☆ 4.7 Editorial Material

ILC development: TCF-1 reporting in

NATURE IMMUNOLOGY (2015)

Journal

NATURE IMMUNOLOGY

Volume 16, Issue 10, Pages 1011-1012

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NATURE PUBLISHING GROUP

DOI: 10.1038/ni.3276

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Immunology

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Abstract

The transcriptional regulator TCF-1 marks rare progenitor cells in adult bone marrow that have lost the potential to develop into the lymphocyte lineage but can give rise to all innate lymphoid cell lineages.

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Morris, Christopher E. Shaw, Amanda J. Myers, Jens Wiltfang, Sid O'Bryant, John M. Olichney, Victoria Alvarez, Joseph E. Parisi, Andrew B. Singleton, Henry L. Paulson, John Collinge, William R. Perry, Simon Mead, Elaine Peskind, David H. Cribbs, Martin Rossor, Aimee Pierce, Natalie S. Ryan, Wayne W. Poon, Benedetta Nacmias, Huntington Potter, Sandro Sorbi, Joseph F. Quinn, Eleonora Sacchinelli, Ashok Raj, Gianfranco Spalletta, Murray Raskind, Carlo Caltagirone, Paola Bossu, Maria Donata Orfei, Barry Reisberg, Robert Clarke, Christiane Reitz, A. David Smith, John M. Ringman, Donald Warden, Erik D. Roberson, Gordon Wilcock, Ekaterina Rogaeva, Amalia Cecilia Bruni, Howard J. Rosen, Maura Gallo, Roger N. Rosenberg, Yoav Ben-Shlomo, Mark A. Sager, Patrizia Mecocci, Andrew J. Saykin, Pau Pastor, Michael L. Cuccaro, Jeffery M. Vance, Julie A. Schneider, Lori S. Schneider, Susan Slifer, William W. Seeley, Amanda G. Smith, Joshua A. Sonnen, Salvatore Spina, Robert A. Stern, Russell H. Swerdlow, Mitchell Tang, Rudolph E. Tanzi, John Q. Trojanowski, Juan C. Troncoso, Vivianna M. Van Deerlin, Linda J. Van Eldik, Harry V. Vinters, Jean Paul Vonsattel, Sandra Weintraub, Kathleen A. Welsh-Bohmer, Kirk C. Wilhelmsen, Jennifer Williamson, Thomas S. Wingo, Randall L. Woltjer, Clinton B. Wright, Chang-En Yu, Lei Yu, Yasaman Saba, Alberto Pilotto, Maria J. Bullido, Oliver Peters, Paul K. Crane, David Bennett, Paola Bosco, Eliecer Coto, Virginia Boccardi, Phil L. De Jager, Alberto Lleo, Nick Warner, Oscar L. Lopez, Martin Ingelsson, Panagiotis Deloukas, Carlos Cruchaga, Caroline Graff, Rhian Gwilliam, Myriam Fornage, Alison M. Goate, Pascual Sanchez-Juan, Patrick G. Kehoe, Najaf Amin, Nilifur Ertekin-Taner, Claudine Berr, Stphanie Debette, Seth Love, Lenore J. Launer, Steven G. Younkin, Jean-Francois Dartigues, Chris Corcoran, M. Arfan Ikram, Dennis W. Dickson, Gael Nicolas, Dominique Campion, JoAnn Tschanz, Helena Schmidt, Hakon Hakonarson, Jordi Clarimon, Ron Munger, Reinhold Schmidt, Lindsay A. Farrer, Christine Van Broeckhoven, Michael C. O'Donovan, Anita L. DeStefano, Lesley Jones, Jonathan L. Haines, Jean-Francois Deleuze, Michael J. Owen, Vilmundur Gudnason, Richard Mayeux, Valentina Escott-Price, Bruce M. Psaty, Alfredo Ramirez, Li-San Wang, Agustin Ruiz, Cornelia M. van Duijn, Peter A. Holmans, Sudha Seshadri, Julie Williams, Phillippe Amouyel, Gerard D. Schellenberg, Jean-Charles Lambert, Margaret A. Pericak-Vance

NATURE GENETICS (2019)

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Article Multidisciplinary Sciences

TOX is a critical regulator of tumour-specific T cell differentiation

Andrew C. Scott, Friederike Dundar, Paul Zumbo, Smita S. Chandran, Christopher A. Klebanoff, Mojdeh Shakiba, Prerak Trivedi, Laura Menocal, Heather Appleby, Steven Camara, Dmitriy Zamarin, Tyler Walther, Alexandra Snyder, Matthew R. Femia, Elizabeth A. Comen, Hannah Y. Wen, Matthew D. Hellmann, Niroshana Anandasabapathy, Yong Liu, Nasser K. Altorki, Peter Lauer, Olivier Levy, Michael S. Glickman, Jonathan Kaye, Doron Betel, Mary Philip, Andrea Schietinger

NATURE (2019)

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Article Multidisciplinary Sciences

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

Omar Khan, Josephine R. Giles, Sierra McDonald, Sasikanth Manne, Shin Foong Ngiow, Kunal P. Patel, Michael T. Werner, Alexander C. Huang, Katherine A. Alexander, Jennifer E. Wu, John Attanasio, Patrick Yan, Sangeeth M. George, Bertram Bengsch, Ryan P. Staupe, Greg Donahue, Wei Xu, Ravi K. Amaravadi, Xiaowei Xu, Giorgos C. Karakousis, Tara C. Mitchell, Lynn M. Schuchter, Jonathan Kaye, Shelley L. Berger, E. John Wherry

NATURE (2019)

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Article Biology

Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy

Megan M. Tu, Hany A. Abdel-Hafiz, Robert T. Jones, Annie Jean, Katelyn J. Hoff, Jason E. Duex, Ana Chauca-Diaz, James C. Costello, Garrett M. Dancik, Beth A. Jiron Tamburini, Bogdan Czerniak, Jonathan Kaye, Dan Theodorescu

COMMUNICATIONS BIOLOGY (2020)

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Article Multidisciplinary Sciences

Persistence of self-reactive CD8+T cells in the CNS requires TOX-dependent chromatin remodeling

Nicolas Page, Sylvain Lemeille, Ilena Vincenti, Bogna Klimek, Alexandre Mariotte, Ingrid Wagner, Giovanni Di Liberto, Jonathan Kaye, Doron Merkler

Summary: The study characterizes the transcriptional and epigenetic landscape of self-reactive CD8+ T cells in central nervous system autoimmunity, showing that the TOX gene is crucial for the maintenance of self-reactive CD8+ T cells. Continuous exposure to CNS self-antigen sustains TOX levels in self-reactive CD8+ T cells.

NATURE COMMUNICATIONS (2021)

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Meeting Abstract Immunology

Development of group-3 innate lymphoid cells via Tox2-dependent pathway in gut

Arundhoti Das, Yueqiang Wang, Xiaoxiao Lu, Jonathan Kaye, Avinash Bhandoola

JOURNAL OF IMMUNOLOGY (2021)

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Meeting Abstract Hematology

Pre-Emptive Donor-Derived Innate Immune Cell Add-Back after Haploidentical Hematopoietic Stem Cell Transplantation to Reduce High Rate of Infection, Gvhd, and Non-Relapse Mortality

Noah Merin, Tu Nguyen, Jonathan Kaye, Ronald Paquette, Robert Vescio, Akil Merchant

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2020)

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Correction Medicine, Research & Experimental

Describing the dynamic translational science landscape through core voucher utilization (vol 3, pg 105, 2019)

Elvira L. Liclican, Scott G. Filler, Jonathan Kaye, Christopher T. Denny

JOURNAL OF CLINICAL AND TRANSLATIONAL SCIENCE (2020)

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Article Medicine, Research & Experimental

Describing the dynamic translational science landscape through Core Voucher utilization

Elvira L. Liclican, Scott G. Filler, Jonathan Kaye, Christopher T. Denny

JOURNAL OF CLINICAL AND TRANSLATIONAL SCIENCE (2019)

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Meeting Abstract Immunology

Development of group-3 innate lymphoid cells via Tox2-dependent pathway in gut

Arundhoti Das, Yueqiang Wang, Xiaoxiao Lu, Christelle Harly, Jonathan Kaye, Avinash Bhandoola

JOURNAL OF IMMUNOLOGY (2019)

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Meeting Abstract Oncology

Thymocyte selection-associated HMG box protein TOX is a master regulator of tumor-specific T-cell dysfunction

Andrew C. Scott, Steven Camara, Peter Lauer, Alexandra Synder, Dmitriy Zamarin, Tyler Walther, Olivier Levy, Michael Glickman, Jonathan Kaye, Mary Philip, Andrea Schietinger

CANCER IMMUNOLOGY RESEARCH (2019)

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