The Second Messenger Cyclic Di-GMP Regulates Clostridium difficile Toxin Production by Controlling Expression of sigD

The Clostridium difficile cpr Locus Is Regulated by a Noncontiguous Two-Component System in Response to Type A and B Lantibiotics

(2013) J. M. Suarez et al.   JOURNAL OF BACTERIOLOGY

Functional Characterization of Core Components of the Bacillus subtilis Cyclic-Di-GMP Signaling Pathway

(2013) X. Gao et al.   JOURNAL OF BACTERIOLOGY

The agr Locus Regulates Virulence and Colonization Genes in Clostridium difficile 027

(2013) M. J. Martin et al.   JOURNAL OF BACTERIOLOGY

Genome-Wide Identification of Regulatory RNAs in the Human Pathogen Clostridium difficile

(2013) Olga A. Soutourina et al.   PLoS Genetics

Precise Manipulation of the Clostridium difficile Chromosome Reveals a Lack of Association between thetcdCGenotype and Toxin Production

(2012) Stephen T. Cartman et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Burden of Clostridium difficile on the Healthcare System

(2012) Erik R. Dubberke et al.   CLINICAL INFECTIOUS DISEASES

Modulation of Toxin Production by the Flagellar Regulon in Clostridium difficile

(2012) Annie Aubry et al.   INFECTION AND IMMUNITY

TheClostridium difficile spo0AGene Is a Persistence and Transmission Factor

(2012) Laura J. Deakin et al.   INFECTION AND IMMUNITY

Proline-Dependent Regulation of Clostridium difficile Stickland Metabolism

(2012) L. Bouillaut et al.   JOURNAL OF BACTERIOLOGY

Evidence for Cyclic Di-GMP-Mediated Signaling in Bacillus subtilis

(2012) Yun Chen et al.   JOURNAL OF BACTERIOLOGY

Cyclic Diguanylate Inversely Regulates Motility and Aggregation in Clostridium difficile

(2012) E. B. Purcell et al.   JOURNAL OF BACTERIOLOGY

Identification and analysis of flagellar coexpressed determinants (Feds) ofCampylobacter jejuniinvolved in colonization

(2012) Angelica M. Barrero-Tobon et al.   MOLECULAR MICROBIOLOGY

Global transcriptional control by glucose and carbon regulator CcpA in Clostridium difficile

(2012) Ana Antunes et al.   NUCLEIC ACIDS RESEARCH

TcdC Does Not Significantly Repress Toxin Expression in Clostridium difficile 630ΔErm

(2012) Dennis Bakker et al.   PLoS One

C. difficile 630Δerm Spo0A Regulates Sporulation, but Does Not Contribute to Toxin Production, by Direct High-Affinity Binding to Target DNA

(2012) Katharina E. Rosenbusch et al.   PLoS One

Pseudomonas aeruginosa Pili and Flagella Mediate Distinct Binding and Signaling Events at the Apical and Basolateral Surface of Airway Epithelium

(2012) Iwona Bucior et al.   PLoS Pathogens

The economic burden of Clostridium difficile

(2011) S.M. McGlone et al.   CLINICAL MICROBIOLOGY AND INFECTION

TcdB or not TcdB: a tale of twoClostridium difficiletoxins

(2011) Glen P Carter et al.   Future Microbiology

Mutagenic Analysis of the Clostridium difficile Flagellar Proteins, FliC and FliD, and Their Contribution to Virulence in Hamsters

(2011) Tanis C. Dingle et al.   INFECTION AND IMMUNITY

Brucella melitensis Cyclic di-GMP Phosphodiesterase BpdA Controls Expression of Flagellar Genes

(2011) E. Petersen et al.   JOURNAL OF BACTERIOLOGY

The Key Sigma Factor of Transition Phase, SigH, Controls Sporulation, Metabolism, and Virulence Factor Expression in Clostridium difficile

(2011) L. Saujet et al.   JOURNAL OF BACTERIOLOGY

Emergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage

(2011) E. Valiente et al.   JOURNAL OF MEDICAL MICROBIOLOGY

The role of toxin A and toxin B in the virulence of Clostridium difficile

(2011) Glen P. Carter et al.   TRENDS IN MICROBIOLOGY

The Anti-Sigma Factor TcdC Modulates Hypervirulence in an Epidemic BI/NAP1/027 Clinical Isolate of Clostridium difficile

(2011) Glen P. Carter et al.   PLoS Pathogens

Second Messenger-Mediated Adjustment of Bacterial Swimming Velocity

(2010) Alex Boehm et al.   CELL

CdpA Is a Burkholderia pseudomallei Cyclic di-GMP Phosphodiesterase Involved in Autoaggregation, Flagellum Synthesis, Motility, Biofilm Formation, Cell Invasion, and Cytotoxicity

(2010) H. S. Lee et al.   INFECTION AND IMMUNITY

Identification of a Genetic Locus Responsible for Antimicrobial Peptide Resistance inClostridium difficile

(2010) Shonna M. McBride et al.   INFECTION AND IMMUNITY

The emergence of ‘hypervirulence’ in Clostridium difficile

(2010) Stephen T. Cartman et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Integration of Metabolism and Virulence by Clostridium difficile CodY

(2010) S. S. Dineen et al.   JOURNAL OF BACTERIOLOGY

Human Hypervirulent Clostridium difficile Strains Exhibit Increased Sporulation as Well as Robust Toxin Production

(2010) M. Merrigan et al.   JOURNAL OF BACTERIOLOGY

Economic healthcare costs of Clostridium difficile infection: a systematic review

(2010) S.S. Ghantoji et al.   JOURNAL OF HOSPITAL INFECTION

The c-di-GMP Binding Protein YcgR Controls Flagellar Motor Direction and Speed to Affect Chemotaxis by a “Backstop Brake” Mechanism

(2010) Koushik Paul et al.   MOLECULAR CELL

CcpA-mediated repression of Clostridium difficile toxin gene expression

(2010) Ana Antunes et al.   MOLECULAR MICROBIOLOGY

Gene position in a long operon governs motility development inBacillus subtilis

(2010) Loralyn M. Cozy et al.   MOLECULAR MICROBIOLOGY

The Vibrio cholerae Flagellar Regulatory Hierarchy Controls Expression of Virulence Factors

(2009) K. A. Syed et al.   JOURNAL OF BACTERIOLOGY

Characterization of the Sporulation Initiation Pathway of Clostridium difficile and Its Role in Toxin Production

(2009) S. Underwood et al.   JOURNAL OF BACTERIOLOGY

Motility and Flagellar Glycosylation in Clostridium difficile

(2009) S. M. Twine et al.   JOURNAL OF BACTERIOLOGY

The ClosTron: Mutagenesis in Clostridium refined and streamlined

(2009) John T. Heap et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

(2009) Richard A Stabler et al.   GENOME BIOLOGY

Clostridium difficile toxin synthesis is negatively regulated by TcdC

(2008) B. Dupuy et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Identification of FleQ fromPseudomonas aeruginosaas a c-di-GMP-responsive transcription factor

(2008) Jason W. Hickman et al.   MOLECULAR MICROBIOLOGY

Mucosal penetration primes Vibrio cholerae for host colonization by repressing quorum sensing

(2008) Z. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Riboswitches in Eubacteria Sense the Second Messenger Cyclic Di-GMP

(2008) N. Sudarsan et al.   SCIENCE