Characterization of Sparstolonin B, a Chinese Herb-derived Compound, as a Selective Toll-like Receptor Antagonist with Potent Anti-inflammatory Properties

A new phenylpropane glycoside from the rhizome of Sparganium stoloniferum

(2010) Seung Young Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Specific Dietary Polyphenols Attenuate Atherosclerosis in Apolipoprotein E–Knockout Mice by Alleviating Inflammation and Endothelial Dysfunction

(2010) Wai Mun Loke et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis*

(2010) Todd W. Rice et al.   CRITICAL CARE MEDICINE

A new alkaloid from the stem ofSparganium stoloniferumBuch.-Ham

(2010) Shu-Xian Li et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Roles of Oral Bacteria in Cardiovascular Diseases — From Molecular Mechanisms to Clinical Cases: Implication of Periodontal Diseases in Development of Systemic Diseases

(2010) Hiroaki Inaba et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Targeting Toll-like receptors: emerging therapeutics?

(2010) Elizabeth J. Hennessy et al.   NATURE REVIEWS DRUG DISCOVERY

Inflamação sistêmica causada pela periodontite crônica em pacientes vítimas de ataque cardíaco isquêmico agudo

(2010) Fernando José de Oliveira et al.   Revista Brasileira de Cirurgia Cardiovascular

New chemical constituents from the rhizomes of Sparganium stoloniferum

(2009) Ying Xiong et al.   ARCHIVES OF PHARMACAL RESEARCH

Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins

(2009) Susan Carpenter et al.   BIOCHEMICAL JOURNAL

THE NOVEL SELECTIVE TOLL-LIKE RECEPTOR 4 SIGNAL TRANSDUCTION INHIBITOR TAK-242 PREVENTS ENDOTOXAEMIA IN CONSCIOUS GUINEA-PIGS

(2009) Masamune Kuno et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Risk of death and the efficacy of eritoran tetrasodium (E5564): Design considerations for clinical trials of anti-inflammatory agents in sepsis*

(2009) Amisha V. Barochia et al.   CRITICAL CARE MEDICINE

CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar A -Stimulated Microglial Activation

(2009) E. G. Reed-Geaghan et al.   JOURNAL OF NEUROSCIENCE

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Protection from lethal Gram-negative bacterial sepsis by targeting Toll-like receptor 4

(2009) T. Roger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TLRs and innate immunity

(2008) B. A. Beutler   BLOOD

Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

(2008) Vilma Urbonaviciute et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Emerging role of Toll-like receptors in atherosclerosis

(2008) Linda K. Curtiss et al.   JOURNAL OF LIPID RESEARCH

TLR SIGNALING PATHWAY IN PATIENTS WITH SEPSIS

(2008) Reinaldo Salomão et al.   SHOCK

Toll-Like Receptor 4 Is Involved in Subacute Stress–Induced Neuroinflammation and in the Worsening of Experimental Stroke

(2008) Javier R. Caso et al.   STROKE