The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth

Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance

(2014) M. Buscarlet et al.   BLOOD

Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia

(2014) Ila Joshi et al.   NATURE IMMUNOLOGY

Stage-specific control of early B cell development by the transcription factor Ikaros

(2014) Tanja A Schwickert et al.   NATURE IMMUNOLOGY

Chromatin state dynamics during blood formation

(2014) D. Lara-Astiaso et al.   SCIENCE

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

(2013) J. Shi et al.   GENES & DEVELOPMENT

Flexible Long-Range Loops in the VH Gene Region of the Igh Locus Facilitate the Generation of a Diverse Antibody Repertoire

(2013) Jasna Medvedovic et al.   IMMUNITY

Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals

(2013) Beate Heizmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Modification of Enhancer Chromatin: What, How, and Why?

(2013) Eliezer Calo et al.   MOLECULAR CELL

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations

(2012) Yu Zhang et al.   CELL

The SWI/SNF-like BAF Complex Is Essential for Early B Cell Development

(2012) J. Choi et al.   JOURNAL OF IMMUNOLOGY

E2A and CBP/p300 Act in Synergy To Promote Chromatin Accessibility of the Immunoglobulin   Locus

(2012) S. Sakamoto et al.   JOURNAL OF IMMUNOLOGY

Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate

(2012) Yin C Lin et al.   NATURE IMMUNOLOGY

Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate

(2012) R. Mansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Distal VH Gene Cluster of the Igh Locus Contains Distinct Regulatory Elements with Pax5 Transcription Factor-Dependent Activity in Pro-B Cells

(2011) Anja Ebert et al.   IMMUNITY

B Lymphocyte Commitment Program Is Driven by the Proto-Oncogene c-myc

(2011) M. Vallespinos et al.   JOURNAL OF IMMUNOLOGY

Fate Mapping Reveals Separate Origins of T Cells and Myeloid Lineages in the Thymus

(2010) Susan M. Schlenner et al.   IMMUNITY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Chromatin remodelling during development

(2010) Lena Ho et al.   NATURE

Mediator and cohesin connect gene expression and chromatin architecture

(2010) Michael H. Kagey et al.   NATURE

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

(2010) Yin C Lin et al.   NATURE IMMUNOLOGY

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

(2009) M. A. Inlay et al.   GENES & DEVELOPMENT

Cutting Edge: SWI/SNF Mediates Antisense Igh Transcription and Locus-Wide Accessibility in B Cell Precursors

(2009) O. A. Osipovich et al.   JOURNAL OF IMMUNOLOGY

Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5

(2009) H. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells

(2008) R. Mansson et al.   BLOOD

The 3D Structure of the Immunoglobulin Heavy-Chain Locus: Implications for Long-Range Genomic Interactions

(2008) Suchit Jhunjhunwala et al.   CELL