Genome-wide mapping of embedded ribonucleotides and other noncanonical nucleotides using emRiboSeq and EndoSeq

Redundancy in ribonucleotide excision repair: Competition, compensation, and cooperation

(2015) Alexandra Vaisman et al.   DNA REPAIR

Lagging-strand replication shapes the mutational landscape of the genome

(2015) Martin A. M. Reijns et al.   NATURE

Ribose-seq: global mapping of ribonucleotides embedded in genomic DNA

(2015) Kyung Duk Koh et al.   NATURE METHODS

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

(2015) Anders R Clausen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A global profile of replicative polymerase usage

(2015) Yasukazu Daigaku et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evidence that processing of ribonucleotides in DNA by topoisomerase 1 is leading-strand specific

(2015) Jessica S Williams et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribonucleotides in DNA: hidden in plain sight

(2015) Sue Jinks-Robertson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular underpinnings of Aprataxin RNA/DNA deadenylase function and dysfunction in neurological disease

(2015) Matthew J. Schellenberg et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

(2015) Anders R Clausen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A global profile of replicative polymerase usage

(2015) Yasukazu Daigaku et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evidence that processing of ribonucleotides in DNA by topoisomerase 1 is leading-strand specific

(2015) Jessica S Williams et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribonucleotides in DNA: hidden in plain sight

(2015) Sue Jinks-Robertson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribonucleotide triggered DNA damage and RNA-DNA damage responses

(2015) Bret D Wallace et al.   RNA Biology

Ribonuclease H2 in health and disease

(2014) Martin A.M. Reijns et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Ribonucleotides in DNA: Origins, repair and consequences

(2014) Jessica S. Williams et al.   DNA REPAIR

High resolution mapping of modified DNA nucleobases using excision repair enzymes

(2014) D. Suzi Bryan et al.   GENOME RESEARCH

Reduction of hRNase H2 activity in Aicardi–Goutières syndrome cells leads to replication stress and genome instability

(2014) Sara Pizzi et al.   HUMAN MOLECULAR GENETICS

Defective removal of ribonucleotides from DNA promotes systemic autoimmunity

(2014) Claudia Günther et al.   JOURNAL OF CLINICAL INVESTIGATION

A Saccharomyces cerevisiae RNase H2 Interaction Network Functions To Suppress Genome Instability

(2014) S. Allen-Soltero et al.   MOLECULAR AND CELLULAR BIOLOGY

Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms

(2014) Catherine J. Potenski et al.   NATURE

How the misincorporation of ribonucleotides into genomic DNA can be both harmful and helpful to cells

(2014) Catherine J. Potenski et al.   NUCLEIC ACIDS RESEARCH

Arabidopsis thaliana RNase H2 Deficiency Counteracts the Needs for the WEE1 Checkpoint Kinase but Triggers Genome Instability

(2014) P. Kalhorzadeh et al.   PLANT CELL

Ribose--An Internal Threat to DNA

(2014) K. W. Caldecott   SCIENCE

Two distinct mechanisms of Topoisomerase 1-dependent mutagenesis in yeast

(2013) Jang-Eun Cho et al.   DNA REPAIR

Topoisomerase 1-Mediated Removal of Ribonucleotides from Nascent Leading-Strand DNA

(2013) Jessica S. Williams et al.   MOLECULAR CELL

Ribonucleotides Misincorporated into DNA Act as Strand-Discrimination Signals in Eukaryotic Mismatch Repair

(2013) Medini Manohar Ghodgaonkar et al.   MOLECULAR CELL

Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors

(2013) Scott A. Lujan et al.   MOLECULAR CELL

Aprataxin resolves adenylated RNA–DNA junctions to maintain genome integrity

(2013) Percy Tumbale et al.   NATURE

Cost of rNTP/dNTP pool imbalance at the replication fork

(2013) N. Y. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Removal of Misincorporated Ribonucleotides from Prokaryotic Genomes: An Unexpected Role for Nucleotide Excision Repair

(2013) Alexandra Vaisman et al.   PLoS Genetics

Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development

(2012) Martin A.M. Reijns et al.   CELL

Ribonucleotide incorporation, proofreading and bypass by human DNA polymerase δ

(2012) Anders R. Clausen et al.   DNA REPAIR

Human DNA Polymerase ϵ Is Able to Efficiently Extend from Multiple Consecutive Ribonucleotides

(2012) A. Yasemin Göksenin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity

(2012) Bjoern Hiller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

RNase H2-Initiated Ribonucleotide Excision Repair

(2012) Justin L. Sparks et al.   MOLECULAR CELL

RNase H and Postreplication Repair Protect Cells from Ribonucleotides Incorporated in DNA

(2012) Federico Lazzaro et al.   MOLECULAR CELL

Ribonucleotides and manganese ions improve non-homologous end joining by human Polµ

(2012) Maria Jose Martin et al.   NUCLEIC ACIDS RESEARCH

The catalytic cycle for ribonucleotide incorporation by human DNA Pol λ

(2012) Rajendrakumar A. Gosavi et al.   NUCLEIC ACIDS RESEARCH

Causes and consequences of ribonucleotide incorporation into nuclear DNA

(2012) Jacob Z. Dalgaard   TRENDS IN GENETICS

Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ɛ

(2011) Alan B. Clark et al.   DNA REPAIR

Ribonucleotide Discrimination and Reverse Transcription by the Human Mitochondrial DNA Polymerase

(2011) Rajesh Kasiviswanathan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutagenic Processing of Ribonucleotides in DNA by Yeast Topoisomerase I

(2011) N. Kim et al.   SCIENCE

The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease

(2010) Martin A. M. Reijns et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome instability due to ribonucleotide incorporation into DNA

(2010) Stephanie A Nick McElhinny et al.   Nature Chemical Biology

Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases

(2010) S. A. Nick McElhinny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA