Long-term maintenance of HepaRG cells in serum-free conditions and application in a repeated dose study

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(2013) Yoram Vodovotz et al.   MOLECULAR MEDICINE

In vitro biokinetics of chlorpromazine and the influence of different dose metrics on effect concentrations for cytotoxicity in Balb/c 3T3, Caco-2 and HepaRG cell cultures

(2013) Jessica J.W. Broeders et al.   TOXICOLOGY IN VITRO

Stable isotope-assisted metabolomics to detect metabolic flux changes in mammalian cell cultures

(2012) Daniel Mueller et al.   CURRENT OPINION IN BIOTECHNOLOGY

VEGF165 expressing bone marrow mesenchymal stem cells differentiate into hepatocytes under HGF and EGF induction in vitro

(2012) Yan Tan et al.   CYTOTECHNOLOGY

Biotransformation of diclofenac and effects on the metabolome of primary human hepatocytes upon repeated dose exposure

(2012) Daniel Mueller et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Three-Dimensional HepaRG Model As An Attractive Tool for Toxicity Testing

(2012) Sofia B. Leite et al.   TOXICOLOGICAL SCIENCES

Optimization of the HepaRG cell model for drug metabolism and toxicity studies

(2012) Sébastien Anthérieu et al.   TOXICOLOGY IN VITRO

Freezing solution containing dimethylsulfoxide and fetal calf serum maintains survival and ultrastructure of goat preantral follicles after cryopreservation and in vitro culture of ovarian tissue

(2011) Simone Vieira Castro et al.   CELL AND TISSUE RESEARCH

Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in heparg cells

(2011) Sébastien Anthérieu et al.   HEPATOLOGY

Effects of DMSO on gene expression in human and rat hepatocytes

(2011) Kayo Sumida et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

The HepaRG cell line is suitable for bioartificial liver application

(2011) Ruurdtje Hoekstra et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Development of a serum-free human cornea construct for in vitro drug absorption studies: The influence of varying cultivation parameters on barrier characteristics

(2011) Matthias Hahne et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

An adaptation of the human HepaRG cells to the in vitro micronucleus assay

(2011) R. Josse et al.   MUTAGENESIS

Automated detection of hepatotoxic compounds in human hepatocytes using HepaRG cells and image-based analysis of mitochondrial dysfunction with JC-1 dye

(2011) K. Pernelle et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes

(2011) Alice Limonciel et al.   TOXICOLOGY IN VITRO

Heparin-based hydrogel as a matrix for encapsulation and cultivation of primary hepatocytes

(2010) Mihye Kim et al.   BIOMATERIALS

Medium optimization based on the metabolic-flux spectrum of recombinantEscherichia colifor high expression of human-like collagen II

(2010) Jiaqing Guo et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro

(2010) Marc Lübberstedt et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line Hep G2

(2009) Jens Niklas et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: A review

(2008) M. F. B. Silva et al.   JOURNAL OF INHERITED METABOLIC DISEASE