Constitutive and Dynamic Calmodulin Binding

(2008) S. Roger et al.   JOURNAL OF NEUROSCIENCE

Activation of P2X7 receptors in glial satellite cells reduces pain through downregulation of P2X3 receptors in nociceptive neurons

(2008) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased P2X7Receptor Expression and Function in Thyroid Papillary Cancer: A New Potential Marker of the Disease?

(2007) Anna Solini et al.   ENDOCRINOLOGY