Biochemical, Proteomic, Structural, and Thermodynamic Characterizations of Integrin-linked Kinase (ILK)

COMP-Ang1 stimulates HIF-1 -mediated SDF-1 overexpression and recovers ischemic injury through BM-derived progenitor cell recruitment

(2011) S.-W. Youn et al.   BLOOD

BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways

(2011) Vinicio A. de Jesus Perez et al.   JOURNAL OF CELL BIOLOGY

Pseudokinases-remnants of evolution or key allosteric regulators?

(2010) Elton Zeqiraj et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Integrin-linked kinase regulates p38 MAPK-dependent cell cycle arrest in ureteric bud development

(2010) J. Smeeton et al.   DEVELOPMENT

Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer

(2010) S M Pontier et al.   ONCOGENE

Integrin-Linked Kinase Is a Functional Mn2+-Dependent Protein Kinase that Regulates Glycogen Synthase Kinase-3β (GSK-3β) Phosphorylation

(2010) Mykola Maydan et al.   PLoS One

Protein kinases: evolution of dynamic regulatory proteins

(2010) Susan S. Taylor et al.   TRENDS IN BIOCHEMICAL SCIENCES

Increased Expression of Integrin-Linked Kinase Attenuates Left Ventricular Remodeling and Improves Cardiac Function After Myocardial Infarction

(2009) Liang Ding et al.   CIRCULATION

The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!

(2009) Sara A Wickström et al.   EMBO JOURNAL

Structural Basis of Focal Adhesion Localization of LIM-only Adaptor PINCH by Integrin-linked Kinase

(2009) Yanwu Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal Adhesions

(2009) Koichi Fukuda et al.   MOLECULAR CELL

Integrin-linked kinase is an adaptor with essential functions during mouse development

(2009) Anika Lange et al.   NATURE

ROP2 from Toxoplasma gondii: A Virulence Factor with a Protein-Kinase Fold and No Enzymatic Activity

(2009) Gilles Labesse et al.   STRUCTURE

Structure of the Pseudokinase VRK3 Reveals a Degraded Catalytic Site, a Highly Conserved Kinase Fold, and a Putative Regulatory Binding Site

(2009) Eric D. Scheeff et al.   STRUCTURE

ATP and MO25α Regulate the Conformational State of the STRADα Pseudokinase and Activation of the LKB1 Tumour Suppressor

(2009) Elton Zeqiraj et al.   PLOS BIOLOGY

The Structure of α-Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly

(2008) Xiaoxia Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin-linked kinase - essential roles in physiology and cancer biology

(2008) P. C. McDonald et al.   JOURNAL OF CELL SCIENCE

The structural basis of integrin-linked kinase-PINCH interactions

(2008) B. P. Chiswell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrin β1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus

(2007) Keizo Kanasaki et al.   DEVELOPMENTAL BIOLOGY