Weeding out bad waves: towards selective cannabinoid circuit control in epilepsy

Endocannabinoid-mediated retrograde modulation of synaptic transmission

(2014) Takako Ohno-Shosaku et al.   CURRENT OPINION IN NEUROBIOLOGY

The case for assessing cannabidiol in epilepsy

(2014) Maria Roberta Cilio et al.   EPILEPSIA

The case for medical marijuana in epilepsy

(2014) Edward Maa et al.   EPILEPSIA

Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

(2014) Orrin Devinsky et al.   EPILEPSIA

Kainate receptors in the hippocampus

(2014) Mario Carta et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Presynaptic Calcium Channel Inhibition Underlies CB1 Cannabinoid Receptor-Mediated Suppression of GABA Release

(2014) G. G. Szabo et al.   JOURNAL OF NEUROSCIENCE

Opioids induce dissociable forms of long-term depression of excitatory inputs to the dorsal striatum

(2014) Brady K Atwood et al.   NATURE NEUROSCIENCE

Gene therapy in epilepsy—is it time for clinical trials?

(2014) Dimitri M. Kullmann et al.   Nature Reviews Neurology

ABHD6 Blockade Exerts Antiepileptic Activity in PTZ-Induced Seizures and in Spontaneous Seizures in R6/2 Mice

(2014) Alipi V. Naydenov et al.   NEURON

Fast-spiking, parvalbumin+ GABAergic interneurons: From cellular design to microcircuit function

(2014) H. Hu et al.   SCIENCE

Seizing an Opportunity for the Endocannabinoid System

(2014) Bradley E. Alger   Epilepsy Currents

Quantitative assessment of CA1 local circuits: Knowledge base for interneuron-pyramidal cell connectivity

(2013) Marianne J. Bezaire et al.   HIPPOCAMPUS

CA1 Pyramidal Cell Theta-Burst Firing Triggers Endocannabinoid-Mediated Long-Term Depression at Both Somatic and Dendritic Inhibitory Synapses

(2013) T. J. Younts et al.   JOURNAL OF NEUROSCIENCE

Acute inhibition of diacylglycerol lipase blocks endocannabinoid-mediated retrograde signalling: evidence for on-demand biosynthesis of 2-arachidonoylglycerol

(2013) Yuki Hashimotodani et al.   JOURNAL OF PHYSIOLOGY-LONDON

Voltage drives diverse endocannabinoid signals to mediate striatal microcircuit-specific plasticity

(2013) Brian N Mathur et al.   NATURE NEUROSCIENCE

Mechanisms of epileptogenesis: a convergence on neural circuit dysfunction

(2013) Ethan M. Goldberg et al.   NATURE REVIEWS NEUROSCIENCE

Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling

(2013) Csaba Földy et al.   NEURON

Adolescent Cannabinoid Exposure Permanently Suppresses Cortical Oscillations in Adult Mice

(2013) Sylvina M Raver et al.   NEUROPSYCHOPHARMACOLOGY

Chronic alcohol produces neuroadaptations to prime dorsal striatal learning

(2013) Lauren DePoy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Changing the tune: plasticity and adaptation of retrograde signals

(2013) Karl J. Iremonger et al.   TRENDS IN NEUROSCIENCES

On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy

(2013) Esther Krook-Magnuson et al.   Nature Communications

The Pathophysiology of Fragile X (and What It Teaches Us about Synapses)

(2012) Asha L. Bhakar et al.   Annual Review of Neuroscience

Multiple Functions of Endocannabinoid Signaling in the Brain

(2012) István Katona et al.   Annual Review of Neuroscience

The Endocannabinoid System and the Brain

(2012) Raphael Mechoulam et al.   Annual Review of Psychology

R6/2 Huntington's Disease Mice Develop Early and Progressive Abnormal Brain Metabolism and Seizures

(2012) E. Cepeda-Prado et al.   JOURNAL OF NEUROSCIENCE

Endocannabinoid-Mediated Long-Term Depression of Afferent Excitatory Synapses in Hippocampal Pyramidal Cells and GABAergic Interneurons

(2012) Z. Peterfi et al.   JOURNAL OF NEUROSCIENCE

Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin

(2012) Anton Dvorzhak et al.   JOURNAL OF PHYSIOLOGY-LONDON

Adverse effects of antiepileptic drugs

(2012) Piero Perucca et al.   LANCET NEUROLOGY

SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance

(2012) Cristiano Nazzaro et al.   NATURE NEUROSCIENCE

Endocannabinoid Signaling and Synaptic Function

(2012) Pablo E. Castillo et al.   NEURON

Synapse type-independent degradation of the endocannabinoid 2-arachidonoylglycerol after retrograde synaptic suppression

(2012) Asami Tanimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Striatal GABAergic and cortical glutamatergic neurons mediate contrasting effects of cannabinoids on cortical network synchrony

(2012) C. Sales-Carbonell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequency-invariant temporal ordering of interneuronal discharges during hippocampal oscillations in awake mice

(2012) C. Varga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome

(2012) Kwang-Mook Jung et al.   Nature Communications

In vivo activation of endocannabinoid system in temporal lobe epilepsy with hippocampal sclerosis

(2011) K. Goffin et al.   BRAIN

Marijuana, endocannabinoids, and epilepsy: Potential and challenges for improved therapeutic intervention

(2011) Mackenzie E. Hofmann et al.   EXPERIMENTAL NEUROLOGY

Molecular and Morphological Configuration for 2-Arachidonoylglycerol-Mediated Retrograde Signaling at Mossy Cell-Granule Cell Synapses in the Dentate Gyrus

(2011) M. Uchigashima et al.   JOURNAL OF NEUROSCIENCE

Dysfunctional Prefrontal Cortical Network Activity and Interactions following Cannabinoid Receptor Activation

(2011) M. T. Kucewicz et al.   JOURNAL OF NEUROSCIENCE

Cannabinoids attenuate hippocampal gamma oscillations by suppressing excitatory synaptic input onto CA3 pyramidal neurons and fast spiking basket cells

(2011) Noémi Holderith et al.   JOURNAL OF PHYSIOLOGY-LONDON

Basket cell dichotomy in microcircuit function

(2011) Caren Armstrong et al.   JOURNAL OF PHYSIOLOGY-LONDON

Intermittent ethanol consumption depresses endocannabinoid-signaling in the dorsolateral striatum of rat

(2011) Louise Adermark et al.   NEUROPHARMACOLOGY

Exogenous and Endogenous Cannabinoids Suppress Inhibitory Neurotransmission in the Human Neocortex

(2011) Flora E Kovacs et al.   NEUROPSYCHOPHARMACOLOGY

Distribution of diacylglycerol lipase alpha, an endocannabinoid synthesizing enzyme, in the rat forebrain

(2011) J. Suárez et al.   NEUROSCIENCE

Endocannabinoids in striatal plasticity

(2011) David M. Lovinger et al.   PARKINSONISM & RELATED DISORDERS

Optogenetic Release of ACh Induces Rhythmic Bursts of Perisomatic IPSCs in Hippocampus

(2011) Daniel A. Nagode et al.   PLoS One

Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging

(2011) O. Albayram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Presynaptic LTP and LTD of Excitatory and Inhibitory Synapses

(2011) P. E. Castillo   Cold Spring Harbor Perspectives in Biology

The effect of the cannabinoid-receptor antagonist, SR141716, on the early stage of kainate-induced epileptogenesis in the adult rat

(2010) F. Edward Dudek et al.   EPILEPSIA

Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans

(2010) Zsófia Maglóczky et al.   EPILEPSIA

Presynaptic Kainate Receptor Activation Preserves Asynchronous GABA Release Despite the Reduction in Synchronous Release from Hippocampal Cholecystokinin Interneurons

(2010) M. I. Daw et al.   JOURNAL OF NEUROSCIENCE

Distinct Endocannabinoid Control of GABA Release at Perisomatic and Dendritic Synapses in the Hippocampus

(2010) S.-H. Lee et al.   JOURNAL OF NEUROSCIENCE

Enhanced Endocannabinoid Signaling Elevates Neuronal Excitability in Fragile X Syndrome

(2010) L. Zhang et al.   JOURNAL OF NEUROSCIENCE

Parvalbumin-Containing Fast-Spiking Basket Cells Generate the Field Potential Oscillations Induced by Cholinergic Receptor Activation in the Hippocampus

(2010) A. I. Gulyas et al.   JOURNAL OF NEUROSCIENCE

Loss of Retrograde Endocannabinoid Signaling and Reduced Adult Neurogenesis in Diacylglycerol Lipase Knock-out Mice

(2010) Y. Gao et al.   JOURNAL OF NEUROSCIENCE

Synaptic activation of kainate receptors gates presynaptic CB1 signaling at GABAergic synapses

(2010) Joana Lourenço et al.   NATURE NEUROSCIENCE

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system

(2010) Joel E Schlosburg et al.   NATURE NEUROSCIENCE

The Endocannabinoid 2-Arachidonoylglycerol Produced by Diacylglycerol Lipase α Mediates Retrograde Suppression of Synaptic Transmission

(2010) Asami Tanimura et al.   NEURON

Abnormal mGlu 5 Receptor/Endocannabinoid Coupling in Mice Lacking FMRP and BC1 RNA

(2010) Mauro Maccarrone et al.   NEUROPSYCHOPHARMACOLOGY

Relationship of cannabinoid CB1 receptor and cholecystokinin immunoreactivity in monkey dorsolateral prefrontal cortex

(2010) S.M. Eggan et al.   NEUROSCIENCE

Cannabinoid-Mediated Inhibition of Recurrent Excitatory Circuitry in the Dentate Gyrus in a Mouse Model of Temporal Lobe Epilepsy

(2010) Muthu D. Bhaskaran et al.   PLoS One

AAV Vector-Mediated Overexpression of CB1 Cannabinoid Receptor in Pyramidal Neurons of the Hippocampus Protects against Seizure-Induced Excitoxicity

(2010) Stephan Guggenhuber et al.   PLoS One

Endocannabinoid Signaling and Long-Term Synaptic Plasticity

(2009) Boris D. Heifets et al.   Annual Review of Physiology

Sensory gating impairments in heavy cannabis users are associated with altered neural oscillations.

(2009) Chad R. Edwards et al.   BEHAVIORAL NEUROSCIENCE

Temporal characterization of changes in hippocampal cannabinoid CB 1 receptor expression following pilocarpine-induced status epilepticus

(2009) Katherine W. Falenski et al.   BRAIN RESEARCH

The effects of intracerebroventricular AM-251, a CB1-receptor antagonist, and ACEA, a CB1-receptor agonist, on penicillin-induced epileptiform activity in rats

(2009) Ramazan Kozan et al.   EPILEPSIA

Pursuing paradoxical proconvulsant prophylaxis for epileptogenesis

(2009) Caren Armstrong et al.   EPILEPSIA

Cerebrospinal fluid levels of the endocannabinoid anandamide are reduced in patients with untreated newly diagnosed temporal lobe epilepsy

(2009) Andrea Romigi et al.   EPILEPSIA

Single application of a CB1 receptor antagonist rapidly following head injury prevents long-term hyperexcitability in a rat model

(2009) Julio Echegoyen et al.   EPILEPSY RESEARCH

Cannabinoid Modulations of Resting State EEG Theta Power and Working Memory Are Correlated in Humans

(2009) Koen B. E. Böcker et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Frequency-Dependent Inversion of Net Striatal Output by Endocannabinoid-Dependent Plasticity at Different Synaptic Inputs

(2009) L. Adermark et al.   JOURNAL OF NEUROSCIENCE

Blockade of 2-Arachidonoylglycerol Hydrolysis by Selective Monoacylglycerol Lipase Inhibitor 4-Nitrophenyl 4-(Dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances Retrograde Endocannabinoid Signaling

(2009) B. Pan et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling

(2009) Emma Puighermanal et al.   NATURE NEUROSCIENCE

Endocannabinoid-Mediated Control of Synaptic Transmission

(2009) Masanobu Kano et al.   PHYSIOLOGICAL REVIEWS

Predominant expression of phospholipase Cβ1 in telencephalic principal neurons and cerebellar interneurons, and its close association with related signaling molecules in somatodendritic neuronal elements

(2008) Masahiro Fukaya et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Downregulation of the CB1 Cannabinoid Receptor and Related Molecular Elements of the Endocannabinoid System in Epileptic Human Hippocampus

(2008) A. Ludanyi et al.   JOURNAL OF NEUROSCIENCE

Sustained increase in hippocampal sharp-wave ripple activity during slow-wave sleep after learning

(2008) O. Eschenko et al.   LEARNING & MEMORY

Endocannabinoid signaling as a synaptic circuit breaker in neurological disease

(2008) István Katona et al.   NATURE MEDICINE

Cholinergic control of GABA release: emerging parallels between neocortex and hippocampus

(2008) J. Josh Lawrence   TRENDS IN NEUROSCIENCES