Self-reactive IgE exacerbates interferon responses associated with autoimmunity

Molecular basis for antagonistic activity of anifrolumab, an anti-interferon–α receptor 1 antibody

(2015) Li Peng et al.   mAbs

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

(2014) Sarah L. Rowland et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunoglobulin E plays an immunoregulatory role in lupus

(2014) Barbara Dema et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD19 and CD32b Differentially Regulate Human B Cell Responsiveness

(2014) J. L. Karnell et al.   JOURNAL OF IMMUNOLOGY

A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthma

(2014) E Suzanne Cohen et al.   mAbs

Autoreactive IgE Is Prevalent in Systemic Lupus Erythematosus and Is Associated with Increased Disease Activity and Nephritis

(2014) Barbara Dema et al.   PLoS One

Helminth Allergens, Parasite-Specific IgE, and Its Protective Role in Human Immunity

(2014) Colin Matthew Fitzsimmons et al.   Frontiers in Immunology

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Long Term Persistence of IgE Anti-Influenza Virus Antibodies in Pediatric and Adult Serum Post Vaccination with Influenza Virus Vaccine

(2012) Tamar A. Smith-Norowitz et al.   International Journal of Medical Sciences

Innate immune responses to rhinovirus are reduced by the high-affinity IgE receptor in allergic asthmatic children

(2012) Sandy R. Durrani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

An Image Analysis Method for the Precise Selection and Quantitation of Fluorescently Labeled Cellular Constituents

(2012) Chibeza C. Agley et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Differences in Autoantibody Profiles and Disease Activity and Damage Scores Between Childhood- and Adult-Onset Systemic Lupus Erythematosus: A Meta-Analysis

(2012) Brieanna Livingston et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Unmet medical needs in systemic lupus erythematosus

(2012) Aisha Lateef et al.   ARTHRITIS RESEARCH & THERAPY

Transmembrane Mutations in Toll-like Receptor 9 Bypass the Requirement for Ectodomain Proteolysis and Induce Fatal Inflammation

(2011) Maria L. Mouchess et al.   IMMUNITY

CCR7 Essentially Contributes to the Homing of Plasmacytoid Dendritic Cells to Lymph Nodes under Steady-State As Well As Inflammatory Conditions

(2011) S. Seth et al.   JOURNAL OF IMMUNOLOGY

Whole-Molecule Antibody Engineering: Generation of a High-Affinity Anti-IL-6 Antibody with Extended Pharmacokinetics

(2011) Donna K. Finch et al.   JOURNAL OF MOLECULAR BIOLOGY

Discrepancies in glomerular and tubulointerstitial/vascular immune complex IgG subclasses in lupus nephritis

(2011) AA Satoskar et al.   LUPUS

Autoimmune Response of IgE Antibodies to Cellular Self-Antigens in Systemic Lupus Erythematosus

(2010) Ajax Mercês Atta et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Counterregulation between the Fc RI Pathway and Antiviral Responses in Human Plasmacytoid Dendritic Cells

(2010) M. A. Gill et al.   JOURNAL OF IMMUNOLOGY

Basophils and the T helper 2 environment can promote the development of lupus nephritis

(2010) Nicolas Charles et al.   NATURE MEDICINE

Bifurcation of Toll-Like Receptor 9 Signaling by Adaptor Protein 3

(2010) M. Sasai et al.   SCIENCE

Structural characterization of a human Fc fragment engineered for lack of effector functions

(2008) Vaheh Oganesyan et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Specificity and affinity of human Fc  receptors and their polymorphic variants for human IgG subclasses

(2008) P. Bruhns et al.   BLOOD

The development of allergic inflammation

(2008) Stephen J. Galli et al.   NATURE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY