(+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo

α-Tocopheryl succinate induces apoptosis in erbB2-expressing breast cancer cell via NF-κB pathway

(2010) Xiu-fang Wang et al.   ACTA PHARMACOLOGICA SINICA

PML/RARA Oxidation and Arsenic Binding Initiate the Antileukemia Response of As2O3

(2010) Marion Jeanne et al.   CANCER CELL

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

Mitochondrial calcium and the permeability transition in cell death

(2009) John J. Lemasters et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia

(2009) F. C. Guibal et al.   BLOOD

Mitochondrial Uncoupling and the Warburg Effect: Molecular Basis for the Reprogramming of Cancer Cell Metabolism

(2009) I. Samudio et al.   CANCER RESEARCH

Suppression of Tumor Growth In vivo by the Mitocan  -tocopheryl Succinate Requires Respiratory Complex II

(2009) L.-F. Dong et al.   CLINICAL CANCER RESEARCH

Acute promyelocytic leukemia in very elderly patients: still a clinical challenge

(2009) Fabio Forghieri et al.   LEUKEMIA & LYMPHOMA

Treatment of elderly adults with acute promyelocytic leukemia: put the pedal to metal

(2009) Martin S. Tallman   LEUKEMIA & LYMPHOMA

The production of reactive oxygen species by complex I

(2008) Judy Hirst et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mammalian complex I: A regulable and vulnerable pacemaker in mitochondrial respiratory function

(2008) Sergio Papa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet

(2008) M. A. Sanz et al.   BLOOD

Acute promyelocytic leukemia: from highly fatal to highly curable

(2008) Z.-Y. Wang et al.   BLOOD

Granzyme A Cleaves a Mitochondrial Complex I Protein to Initiate Caspase-Independent Cell Death

(2008) Denis Martinvalet et al.   CELL

Mitochondrial membrane cholesterol, the voltage dependent anion channel (VDAC), and the Warburg effect

(2008) Andrew M. Campbell et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Effective Treatment of Acute Promyelocytic Leukemia With All-Trans-Retinoic Acid, Arsenic Trioxide, and Gemtuzumab Ozogamicin

(2008) Farhad Ravandi et al.   JOURNAL OF CLINICAL ONCOLOGY

Apoptosis induction by (+)α-tocopheryl succinate in the absence or presence of all-trans retinoic acid and arsenic trioxide in NB4, NB4-R2 and primary APL cells

(2008) Rosana Aparecida Freitas et al.   LEUKEMIA RESEARCH

Apoptosis-associated mitochondrial outer membrane permeabilization assays

(2008) Damien Arnoult   METHODS

α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II

(2008) L-F Dong et al.   ONCOGENE