A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthma

Effects of Omalizumab in Non-Atopic Asthma: Results from a Spanish Multicenter Registry

(2013) Luis Pérez de Llano et al.   JOURNAL OF ASTHMA

The eXpeRience registry: The ‘real-world’ effectiveness of omalizumab in allergic asthma

(2013) G.-J. Braunstahl et al.   RESPIRATORY MEDICINE

Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor Fc RI

(2012) B. Dhaliwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beneficial Effects of Treatment With Anti-IgE Antibodies (Omalizumab) in a Patient With Severe Asthma and Negative Skin-Prick Test Results

(2011) Maarten van den Berge et al.   CHEST

CD23-Dependent Transcytosis of IgE and Immune Complex across the Polarized Human Respiratory Epithelial Cells

(2011) S. Palaniyandi et al.   JOURNAL OF IMMUNOLOGY

Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcɛRI

(2011) Mary D Holdom et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

IgE antibody-specific activity in human allergic disease

(2010) Robert G. Hamilton et al.   IMMUNOLOGIC RESEARCH

The size of the disease relevant IgE antibody fraction in relation to ‘total-IgE’ predicts the efficacy of anti-IgE (Xolair®) treatment

(2009) S. G. O. Johansson et al.   ALLERGY

Relationship between pretreatment specific IgE and the response to omalizumab therapy

(2009) U. Wahn et al.   ALLERGY

A therapeutic antibody and its antigen form different complexes in serum than in phosphate-buffered saline: A study by analytical ultracentrifugation

(2009) Barthélemy Demeule et al.   ANALYTICAL BIOCHEMISTRY

Relationship between omalizumab pharmacokinetics, IgE pharmacodynamics and symptoms in patients with severe persistent allergic (IgE-mediated) asthma

(2009) Philip J. Lowe et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Xolair Is Effective in Allergics with a Low Serum IgE Level

(2009) J. Ankerst et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Use of Quantitative Pharmacology in the Development of HAE1, a High-Affinity Anti-IgE Monoclonal Antibody

(2008) Wendy S. Putnam et al.   AAPS Journal

Allergen skin tests and free IgE levels during reduction and cessation of omalizumab therapy

(2008) Jonathan Corren et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Modelling the human immune response: performance of a 1011 human antibody repertoire against a broad panel of therapeutically relevant antigens

(2008) C. Lloyd et al.   PROTEIN ENGINEERING DESIGN & SELECTION