EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

A Synthetic Lethality-Based Strategy to Treat Cancers Harboring a Genetic Deficiency in the Chromatin Remodeling Factor BRG1

(2013) T. Oike et al.   CANCER RESEARCH

BAF complexes facilitate decatenation of DNA by topoisomerase IIα

(2013) Emily C. Dykhuizen et al.   NATURE

Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features

(2012) Daisuke Matsubara et al.   CANCER SCIENCE

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

(2012) Marcin Imielinski et al.   CELL

Randomized phase II study of concurrent cisplatin/etoposide or paclitaxel/carboplatin and thoracic radiotherapy in patients with stage III non-small cell lung cancer

(2012) Luhua Wang et al.   LUNG CANCER

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

(2012) Michael T. McCabe et al.   NATURE

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

(-)-Epigallocatechin-3-gallate and DZNep reduce polycomb protein level via a proteasome-dependent mechanism in skin cancer cells

(2011) S. R. Choudhury et al.   CARCINOGENESIS

ATP-dependent chromatin remodeling: genetics, genomics and mechanisms

(2011) Diana C Hargreaves et al.   CELL RESEARCH

Lung Stem Cell Self-Renewal Relies on BMI1-Dependent Control of Expression at Imprinted Loci

(2011) Sima J. Zacharek et al.   Cell Stem Cell

Epigenetic Antagonism between Polycomb and SWI/SNF Complexes during Oncogenic Transformation

(2010) Boris G. Wilson et al.   CANCER CELL

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Primary Tumor Genotype Is an Important Determinant in Identification of Lung Cancer Propagating Cells

(2010) Stephen J. Curtis et al.   Cell Stem Cell

Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling

(2010) C. M. Fillmore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PIK3CA Mutations and Copy Number Gains in Human Lung Cancers

(2008) H. Yamamoto et al.   CANCER RESEARCH

Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines

(2008) Pedro P. Medina et al.   HUMAN MUTATION

Gene expression profiling for molecular distinction and characterization of laser captured primary lung cancers

(2008) Astrid Rohrbeck et al.   Journal of Translational Medicine

Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cells: development of a molecular predictive model

(2008) A. Miyanaga et al.   MOLECULAR CANCER THERAPEUTICS

Roles of the EZH2 histone methyltransferase in cancer epigenetics

(2008) Jeffrey A. Simon et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Gene expression–based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study

(2008) Kerby Shedden et al.   NATURE MEDICINE

The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing

(2008) J. E. Deweese et al.   NUCLEIC ACIDS RESEARCH

DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers

(2008) W W Lockwood et al.   ONCOGENE

Gene Expression Signature of Cigarette Smoking and Its Role in Lung Adenocarcinoma Development and Survival

(2008) Maria Teresa Landi et al.   PLoS One

A Precisely Regulated Gene Expression Cassette Potently Modulates Metastasis and Survival in Multiple Solid Cancers

(2008) Kun Yu et al.   PLoS Genetics