Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation
Authors
Keywords
-
Journal
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 22, Issue 12, Pages 1008-1015
Publisher
Springer Nature
Online
2015-11-17
DOI
10.1038/nsmb.3127
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Genetic investigation of FOXE1 polyalanine tract in thyroid diseases: New insight on the role of FOXE1 in thyroid carcinoma
- (2017) Rihab Kallel et al. Cancer Biomarkers
- Unraveling the pathogenesis ofARXpolyalanine tract variants using a clinical and molecular interfacing approach
- (2015) Isabel Marques et al. Molecular Genetics & Genomic Medicine
- A Novel Feed-Forward Loop between ARIH2 E3-Ligase and PABPN1 Regulates Aging-Associated Muscle Degeneration
- (2014) Vered Raz et al. AMERICAN JOURNAL OF PATHOLOGY
- Misfolded Polyglutamine, Polyalanine, and Superoxide Dismutase 1 Aggregate via Distinct Pathways in the Cell
- (2014) Saskia Polling et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The unresolved puzzle why alanine extensions cause disease
- (2013) Reno Winter et al. BIOLOGICAL CHEMISTRY
- Putting Huntingtin “Aggregation” in View with Windows into the Cellular Milieu
- (2013) Danny M. Hatters CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Reduced polyalanine-expanded Arx mutant protein in developing mouse subpallium alters Lmo1 transcriptional regulation
- (2013) Kristie Lee et al. HUMAN MOLECULAR GENETICS
- A Platform to View Huntingtin Exon 1 Aggregation Flux in the Cell Reveals Divergent Influences from Chaperones hsp40 and hsp70
- (2013) Angelique R. Ormsby et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role of amyloidogenic protein oligomerization in neurodegenerative disease
- (2013) Gregor P. Lotz et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Mechanistic Insight into the Pathology of Polyalanine Expansion Disorders Revealed by a Mouse Model for X Linked Hypopituitarism
- (2013) James Hughes et al. PLoS Genetics
- Polyalanine-independent Conformational Conversion of Nuclear Poly(A)-binding Protein 1 (PABPN1)
- (2012) Reno Winter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Physical Chemistry of Polyglutamine: Intriguing Tales of a Monotonous Sequence
- (2012) Ronald Wetzel JOURNAL OF MOLECULAR BIOLOGY
- Tracking protein aggregation and mislocalization in cells with flow cytometry
- (2012) Yasmin M Ramdzan et al. NATURE METHODS
- Congenital Hydrocephalus and Abnormal Subcommissural Organ Development in Sox3 Transgenic Mice
- (2012) Kristie Lee et al. PLoS One
- Length-Dependent Aggregation of Uninterrupted Polyalanine Peptides
- (2011) Joseph P. Bernacki et al. BIOCHEMISTRY
- Assessing the contribution of heterogeneous distributions of oligomers to aggregation mechanisms of polyglutamine peptides
- (2011) Andreas Vitalis et al. BIOPHYSICAL CHEMISTRY
- The Rate of PolyQ-Mediated Aggregation Is Dramatically Affected by the Number and Location of Surrounding Domains
- (2011) Amy L. Robertson et al. JOURNAL OF MOLECULAR BIOLOGY
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- Conformation Sensors that Distinguish Monomeric Proteins from Oligomers in Live Cells
- (2010) Yasmin M. Ramdzan et al. CHEMISTRY & BIOLOGY
- ARX spectrum disorders: making inroads into the molecular pathology
- (2010) Cheryl Shoubridge et al. HUMAN MUTATION
- Tracking Mutant Huntingtin Aggregation Kinetics in Cells Reveals Three Major Populations That Include an Invariant Oligomer Pool
- (2010) Maya A. Olshina et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Non-ATG-initiated translation directed by microsatellite expansions
- (2010) T. Zu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice
- (2009) Kunio Kitamura et al. HUMAN MOLECULAR GENETICS
- Dual modes of rabies P-protein association with microtubules: a novel strategy to suppress the antiviral response
- (2009) G. W. Moseley et al. JOURNAL OF CELL SCIENCE
- Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates
- (2009) Pei-Hsien Ren et al. NATURE CELL BIOLOGY
- Molecular mechanisms underlying polyalanine diseases
- (2009) C. Messaed et al. NEUROBIOLOGY OF DISEASE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now