Mechanisms of ribosome rescue in bacteria

Programmed –1 Frameshifting by Kinetic Partitioning during Impeded Translocation

(2014) Neva Caliskan et al.   CELL

Quantifying Absolute Protein Synthesis Rates Reveals Principles Underlying Allocation of Cellular Resources

(2014) Gene-Wei Li et al.   CELL

Resolving Nonstop Translation Complexes Is a Matter of Life or Death

(2014) K. C. Keiler et al.   JOURNAL OF BACTERIOLOGY

Translation Initiation Rate Determines the Impact of Ribosome Stalling on Bacterial Protein Synthesis

(2014) Steven J. Hersch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct tmRNA sequence elements facilitate RNase R engagement on rescued ribosomes for selective nonstop mRNA decay

(2014) Krithika Venkataraman et al.   NUCLEIC ACIDS RESEARCH

ArfA recognizes the lack of mRNA in the mRNA channel after RF2 binding for ribosome rescue

(2014) Daisuke Kurita et al.   NUCLEIC ACIDS RESEARCH

The conserved GTPase LepA contributes mainly to translation initiation in Escherichia coli

(2014) Rohan Balakrishnan et al.   NUCLEIC ACIDS RESEARCH

Translational stalling at polyproline stretches is modulated by the sequence context upstream of the stall site

(2014) Agata L. Starosta et al.   NUCLEIC ACIDS RESEARCH

Rejection of tmRNA·SmpB after GTP hydrolysis by EF-Tu on ribosomes stalled on intact mRNA

(2014) Daisuke Kurita et al.   RNA

Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome

(2014) M. G. Gagnon et al.   SCIENCE

Release of Nonstop Ribosomes Is Essential

(2014) Heather A. Feaga et al.   mBio

The Coding and Noncoding Architecture of the Caulobacter crescentus Genome

(2014) Jared M. Schrader et al.   PLoS Genetics

EF-P Dependent Pauses Integrate Proximal and Distal Signals during Translation

(2014) Sara Elgamal et al.   PLoS Genetics

Non-stop mRNA decay: a special attribute of trans-translation mediated ribosome rescue

(2014) Krithika Venkataraman et al.   Frontiers in Microbiology

Ends of the line for tmRNA-SmpB

(2014) Corey M. Hudson et al.   Frontiers in Microbiology

Trans-translation mediates tolerance to multiple antibiotics and stresses in Escherichia coli

(2013) J. Li et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

EF-G and EF4: translocation and back-translocation on the bacterial ribosome

(2013) Hiroshi Yamamoto et al.   NATURE REVIEWS MICROBIOLOGY

Identification of residues required for stalled-ribosome rescue in the codon-independent release factor YaeJ

(2013) H. Kogure et al.   NUCLEIC ACIDS RESEARCH

Molecular evolution of protein-RNA mimicry as a mechanism for translational control

(2013) A. Katz et al.   NUCLEIC ACIDS RESEARCH

tmRNA Is Essential in Shigella flexneri

(2013) Nitya S. Ramadoss et al.   PLoS One

Transimulation - Protein Biosynthesis Web Service

(2013) Marlena Siwiak et al.   PLoS One

A-Site mRNA Cleavage Is Not Required for tmRNA-Mediated ssrA-Peptide Tagging

(2013) Brian D. Janssen et al.   PLoS One

Distinct XPPX sequence motifs induce ribosome stalling, which is rescued by the translation elongation factor EF-P

(2013) L. Peil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity

(2013) N. S. Ramadoss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nascent peptides that block protein synthesis in bacteria

(2013) C. J. Woolstenhulme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Licensing and due process in the turnover of bacterial RNA

(2013) Katarzyna J. Bandyra et al.   RNA Biology

An unusual mechanism for EF-Tu activation during tmRNA-mediated ribosome rescue

(2013) M. R. Miller et al.   RNA

Mycobacterium tuberculosis possesses an unusual tmRNA rescue system

(2013) Yoann Personne et al.   TUBERCULOSIS

Divergent Protein Motifs Direct Elongation Factor P-Mediated Translational Regulation in Salmonella enterica and Escherichia coli

(2013) S. J. Hersch et al.   mBio

Proteobacterial ArfA Peptides Are Synthesized from Non-stop Messenger RNAs

(2012) Ryan E. Schaub et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ArfA Recruits RF2 into Stalled Ribosomes

(2012) Yoshihiro Shimizu   JOURNAL OF MOLECULAR BIOLOGY

ArfA recruits release factor 2 to rescue stalled ribosomes by peptidyl-tRNA hydrolysis inEscherichia coli

(2012) Yuhei Chadani et al.   MOLECULAR MICROBIOLOGY

Francisella tularensis tmRNA system mutants are vulnerable to stress, avirulent in mice, and provide effective immune protection

(2012) Anton Svetlanov et al.   MOLECULAR MICROBIOLOGY

The anti-Shine–Dalgarno sequence drives translational pausing and codon choice in bacteria

(2012) Gene-Wei Li et al.   NATURE

EF-P Is Essential for Rapid Synthesis of Proteins Containing Consecutive Proline Residues

(2012) L. K. Doerfel et al.   SCIENCE

Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches

(2012) S. Ude et al.   SCIENCE

Structural Basis for the Rescue of Stalled Ribosomes: Structure of YaeJ Bound to the Ribosome

(2012) M. G. Gagnon et al.   SCIENCE

Decoding in the Absence of a Codon by tmRNA and SmpB in the Ribosome

(2012) C. Neubauer et al.   SCIENCE

Nascent polypeptide sequences that influence ribosome function

(2011) Luis Rogelio Cruz-Vera et al.   CURRENT OPINION IN MICROBIOLOGY

trans-translation-mediated tight regulation of the expression of the alternative ribosome-rescue factor ArfA in Escherichia coli

(2011) Yuhei Chadani et al.   GENES & GENETIC SYSTEMS

Loss of Elongation Factor P Disrupts Bacterial Outer Membrane Integrity

(2011) S. B. Zou et al.   JOURNAL OF BACTERIOLOGY

tmRNA regulates synthesis of the ArfA ribosome rescue factor

(2011) Fernando Garza-Sánchez et al.   MOLECULAR MICROBIOLOGY

Escherichia coli YaeJ protein mediates a novel ribosome-rescue pathway distinct from SsrA- and ArfA-mediated pathways

(2011) Yuhei Chadani et al.   MOLECULAR MICROBIOLOGY

The tRNA synthetase paralog PoxA modifies elongation factor-P with (R)-β-lysine

(2011) Hervé Roy et al.   Nature Chemical Biology

Nascentome Analysis Uncovers Futile Protein Synthesis in Escherichia coli

(2011) Koreaki Ito et al.   PLoS One

The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis

(2011) H. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial persistence by RNA endonucleases

(2011) Etienne Maisonneuve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elongation factor P mediates a novel post-transcriptional regulatory pathway critical for bacterial virulence

(2011) S. Betty Zou et al.   Virulence

Visualizing the transfer-messenger RNA as the ribosome resumes translation

(2010) Jie Fu et al.   EMBO JOURNAL

tmRNA–SmpB: a journey to the centre of the bacterial ribosome

(2010) Félix Weis et al.   EMBO JOURNAL

The smpB-ssrA Mutant of Yersinia pestis Functions as a Live Attenuated Vaccine To Protect Mice against Pulmonary Plague Infection

(2010) N. A. Okan et al.   INFECTION AND IMMUNITY

Non-stop mRNA decay initiates at the ribosome

(2010) Zhiyun Ge et al.   MOLECULAR MICROBIOLOGY

Ribosome rescue by Escherichia coli ArfA (YhdL) in the absence of trans-translation system

(2010) Yuhei Chadani et al.   MOLECULAR MICROBIOLOGY

YaeJ is a novel ribosome-associated protein in Escherichia coli that can hydrolyze peptidyl-tRNA on stalled ribosomes

(2010) Y. Handa et al.   NUCLEIC ACIDS RESEARCH

Role of the C-terminal tail of SmpB in the early stage of trans-translation

(2010) D. Kurita et al.   RNA

Translation factor LepA contributes to tellurite resistance in Escherichia coli but plays no apparent role in the fidelity of protein synthesis

(2009) Shinichiro Shoji et al.   BIOCHIMIE

Comprehensive identification of essential Staphylococcus aureus genes using Transposon-Mediated Differential Hybridisation (TMDH)

(2009) Roy R Chaudhuri et al.   BMC GENOMICS

Beyond ribosome rescue: tmRNA and co-translational processes

(2009) Christopher S. Hayes et al.   FEBS LETTERS

RNase II is important for A-site mRNA cleavage during ribosome pausing

(2009) Fernando Garza-Sánchez et al.   MOLECULAR MICROBIOLOGY

What recent ribosome structures have revealed about the mechanism of translation

(2009) T. Martin Schmeing et al.   NATURE

Subcellular localization of a bacterial regulatory RNA

(2009) J. H. Russell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70S Ribosome

(2009) G. Blaha et al.   SCIENCE

Biology oftrans-Translation

(2008) Kenneth C. Keiler   Annual Review of Microbiology

Amino Acid Starvation and Colicin D Treatment Induce A-site mRNA Cleavage in Escherichia coli

(2008) Fernando Garza-Sánchez et al.   JOURNAL OF MOLECULAR BIOLOGY

Trans-Translation in Helicobacter pylori: Essentiality of Ribosome Rescue and Requirement of Protein Tagging for Stress Resistance and Competence

(2008) Marie Thibonnier et al.   PLoS One