Reprogramming fibroblasts toward cardiomyocytes, neural stem cells and hepatocytes by cell activation and signaling-directed lineage conversion

Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming

(2014) Yuanyuan Du et al.   Cell Stem Cell

Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes

(2014) Pengyu Huang et al.   Cell Stem Cell

Small Molecules Facilitate the Reprogramming of Mouse Fibroblasts into Pancreatic Lineages

(2014) Ke Li et al.   Cell Stem Cell

Mouse liver repopulation with hepatocytes generated from human fibroblasts

(2014) Saiyong Zhu et al.   NATURE

Translational strategies and challenges in regenerative medicine

(2014) Stefanie Dimmeler et al.   NATURE MEDICINE

Cell and tissue engineering for liver disease

(2014) S. N. Bhatia et al.   Science Translational Medicine

Small Molecules Enable Cardiac Reprogramming of Mouse Fibroblasts with a Single Factor, Oct4

(2014) Haixia Wang et al.   Cell Reports

Conversion of Human Fibroblasts to Functional Endothelial Cells by Defined Factors

(2013) Jun Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells

(2013) Saiyong Zhu et al.   CELL RESEARCH

Generation of Integration-free and Region-Specific Neural Progenitors from Primate Fibroblasts

(2013) Jianfeng Lu et al.   Cell Reports

Cellular reprogramming: a small molecule perspective

(2012) Baoming Nie et al.   CURRENT OPINION IN CELL BIOLOGY

Heart repair by reprogramming non-myocytes with cardiac transcription factors

(2012) Kunhua Song et al.   NATURE

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

(2012) Li Qian et al.   NATURE

Conversion of human fibroblasts to angioblast-like progenitor cells

(2012) Leo Kurian et al.   NATURE METHODS

Generation of integration-free neural progenitor cells from cells in human urine

(2012) Lihui Wang et al.   NATURE METHODS

Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels

(2012) A. Margariti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical Strategies for Stem Cell Biology and Regenerative Medicine

(2011) Saiyong Zhu et al.   Annual Review of Biomedical Engineering

Recent advances in chemically induced reprogramming

(2011) Saiyong Zhu et al.   CELL CYCLE

Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

(2011) Pengyu Huang et al.   NATURE

Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors

(2011) Sayaka Sekiya et al.   NATURE

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

(2011) Jem A. Efe et al.   NATURE CELL BIOLOGY

A more efficient method to generate integration-free human iPS cells

(2011) Keisuke Okita et al.   NATURE METHODS

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

(2011) W. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct reprogramming of mouse fibroblasts to neural progenitors

(2011) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brief Report: Combined Chemical Treatment Enables Oct4-Induced Reprogramming from Mouse Embryonic Fibroblasts

(2011) Xu Yuan et al.   STEM CELLS

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

(2010) Masaki Ieda et al.   CELL

Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds

(2010) Saiyong Zhu et al.   Cell Stem Cell

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

(2010) Luigi Warren et al.   Cell Stem Cell

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells

(2009) Zhihua Song et al.   CELL RESEARCH

Expression of stem cell pluripotency factors during regeneration in newts

(2009) Nobuyasu Maki et al.   DEVELOPMENTAL DYNAMICS

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

(2009) Karim Si-Tayeb et al.   HEPATOLOGY

Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development

(2008) Charles E. Murry et al.   CELL

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE