Recombination affects accumulation of damaging and disease-associated mutations in human populations

The Relation between Recombination Rate and Patterns of Molecular Evolution and Variation in Drosophila melanogaster

(2014) José L. Campos et al.   MOLECULAR BIOLOGY AND EVOLUTION

The deleterious mutation load is insensitive to recent population history

(2014) Yuval B Simons et al.   NATURE GENETICS

High-Resolution Genomic Analysis of Human Mitochondrial RNA Sequence Variation

(2014) A. Hodgkinson et al.   SCIENCE

SLiM: Simulating Evolution with Selection and Linkage

(2013) Philipp W. Messer   GENETICS

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

(2013) Jing Wang et al.   NUCLEIC ACIDS RESEARCH

ClinVar: public archive of relationships among sequence variation and human phenotype

(2013) Melissa J. Landrum et al.   NUCLEIC ACIDS RESEARCH

Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics

(2013) Ekta Khurana et al.   SCIENCE

Whole-Exome Sequencing Reveals a Rapid Change in the Frequency of Rare Functional Variants in a Founding Population of Humans

(2013) Ferran Casals et al.   PLoS Genetics

The Effects of Deleterious Mutations on Evolution at Linked Sites

(2012) Brian Charlesworth   GENETICS

Molecular Evolution in Nonrecombining Regions of the Drosophila melanogaster Genome

(2012) José L. Campos et al.   Genome Biology and Evolution

Cohort profile of the CARTaGENE study: Quebec’s population-based biobank for public health and personalized genomics

(2012) Philip Awadalla et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Improved whole-chromosome phasing for disease and population genetic studies

(2012) Olivier Delaneau et al.   NATURE METHODS

An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People

(2012) M. R. Nelson et al.   SCIENCE

Recent Explosive Human Population Growth Has Resulted in an Excess of Rare Genetic Variants

(2012) A. Keinan et al.   SCIENCE

Recombination Modulates How Selection Affects Linked Sites in Drosophila

(2012) Suzanne E. McGaugh et al.   PLOS BIOLOGY

The landscape of recombination in African Americans

(2011) Anjali G. Hinch et al.   NATURE

Classic Selective Sweeps Were Rare in Recent Human Evolution

(2011) R. D. Hernandez et al.   SCIENCE

Deep Human Genealogies Reveal a Selective Advantage to Be on an Expanding Wave Front

(2011) C. Moreau et al.   SCIENCE

Natural Selection Affects Multiple Aspects of Genetic Variation at Putatively Neutral Sites across the Human Genome

(2011) Kirk E. Lohmueller et al.   PLoS Genetics

Haplotype allelic classes for detecting ongoing positive selection

(2010) Julie Hussin et al.   BMC BIOINFORMATICS

Fine-scale recombination rate differences between sexes, populations and individuals

(2010) Augustine Kong et al.   NATURE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

A flexible forward simulator for populations subject to selection and demography

(2008) R. D. Hernandez   BIOINFORMATICS

No effect of recombination on the efficacy of natural selection in primates

(2008) K. Bullaughey et al.   GENOME RESEARCH

The effects of deleterious mutations on evolution in non-recombining genomes

(2008) Vera B. Kaiser et al.   TRENDS IN GENETICS

Assessing the Evolutionary Impact of Amino Acid Mutations in the Human Genome

(2008) Adam R. Boyko et al.   PLoS Genetics