Article
Chemistry, Applied
Carla de Fatima Alves Nonato, Cicera Janaine Camilo, Debora Odilia Duarte Leite, Mario Gustavo Lucio Albuquerque da Abrega, Jaime Ribeiro-Filho, Irwin Rose Alencar de Menezes, Josean Fechine Tavares, Jose Galberto Martins da Costa
Summary: This study compared the chemical composition and antioxidant potential of essential oils from the Lippia genus through chemometric analysis. The results showed that the essential oils exhibited significant antioxidant activity, with different compounds in Lippia alba being effective in various antioxidant methods. The findings highlight the importance of Lippia compounds for protecting against oxidative stress and their potential use in food preservation.
Article
Food Science & Technology
Cristina Saraiva, Ana Catarina Silva, Juan Garcia-Diez, Beniamino Cenci-Goga, Luca Grispoldi, Anibal Filipe Silva, Jose Manuel Almeida
Summary: Listeria monocytogenes is a concern in cheese making due to its ability to survive in various conditions, leading the dairy industry to seek natural additives like myrtle and rosemary essential oils as potential antimicrobial agents. The essential oils were effective at inhibiting the growth of L. monocytogenes in sheep cheese, showing potential for ensuring food safety without impacting the native microflora.
Article
Biochemistry & Molecular Biology
Seyed Mohammad Bagher Hashemi, Aliakbar Gholamhosseinpour, Francisco J. Barba
Summary: This study examined the effects of Rosmarinus officinalis L. essential oil (REO) at different concentrations on the microbiological and oxidative stability of Sarshir during refrigerated storage. The major components of REO were identified through GC/MS analysis, and antimicrobial and antioxidant properties of REO were evaluated. It was found that REO had inhibitory effects on spoilage and pathogenic bacteria, and also contributed to the oxidative stability of Sarshir.
Article
Infectious Diseases
Khadijetou Hamoud Bowbe, Karima Bel Hadj Salah, Sarra Moumni, Mada F. Ashkan, Abderrahmen Merghni
Summary: Rosemary and Myrtle essential oils have antibacterial and antibiofilm effects, and can inhibit the virulence of Staphylococcus aureus. The efficacy of the oils against the bacteria depends on their concentration.
Article
Agricultural Engineering
Elaissi Ameur, Moumni Essahli Sarra, Khtatfa Takoua, Kouja Mariem, Abid Nabil, Frederic Lynen, Khouja Mohamed Larbi
Summary: This study investigated the chemical composition and antibacterial activity of Pinus essential oils from five Tunisian species, finding that blends of oils extracted from certain species showed the highest antibacterial activity. These oil blends may serve as promising alternatives for the treatment of otitis media.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Biochemistry & Molecular Biology
Ceyda S. Kilic, Betul Demirci, Damla Kirci, Hayri Duman, Ilhan Gurbuz
Summary: This study investigated the essential oil compositions of Ferulago glareosa roots and aerial parts for the first time and compared them with other species of the genus. The major components of the root essential oil were 2,3,6-trimethylbenzaldehyde, falcarinol, hexadecanoic acid, and 2,5-dimethoxy-p-cymene, while the major components of the aerial part essential oil were alpha-pinene, p-cymene, gamma-terpinene, (Z)-beta-ocimene, and terpinolene. The composition of F. glareosa root essential oil differed greatly from other species in the literature.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Infectious Diseases
Ylenia Pieracci, Daniela Ciccarelli, Silvia Giovanelli, Luisa Pistelli, Guido Flamini, Claudio Cervelli, Francesca Mancianti, Simona Nardoni, Fabrizio Bertelloni, Valentina Virginia Ebani
Summary: This study investigated the chemical profile, extraction yield, antibacterial, and antifungal activities of essential oils obtained from different cultivars of Salvia rosmarinus and Salvia jordanii. Results showed variations in chemical composition and activities among different cultivars.
Review
Agronomy
Nikola Puvaca, Vincenzo Tufarelli, Ilias Giannenas
Summary: The use of essential oils as a substitute for antibiotic growth promoters in animal nutrition, specifically in broiler nutrition, has gained attention. The efficacy of essential oils varies depending on factors such as dietary composition, feed inclusion level, and bird genetics. Despite limited information on the effects of essential oils on nutrient digestibility, gut function, and the immune system, research supports their potential use as natural growth promoters for broilers.
Article
Plant Sciences
Amal Ramzi, Abdelhakim El Ouali Lalami, Yassine Ez Zoubi, Amine Assouguem, Rafa Almeer, Agnieszka Najda, Riaz Ullah, Sezai Ercisli, Abdellah Farah
Summary: This study investigates the insecticidal effect of Mentha pulegium and Rosmarinus officinalis essential oils and their major compounds on Culex pipiens mosquitoes. The findings suggest that these plant extracts have better insecticidal effects than chemical insecticides and can potentially be used as eco-friendly alternatives in vector management.
Article
Chemistry, Applied
Imane Oualdi, Khaoula Diass, Salah-Eddine Azizi, Mohammed Dalli, Rachid Touzani, Nadia Gseyra, El Bekkaye Yousfi
Summary: This study extracted essential oils from two cities in the eastern region of Morocco and determined their chemical composition using GC/MS. The antioxidant activity of the oils was also assessed.
NATURAL PRODUCT RESEARCH
(2023)
Article
Agricultural Engineering
Sara El Kharraf, Soukaina El-Guendouz, Abdellah Farah, Bahia Bennani, Maria C. Mateus, El Mestafa El Hadrami, M. Graca Miguel
Summary: This study aimed to investigate the antibacterial activities of two essential oils against multiple bacteria, and the results showed that essential oils obtained by simultaneous extraction had better antimicrobial and antioxidant activities.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Agricultural Engineering
Ylenia Pieracci, Flavia Fulvio, Valeria Isca, Luisa Pistelli, Laura Bassolino, Massimo Montanari, Anna Moschella, Guido Flamini, Roberta Paris
Summary: The inflorescences of Cannabis sativa L. are a valuable by-product of industrial hemp cultivation, and the volatile fraction of these inflorescences has attracted attention for its applications in various fields. This study investigated the effect of phenological stage on the chemical composition and hydro-distillation yield of hemp-derived essential oil (EO). Two hemp varieties, Codimono (monoecious) and Fibrante (dioecious), were cultivated, and the flowering tops were collected at different stages. Analysis of the EO revealed that terpenes and phyto-cannabinoids were the major chemical classes, with sesquiterpene hydrocarbons being the most abundant components. The EO yield increased with phenological development, reaching its highest rate at seed harvest time.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Food Science & Technology
Paulina Olivas-Mendez, America Chavez-Martinez, Eduardo Santellano-Estrada, Luis Guerrero Asorey, Rogelio Sanchez-Vega, Ana Luisa Renteria-Monterrubio, David Chavez-Flores, Juan Manuel Tirado-Gallegos, Gerardo Mendez-Zamora
Summary: The inclusion of natural ingredients such as rosemary and garlic essential oils, as well as chipotle pepper oleoresin, has been found to effectively preserve beef hamburgers by inhibiting microbial growth and lipid oxidation. Consumers preferred hamburgers with added garlic essential oil in terms of sensory attributes.
Article
Chemistry, Applied
Fatima Zohra Guellouma, Hadjer Boussoussa, Ihcen Khachba, Mohamed Yousfi, Ibtissem Ziane Khoudja, Ibrahim Bourahla
Summary: Antibiotics are becoming less effective in treating bacterial resistance, especially in hospitals. However, there is a growing interest in exploring secondary metabolites, particularly for treating multidrug-resistant clinical diseases. This study evaluated the effectiveness of Rosmarinus officinalis essential oil against several resistant bacterial pathogens, and the results showed promising antibacterial activity. This suggests that Rosmarinus essential oil has the potential to be used as a therapeutic agent against a wide range of multidrug-resistant bacteria.
NATURAL PRODUCT RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Naglaa S. Ashmawy, Haidy A. Gad, Heba A. S. El-Nashar
Summary: This study compares the chemical compositions of essential oils isolated from different organs of Syzygium cumini and explores their similarities and differences using chemometric analysis. The study also finds that Scl and Scs oils show superior anti-aging activities.
Review
Chemistry, Applied
Eleonora Di Salvo, Francesca Conte, Marco Casciaro, Sebastiano Gangemi, Nicola Cicero
Summary: Mammalian milk contains various components that have chemical and functional activities, which positively impact human health. In addition to their nutritional value, the biologically active compounds in milk play important roles in physiological and biochemical functions in the human body. Donkey and camel milk contain bioactive molecules that have the potential to benefit human health.
NATURAL PRODUCT RESEARCH
(2023)
Article
Chemistry, Applied
Sara Vitalini, Luca Nalbone, Cristian Bernardi, Marcello Iriti, Rosaria Costa, Nicola Cicero, Filippo Giarratana, Lisa Vallone
Summary: This study evaluated the chemical composition and in vitro antimicrobial activity of store-bought parsley and ginger essential oils. Parsley essential oil showed the best compromise between sensory influence and antimicrobial activity. It effectively prevented the growth of A. flavus in cheese.
NATURAL PRODUCT RESEARCH
(2023)
Article
Chemistry, Applied
Luca Gammeri, Claudia Panzera, Fabrizio Calapai, Nicola Cicero, Sebastiano Gangemi
Summary: Chronic urticaria is a pathological condition characterized by wheals and angioedema lasting for more than six weeks. Treatment commonly involves antihistamines, but corticosteroids and monoclonal antibodies can also be used. Herbal medicine is an alternative approach, with some herbs possessing anti-inflammatory, anti-allergic, and antioxidant properties.
NATURAL PRODUCT RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Monika Hofbauerova, Magdalena Ruskova, Andrea Puskarova, Maria Buckova, Adriana Annusova, Eva Majkova, Peter Siffalovic, Giuseppe Granata, Edoardo Napoli, Corrada Geraci, Domenico Pangallo
Summary: The colonization of building materials by microorganisms is a major cause of degradation, posing health risks from fungal and bacterial products. The study evaluated the efficacy of oregano and thyme essential oils encapsulated in nanocapsules for protection and disinfection against various microorganisms. The results showed that these nanocapsules effectively disinfect and inhibit biofilm formation without causing visible color changes in the materials.
Article
Biochemistry & Molecular Biology
Eleonora Di Salvo, Marco Casciaro, Concetto Mario Giorgianni, Nicola Cicero, Sebastiano Gangemi
Summary: Aging is a natural process that affects all living beings, leading to a decline in their ability to adapt to external changes. Oxidative stress, particularly from halogen compounds like chloride, plays a significant role in this process.
Review
Biochemistry & Molecular Biology
Lucia Peterle, Serena Sanfilippo, Francesco Borgia, Nicola Cicero, Sebastiano Gangemi
Summary: Alopecia areata is characterized by non-scarring hair loss and oxidative stress plays an important role in its pathogenesis. Oxidative stress markers are altered in patients with alopecia areata, indicating a pro-oxidative status. Oxidative stress induces the destabilization of the hair follicle immune-privileged site through the activation of MICA and NKG2D receptors. In addition, autophagy is reduced during the progression of alopecia areata. Potential biomarkers of oxidative stress in alopecia areata include MDA, AGEs, and IMA. JAK inhibitors and nutraceuticals that modulate oxidative stress balance show promise as therapeutic tools.
Review
Biochemistry & Molecular Biology
Alessandro Allegra, Nicola Cicero, Giuseppe Mirabile, Concetto Mario Giorgianni, Sebastiano Gangemi
Summary: Lower-than-normal platelet counts are a hallmark of immune thrombocytopenia, an acquired autoimmune illness. The lack of a valid biomarker or gold-standard diagnostic test leads to high rates of misdiagnosis. Recent studies have revealed various factors involved in the disease's etiology, such as immune-activating substances and genetic mutations. This review aims to compile information on novel biomarkers for immune thrombocytopenia to enhance patient management.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Applied
Vita Di Stefano, Nicola Cicero, Maria Grazia Melilli, Enrico Ganguzza, Massimo Lucarini, Alessandra Durazzo
Summary: Quality control is crucial for protein supplements aimed at a large consumer base like sportspeople. A study analyzed 16 sports supplements from various European countries and found discrepancies in amino acid quantities compared to the label. Some samples exceeded the maximum tolerance regulated by the European Commission, while others had amino acid concentrations exceeding the analytical tolerance percentage. However, essential and branched amino acid supplements were found to conform to the declared quantities.
NATURAL PRODUCT RESEARCH
(2023)
Article
Nutrition & Dietetics
Mariarosaria Ingegneri, Antonella Smeriglio, Rossana Rando, Teresa Gervasi, Maria Pia Tamburello, Giovanna Ginestra, Erminia La Camera, Rosamaria Pennisi, Maria Teresa Sciortino, Giuseppina Mandalari, Domenico Trombetta
Summary: This study investigated the nutritional and polyphenolic profile, as well as the antioxidant, antimicrobial, antiviral, and potential prebiotic effects of blanched almond skin (BS) and blanch water (BW) from three different Sicilian cultivars. The results showed that the total phenols and flavonoids contents were high in BS and BW. BS exhibited antiviral activity against herpes simplex virus 1. It also had high fiber and protein contents and low fat and sugar contents, making it nutritionally valuable. The study indicated that cultivar does not significantly affect the chemical and biological properties of BS and BW.
Editorial Material
Chemistry, Multidisciplinary
Teresa Gervasi
APPLIED SCIENCES-BASEL
(2023)
Review
Biology
Santino Caserta, Claudia Genovese, Nicola Cicero, Sebastiano Gangemi, Alessandro Allegra
Summary: Cinnamon, a plant that grows in Sri Lanka, has been tested in various studies for its potential anticancer effect. The studies have shown that cinnamon extract can regulate cellular pathways and inhibit the activity of molecules that promote cell proliferation and survival. It can also enhance the immune response against tumors. More research is needed to fully understand the potential of cinnamon extract in cancer treatment.
Article
Chemistry, Applied
Giovanna Loredana La Torre, Rossella Vadala, Nicola Cicero, Giovanni Lo Cascio, Antonello Cicero, Vittorio Calabrese, Vincenzo Ferrantelli, Cinzia Ingallina, Andrea Salvo
Summary: This study investigated the impact of a new bio-packaging on histamine formation in mackerel for the first time. A treatment with innovative polymeric film and a soaking procedure in liquid new biomaterial were adopted to monitor the preservation of fresh fish samples. Ultra HPLC diode array detection (UHPLC-DAD) analyses showed that histamine levels were affected by application of biomaterial after 7 days. The new biofilm extended the shelf-life and showed potential in preventing histamine biosynthesis.
NATURAL PRODUCT RESEARCH
(2023)
Article
Chemistry, Applied
Clara Naccari, Nicola Cicero, Rossella Vadala, Giovanni Bartolomeo, Ernesto Palma
Summary: The agro-food surplus is a valuable renewable resource with economic and environmental impact. Before using agro-food wastes, toxicological analysis is necessary to prevent potential risks. This study evaluated the metals content in agro-food wastes and found that most of them can be safely reused, especially as animal feed supplements.
NATURAL PRODUCT RESEARCH
(2023)
Review
Nutrition & Dietetics
Santino Caserta, Claudia Genovese, Nicola Cicero, Valeria Toscano, Sebastiano Gangemi, Alessandro Allegra
Summary: The gut microbiota, a community of bacteria in the gastrointestinal tract, undergoes changes in response to various factors such as diseases, diet, antibiotics, and probiotics. Dysbiosis, characterized by altered communication between the host and the microbes, is associated with obesity, diabetes, cancer, and cardiovascular diseases. Certain plants have been shown to have anticancer properties and the ability to modulate the gut microbiota. This review highlights the potential use of medicinal plants in improving gut dysbiosis and aiding cancer treatment.
Article
Environmental Sciences
Eleonora Di Salvo, Roberta Tardugno, Vincenzo Nava, Clara Naccari, Antonio Virga, Andrea Salvo, Filomena Corbo, Maria Lisa Clodoveo, Nicola Cicero
Summary: The concentration of mineral elements in 10 different commercially available salts in southern Italy varied according to their type and geographical origin. Some salts showed elevated levels of certain elements such as iron and zinc, which could be beneficial in specific conditions, however, nickel levels were high in certain salts and lead exceeded the maximum level in all samples. Additional monitoring of mineral contents in table salts is recommended for human health.