Translating the effects of mTOR on secretory senescence

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

(2015) Nicolás Herranz et al.   NATURE CELL BIOLOGY

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

(2015) Remi-Martin Laberge et al.   NATURE CELL BIOLOGY

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy

(2013) Jan R. Dörr et al.   NATURE

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence

(2012) Marina Kolesnichenko et al.   CELL CYCLE

mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis

(2012) Ramiro Iglesias-Bartolome et al.   Cell Stem Cell

A unifying model for mTORC1-mediated regulation of mRNA translation

(2012) Carson C. Thoreen et al.   NATURE

The translational landscape of mTOR signalling steers cancer initiation and metastasis

(2012) Andrew C. Hsieh et al.   NATURE

Rapamycin decelerates cellular senescence

(2011) Zoya N. Demidenko et al.   CELL CYCLE

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

(2011) Tae-Won Kang et al.   NATURE

Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes

(2011) M. Narita et al.   SCIENCE

Cell surface-bound IL-1  is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network

(2009) A. V. Orjalo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2

(2008) S. Maitra et al.   RNA