Genomic profiling of Sézary syndrome identifies alterations of key T cell signaling and differentiation genes

Phase 1/2 study of mogamulizumab, a defucosylated anti-CCR4 antibody, in previously treated patients with cutaneous T-cell lymphoma

(2015) M. Duvic et al.   BLOOD

Genomic landscape of cutaneous T cell lymphoma

(2015) Jaehyuk Choi et al.   NATURE GENETICS

Genomic analysis of mycosis fungoides and Sézary syndrome identifies recurrent alterations in TNFR2

(2015) Alexander Ungewickell et al.   NATURE GENETICS

Resident memory T cells in human health and disease

(2015) R. A. Clark   Science Translational Medicine

PLCG1 mutations in cutaneous T-cell lymphomas

(2014) José P. Vaqué et al.   BLOOD

Prognostic factors, prognostic indices and staging in mycosis fungoides and Sézary syndrome: where are we now?

(2014) J.J. Scarisbrick et al.   BRITISH JOURNAL OF DERMATOLOGY

Reduction of Regulatory T Cells by Mogamulizumab, a Defucosylated Anti-CC Chemokine Receptor 4 Antibody, in Patients with Aggressive/Refractory Mycosis Fungoides and Sezary Syndrome

(2014) X. Ni et al.   CLINICAL CANCER RESEARCH

CCR4 and its ligands: from bench to bedside

(2014) O. Yoshie et al.   INTERNATIONAL IMMUNOLOGY

Gain-of-functionCCR4mutations in adult T cell leukemia/lymphoma

(2014) Masao Nakagawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Novel somatic and germline mutations in intracranial germ cell tumours

(2014) Linghua Wang et al.   NATURE

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes

(2014) Robert Huether et al.   Nature Communications

IL32 Is Progressively Expressed in Mycosis Fungoides Independent of Helper T-cell 2 and Helper T-cell 9 Polarization

(2014) H. Ohmatsu et al.   Cancer Immunology Research

From human genome to cancer genome: The first decade

(2013) D. A. Wheeler et al.   GENOME RESEARCH

The Role of IL-32 in Cutaneous T-Cell Lymphoma

(2013) Hiraku Suga et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application

(2013) Taku Okazaki et al.   NATURE IMMUNOLOGY

RNA-SeQC: RNA-seq metrics for quality control and process optimization

(2012) David S. DeLuca et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

The tumour suppressor p53 is frequently nonfunctional in Sézary syndrome

(2012) B. Lamprecht et al.   BRITISH JOURNAL OF DERMATOLOGY

Long-term Outcomes of 1,263 Patients with Mycosis Fungoides and Sezary Syndrome from 1982 to 2009

(2012) R. Talpur et al.   CLINICAL CANCER RESEARCH

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

(2012) J. G. Lohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of novel transcripts in annotated genomes using RNA-Seq

(2011) A. Roberts et al.   BIOINFORMATICS

Tumor suppressor TNFAIP3 (A20) is frequently deleted in Sézary syndrome

(2011) F C M Braun et al.   LEUKEMIA

deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data

(2011) Andrew McPherson et al.   PLoS Computational Biology

Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors

(2010) J. J. Campbell et al.   BLOOD

Survival Outcomes and Prognostic Factors in Mycosis Fungoides/Sézary Syndrome: Validation of the Revised International Society for Cutaneous Lymphomas/European Organisation for Research and Treatment of Cancer Staging Proposal

(2010) Nita Sally Agar et al.   JOURNAL OF CLINICAL ONCOLOGY

CDKN2A–CDKN2B deletion defines an aggressive subset of cutaneous T-cell lymphoma

(2010) Elodie Laharanne et al.   MODERN PATHOLOGY

Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-β1-mediated growth suppression in adult T-cell leukemia/lymphoma

(2010) S Nakahata et al.   ONCOGENE

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Cutaneous lymphoma incidence patterns in the United States: a population-based study of 3884 cases

(2009) P. T. Bradford et al.   BLOOD

Identification of Key Regions and Genes Important in the Pathogenesis of Sezary Syndrome by Combining Genomic and Expression Microarrays

(2009) E. Caprini et al.   CANCER RESEARCH

Overall survival in erythrodermic cutaneous T-cell lymphoma: an analysis of prognostic factors in a cohort of patients with erythrodermic cutaneous T-cell lymphoma

(2009) Kelley A. Vidulich et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Cutaneous T-Cell Lymphoma: Roles for Chemokines and Chemokine Receptors

(2009) Xue-Song Wu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Downregulation of Fas Gene Expression in Sézary Syndrome Is Associated with Promoter Hypermethylation

(2009) Christine L. Jones et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Down-regulation of TCF8 is involved in the leukemogenesis of adult T-cell leukemia/lymphoma

(2008) T. Hidaka et al.   BLOOD

Prevalence and treatment of Staphylococcus aureus colonization in patients with mycosis fungoides and Sézary syndrome

(2008) R. Talpur et al.   BRITISH JOURNAL OF DERMATOLOGY

Novel and Highly Recurrent Chromosomal Alterations in Sezary Syndrome

(2008) M. H. Vermeer et al.   CANCER RESEARCH

The ERK-RSK1 activation by growth factors at G2 phase delays cell cycle progression and reduces mitotic aberrations

(2008) Hyun-Ja Nam et al.   CELLULAR SIGNALLING

Interleukin-32 monoclonal antibodies for Immunohistochemistry, Western blotting, and ELISA

(2008) Ki-Hong Kim et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

(2008) G. Lenz et al.   SCIENCE