Review
Biochemistry & Molecular Biology
Ivan Melnikov, Sergey Kozlov, Olga Saburova, Yuliya Avtaeva, Konstantin Guria, Zufar Gabbasov
Summary: This review aimed to trace the inflammatory pathway from the NLRP3 inflammasome to monomeric C-reactive protein (mCRP) in atherosclerotic cardiovascular disease. mCRP has a distinct proinflammatory profile and has been shown to deposit in atherosclerotic plaques and damaged tissues. Recent advances in detection techniques and the introduction of mCRP assays have made it more accessible and widely used. However, studies on compounds targeting CRP are limited to animal models or small clinical trials. Overall, the importance of this research is rated as 8 out of 10.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Mihaela-Andreea Podeanu, Adina Turcu-Stiolica, Mihaela Simona Subtirelu, Mioara Desdemona Stepan, Claudiu-Marinel Ionele, Dan-Ionut Gheonea, Bianca Stefanita Vintilescu, Raluca Elena Sandu
Summary: The study suggests that C-reactive protein (CRP) is a reliable marker for detecting inflammation in pediatric patients with metabolic syndrome (MetS). However, it may not be very accurate in distinguishing between patients with MetS and those who are obese.
Article
Immunology
Dandan Wang, Yewei Wang, Yan Chen, Lingfang Yu, Zenan Wu, Ruimei Liu, Juanjuan Ren, Xinyu Fang, Chen Zhang
Summary: This study aimed to compare the differences in cognitive functioning and inflammatory cytokine levels among different types of schizophrenia patients and healthy controls. The results showed that deficit schizophrenia patients had worse cognitive performance and higher levels of certain inflammatory cytokines compared to nondeficit schizophrenia patients and healthy controls. These findings suggest that deficit syndrome may be an independent endophenotype of schizophrenia with unique immune-inflammatory features.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Immunology
Xinpan Chen, Wang Guo, Zongli Diao, Hongdong Huang, Wenhu Liu
Summary: The lymphocyte-to-C reactive protein ratio (LCR) is a novel marker of inflammation that has been shown to predict mortality in patients with malignant cancer. This study evaluated the utility of LCR in patients undergoing hemodialysis.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Pharmacology & Pharmacy
Mustafa Karanfil, Kadriye Gayretli Yayla
Summary: The study showed that CRP, CAR, and ASI were significantly higher in hypertensive patients, while aortic strain and AoD levels were significantly lower. These findings suggest that CAR, as a novel inflammatory marker, could be a useful predictor of aortic elasticity properties in hypertensive patients.
CLINICAL AND EXPERIMENTAL HYPERTENSION
(2021)
Article
Biochemistry & Molecular Biology
Arik Sheinenzon, Mona Shehadeh, Regina Michelis, Ety Shaoul, Ohad Ronen
Summary: This study examined the correlation between albumin levels and inflammatory indices in hospitalized patients, showing negative correlations between albumin and CRP/white blood cell levels and positive correlations with platelets/hemoglobin levels. The strongest negative correlation between albumin and CRP was found in the Internal Medicine departments. Linear regression analysis revealed a minor effect of CRP on albumin levels, particularly at very high CRP levels. Further exploration of the mechanisms underlying this negative correlation is needed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Genetics & Heredity
Ross McD Young, Bruce Lawford, Rebecca Mellor, Charles P. Morris, Joanne Voisey
Summary: The study aimed to examine the relationship between CRP levels and PTSD in trauma-exposed Australian Vietnam veterans. Results showed higher serum CRP levels in PTSD patients compared to non-PTSD individuals, but this association was not significant after adjusting for BMI and triglycerides. There was no significant association found between CRP SNPs and PTSD or CRP levels.
Article
Biochemistry & Molecular Biology
Alina Frey, Daniel Martin, Louisa D'Cruz, Emmanouil Fokas, Claus Rodel, Maximilian Fleischmann
Summary: The study assessed the C-reactive protein (CRP) to albumin ratio (CAR) as a prognostic score in locally advanced non-small-cell lung cancer (NSCLC) patients treated with CRT. The findings showed that elevated CAR was associated with worse outcomes, including poorer local control and shorter survival.
Article
Clinical Neurology
Silvia Fraga, Sara Soares, Ana Cristina Santos, Henrique Barros
Summary: Children who experience physical abuse from their parents are more likely to have elevated levels of high sensitivity C-reactive protein (hs-CRP), with a positive correlation between the severity of violence and hs-CRP levels. This suggests that parental violence may have a negative impact on children's health, influencing inflammatory processes even at an early age.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Immunology
Michael Drozd, Mar Pujades-Rodriguez, Ann W. Morgan, Patrick J. Lillie, Klaus K. Witte, Mark T. Kearney, Richard M. Cubbon
Summary: Systemic inflammation assessed using C-reactive protein is common in many chronic diseases and is associated with increased long-term risk of fatal infection.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Review
Medicine, General & Internal
Crescenzo Testa, Anna Di Lorenzo, Alessandro Parlato, Giuseppe D'ambrosio, Aurora Merolla, Mario Pacileo, Gabriella Iannuzzo, Marco Gentile, Cinzia Nugara, Filippo M. Sarullo, Cesare De Gregorio, Antonello D'andrea, Carlo Vigorito, Elio Venturini, Francesco Giallauria
Summary: Atherosclerosis is a dynamic process influenced by cardiovascular risk factors, with early and late stages, where inflammation plays a key role in initiating and progressing the disease. Physical exercise has been shown to directly modulate inflammatory mediators, potentially slowing down or preventing the development of atherosclerosis.
Review
Agriculture, Dairy & Animal Science
Katarzyna Malin, Olga Witkowska-Pilaszewicz
Summary: C-reactive protein (CRP) is a major acute phase protein in dogs and is commonly used as a marker of inflammation due to its high sensitivity. It is a useful tool for guiding therapeutic decisions and can be used to monitor systemic inflammatory activity and treatment efficacy. The concentration of CRP changes rapidly with the onset and removal of inflammatory stimuli, making it a valuable indicator in clinical practice.
Article
Cell Biology
Chris P. Verschoor, Caitlyn Vlasschaert, Michael J. Rauh, Guillaume Pare
Summary: This study demonstrates that there is a strong association between circulating C-reactive protein (CRP) and age and health-related traits in older adults, and this association is more pronounced in EIS (comprehensive epigenetic inflammation score) than CRP. Additionally, experimental results show that EIS reflects the cellular response to chronic inflammation. Therefore, EIS has the potential to be a clinically relevant tool for stratifying patient risk of adverse outcomes prior to treatment or following illness.
Review
Neurosciences
Samantha F. Friend, Rahul Nachnani, Susan B. Powell, Victoria B. Risbrough
Summary: Increasing evidence suggests that inflammation, particularly C-reactive protein (CRP), plays a significant role in post-traumatic stress disorder (PTSD) and stress disorders. However, further research is needed to fully understand the mechanisms of CRP in central nervous system inflammation and its contribution to PTSD symptoms.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Review
Nutrition & Dietetics
Stefan Zivkovic, Gorica Maric, Natasa Cvetinovic, Danijela Lepojevic-Stefanovic, Bojana Bozic Cvijan
Summary: Cardiovascular diseases (CVD) are the leading cause of death worldwide. Lipid-lowering agents used in the treatment of CVD may also have anti-inflammatory and immunomodulatory properties. This review aims to evaluate the anti-inflammatory properties of currently available lipid-lowering medications, dietary supplements, and novel drugs.
Meeting Abstract
Cardiac & Cardiovascular Systems
S. Enkhjargal, S. Sonomtseren, U. Shuumarjav
Article
Biology
Kazuhiko Kotani, Uurtuya Shuumarjav, Nobuyuki Taniguchi, Toshiyuki Yamada
Article
Radiology, Nuclear Medicine & Medical Imaging
Tomoyuki Kuwata, Hironori Takahashi, Harumi Koibuchi, Kiyotake Ichizuka, Michiya Natori, Shigeki Matsubara
JOURNAL OF MEDICAL ULTRASONICS
(2016)
Article
Radiology, Nuclear Medicine & Medical Imaging
Harumi Koibuchi, Yasutomo Fujii, Yoshikazu Hirai, Takashi Mochizuki, Kohji Masuda, Kazuhiko Kotani, Toshiyuki Yamada, Nobuyuki Taniguchi
JOURNAL OF MEDICAL ULTRASONICS
(2018)
Meeting Abstract
Cardiac & Cardiovascular Systems
U. Shuumarjav, K. Kotani, N. Taniguchi
Article
Radiology, Nuclear Medicine & Medical Imaging
Shigeyoshi Kijima, Kiyoka Omoto, Kenichi Utano, Atsuko Sakamoto, Hiroaki Matsunaga, Harumi Koibuchi, Yasutomo Fujii, Nobuyuki Taniguchi, Kei Konno, Hideharu Sugimoto
JOURNAL OF MEDICAL ULTRASONICS
(2012)
Article
Radiology, Nuclear Medicine & Medical Imaging
Harumi Koibuchi, Kyoko Tsuda, Nobuyuki Taniguchi, Isamu Shimada, Tadashi Miyazawa, Takeo Sawada
JOURNAL OF MEDICAL ULTRASONICS
(2013)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Kyoko Tsuda, Kei Konno, Harumi Koibuchi, Hiroaki Matsunaga, Yasutomo Fujii, Nobuyuki Taniguchi
JOURNAL OF MEDICAL ULTRASONICS
(2012)
Article
Acoustics
Harumi Koibuchi, Kiyoka Omoto, Noriyoshi Fukushima, Tomonori Toyotsuji, Nobuyuki Taniguchi, Mikihiko Kawano
JOURNAL OF ULTRASOUND IN MEDICINE
(2014)
Review
Acoustics
Harumi Koibuchi, Kazuhiko Kotani, Nobuyuki Taniguchi
MEDICAL ULTRASONOGRAPHY
(2013)
Article
Radiology, Nuclear Medicine & Medical Imaging
Harumi Koibuchi, Yasutomo Fujii, Yusuke Sato'o, Takashi Mochizuki, Toshiyuki Yamada, Longzhu Cui, Nobuyuki Taniguchi
Summary: The study investigated the inhibition of Staphylococcus epidermidis biofilm formation by low-intensity ultrasound irradiation. Continuous wave ultrasound for 24 hours significantly inhibited biofilm formation, while double pulsed wave ultrasound for 20 minutes showed better effectiveness in inhibiting biofilm formation.
JOURNAL OF MEDICAL ULTRASONICS
(2021)
Correction
Radiology, Nuclear Medicine & Medical Imaging
Harumi Koibuchi, Yasutomo Fujii, Yusuke Sato'o, Takashi Mochizuki, Toshiyuki Yamada, Longzhu Cui, Nobuyuki Taniguchi
JOURNAL OF MEDICAL ULTRASONICS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Harumi Koibuchi, Mai Ishikawa, Sayaka Yamamoto, Kei Konno, Hirofumi Okada, Yusuke Amano, Toshiyuki Yamada, Nobuyuki Taniguchi
Summary: This report presents a case of metastasis and lymphovascular invasion of malignant melanoma in a patient who underwent tumor resection.
JOURNAL OF ULTRASOUND
(2023)
Review
Pediatrics
Harumi Koibuchi, Kazuhiko Kotani, Takaomi Minami, Kei Konno, Nobuyuki Taniguchi
MINERVA PEDIATRICA
(2016)
Article
Public, Environmental & Occupational Health
Kazuhiko Kotani, Toshiyuki Yamada, Shuumarjav Uurtuya, Nobuyuki Taniguchi
ETHNICITY & DISEASE
(2012)
