Article
Food Science & Technology
Bingxin Yang, Sheng Wang, Wen Ma, Guanlin Li, Mengling Tu, Zhiyong Ma, Qinghe Zhang, Hongmei Li, Xianjiang Li
Summary: This research developed and validated a modified QuEChERS method combined with ultra-performance liquid chromatography-tandem mass spectrometry to determine pesticide residues in freeze-dried cabbage. The method achieved acceptable validation results with low limits of quantification and good recovery rates. The developed method was applied to real freeze-dried cabbages and detected four pesticides in the samples.
Article
Food Science & Technology
Thammaporn Junsai, Saranya Poapolathep, Samak Sutjarit, Mario Giorgi, Zhaowei Zhang, Antonio Francesco Logrieco, Peiwu Li, Amnart Poapolathep
Summary: This study investigated the occurrence of multi-mycotoxins in six types of vegetable oils available in Thailand, revealing variations in mycotoxin contamination among different oil samples. The levels of analyzed mycotoxins were found to be below regulatory limits, indicating a low health risk to consumers.
Article
Food Science & Technology
Hongping Chen, Xinlu Wang, Pingxiang Liu, Qi Jia, Haolei Han, Changling Jiang, Jing Qiu
Summary: A modified QuEChERS method using ultra performance liquid chromatography tandem mass spectrometry was developed for the determination of three typical metabolites of pyrethroid pesticides in tea. The method was validated with good accuracy and precision, and 3-PBA and TFA were detected in two out of 22 tea samples.
Article
Chemistry, Applied
Cristopher Dominguez-Hernandez, Cecilia Ortega-Zamora, Javier Gonzalez-Salamo, Javier Hernandez-Borges
Summary: The QuEChERS method was successfully applied to extract a group of esters from coffee, and the results showed good linearity and accuracy. The study also found that for most of the analyzed components, the relative recovery values were in the range of 70-120%.
Article
Chemistry, Applied
Annalisa Sambolino, Cecilia Ortega-Zamora, Javier Gonzalez-Salamo, Ana Dinis, Nereida Cordeiro, Joao Canning-Clode, Javier Hernandez-Borges
Summary: In this study, the ammonium formate version of the QuEChERS method was used for the first time to extract a group of phthalic acid esters and one adipate from fish and squid samples. The method was validated and found to be effective for the extraction and determination of the target compounds.
Article
Food Science & Technology
Jiali Xing, Zigeng Zhang, Ruihang Zheng, Xiaorong Xu, Lingyan Mao, Jingping Lu, Jian Shen, Xianjun Dai, Zhenfeng Yang
Summary: A novel and rapid method was established for the simultaneous detection of seven Alternaria toxins in mixed fruit purees, with results showing the presence of toxins in 31 out of 80 samples with a wide range of contamination levels. This method provides a practical tool for the determination of Alternaria toxins in fruit puree samples and could serve as a foundation for establishing limit standards and developing similar detection methods in the future.
Article
Biochemistry & Molecular Biology
Magdalena Slowik-Borowiec, Ewa Szpyrka, Paulina Ksiazek-Trela, Magdalena Podbielska
Summary: New analytical approaches were developed for the identification and quantification of pesticides and PAHs in five representative matrices. The optimized procedure showed satisfactory results for all analytes, with improved recovery and precision. The method was successfully applied to determine pesticide residues in commercial samples and showed potential for reducing sample preparation time and solvent consumption.
Article
Chemistry, Analytical
Bernhard Thalhamer, Armin Sebastian Guntner, Wolfgang Buchberger
Summary: A rapid and reliable method for detecting quaternary ammonium cation and halide anion in a single analytical run was developed using gas chromatography mass spectrometry (GC/MS). The method allows for the determination of both the cation and anion in disinfectants within seven minutes. The study revealed clear differences in biocidal activity, toxicity, and allergic potential among different halide anions and quaternary ammonium cations.
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
(2022)
Article
Food Science & Technology
Shuo Li, Can Zhang, Hui-Xin Tang, Yue Gu, Ai-Jing Guo, Ke Wang, Kao-Qi Lian
Summary: An effective method was developed for simultaneous determination of 24 sulfonamide antibiotics in two instant pastries. The method showed good recoveries and low variations with LODs and LOQs ranging from 0.01-0.14 mg/kg and 0.02-0.45 mg/kg, respectively. This method is suitable for analysis of sulfonamide antibiotics in instant pastries.
JOURNAL OF FOOD AND DRUG ANALYSIS
(2023)
Article
Medicine, Legal
Yujin Natori, Shoki Kamioka, Takashi Yoshimoto, Akira Ishii
Summary: Aconitum, a highly toxic plant, contains alkaloids such as aconitine, hypaconitine, jesaconitine, and mesaconitine, which can cause fatal intoxication when ingested. It is crucial to analyze these alkaloids and their metabolites in the blood. This study employed QuEChERS extraction and liquid chromatography-tandem mass spectrometry to evaluate aconitines and their metabolites in postmortem blood samples. The findings suggest that aconitine and jesaconitine accumulate in the right atrium blood after death, and the right atrium specimen is suitable for measuring aconitine compounds in fatal intoxication cases.
FORENSIC SCIENCE INTERNATIONAL
(2022)
Article
Chemistry, Analytical
Sophie Catanese, Raoul K. Khanna, Antoine Lefevre, Hugo Alarcan, Pierre-Jean Pisella, Patrick Emond, Helene Blasco
Summary: To apply metabo-lipidomics in ophthalmological and systemic diseases, it is necessary to standardize the preanalytical and analytical steps in human tears. This study compared different methods for each step of the workflow and found that methanol/water extraction provided the best results for metabolomics, while Folch extraction was superior for lipidomics. The use of microcapillary glass tube for sampling was superior to Schirmer strip for metabolomics. A volume of 5 mu L provided satisfactory metabo-lipidomic coverage. These findings will contribute to improving the metabo-lipidomic workflow in human tears for the identification of new biomarkers.
Article
Environmental Sciences
A. Ruth Godfrey, Jonathan Dunscombe, Anthony Gravell, Ann Hunter, Mark P. Barrow, Geertje van Keulen, Claire Desbrow, Rachel Townsend
Summary: The study demonstrates that the modified QuEChERS sample preparation method is a viable option for efficient and cost-effective monitoring of environmental pollutants. The method offers reduced extraction times, good reproducibility, and the ability to differentiate between different samples. It also identifies new potential pollutant candidates.
Article
Chemistry, Analytical
Slavka Nagyova, Peter Tolgyessy, Milan Laurencik, Michal Kirchner
Summary: The study introduced a new sample preparation method combined with gas chromatography-triple quadrupole tandem mass spectrometry for determining polycyclic aromatic hydrocarbons in dried gammarid samples. The method showed high sensitivity, precision, and recovery rates, making it suitable for monitoring and controlling compliance with environmental quality standards for specific PAHs in surface water biota.
MICROCHEMICAL JOURNAL
(2022)
Article
Environmental Sciences
Kai Jansen, Christian Mohr, Katrin Luegger, Christian Heller, Jan Siemens, Ines Mulder
Summary: Quaternary alkylammonium compounds (QAACs) are widely used as surfactants and disinfectants in various industries. Studies suggest that QAACs may contribute to the spread of antibiotic resistance in the environment. A comprehensive study conducted in German soils found QAACs in 97% of the samples, with long-chain DADMACs being the most abundant.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Analytical
Dan Fei, Mengzhi Wang, Yujie Hou, Min Xie, Yaomin Zhou, Youhua Zhao, Lei Wu, Jun Xu
Summary: The study presented a rapid and reliable method for simultaneous determination of organophosphorus pesticides in porcine hair, with linear relationships between 1.0 to 100 µg/kg and high accuracy and precision.
ANALYTICAL LETTERS
(2022)
Review
Food Science & Technology
Araceli Rivera-Perez, Roberto Romero-Gonzalez, Antonia Garrido Frenich
Summary: This review examines the extraction and clean-up procedures for toxic compounds in spices, herbs, and tea from 2010 to 2020. Analytical methods, including chromatographic separation and mass spectrometry detection, are discussed. The occurrence of these compounds in different matrices is also summarized.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Julia Baranzelli, Sabrina Somacal, Camila Sant'Anna Monteiro, Renius de Oliveira Mello, Eliseu Rodrigues, Osmar Damian Prestes, Rosalia Lopez-Ruiz, Antonia Garrido Frenich, Roberto Romero-Gonzalez, Martha Zavariz de Miranda, Tatiana Emanuelli
Summary: Pre-harvest sprouting in wheat can be simulated in the laboratory, and different wheat cultivars have distinct behavior in terms of changes in phytochemical compounds during germination. Hard wheat cultivars have higher contents of benzoxazinoids and flavonoids compared to soft wheat cultivars. The matrix-bound phytochemicals decrease only in hard-texture wheat cultivars during germination, due to decreased levels of phenolic acids and flavonoids that are bound to the cell wall. Germination also increases the content of benzoxazinoids and antioxidant capacity in wheat, enhancing its health benefits.
Review
Chemistry, Analytical
Jesus Marin-Saez, Rosalia Lopez-Ruiz, Madalena Sobral, Roberto Romero-Gonzalez, Antonia Garrido Frenich, Isabel M. P. L. V. O. Ferreira
Summary: This study conducted a systematic review of literature from January 1, 2000 to March 15, 2022, focusing on studies related to the analysis of organic chemical hazards in saliva. The review aimed to provide insights into saliva sample collection, extraction, and analytical techniques, as well as the presence of identified compounds. The findings identified significant gaps in the standardized procedures for saliva sampling/collection/storage, limiting the wider use of saliva as a valuable specimen for human biomonitoring of exposure to food chain contaminants.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Food Science & Technology
Maria Elena Hergueta-Castillo, Rosalia Lopez-Ruiz, Antonia Garrido Frenich, Roberto Romero-Gonzalez
Summary: This study evaluated the metabolism and dissipation of flutriafol in different conditions and found that it had a short half-life of less than 17 days. Seven metabolites were detected at low concentrations, and some of them were found to be more toxic than the parent compound.
Article
Chemistry, Applied
Araceli Rivera-Perez, Pascual Garcia-Perez, Roberto Romero-Gonzalez, Antonia Garrido Frenich, Luigi Lucini
Summary: A comprehensive UHPLC-QTOF-HRMS fingerprinting approach was used to trace thyme from three different production regions and evaluate the metabolic differences in response to processing. 37 key compounds related to origin and 33 key compounds related to processing differentiation were identified. The study highlights the terroir influence on thyme composition, with flavonoids, amino acids, and peptides being the most discriminant chemical classes. Thyme sterilization was found to enrich the overall metabolite content, potentially due to increased compound accessibility.
Article
Agriculture, Multidisciplinary
Jesus Marin-Saez, Rosalia Lopez-Ruiz, Roberto Romero-Gonzalez, Antonia Garrido Frenich
Summary: In this study, a method involving solid-liquid extraction and liquid chromatography-high-resolution mass spectrometry was developed to investigate the dissipation of neem oil when applied alone or together with Bacillus thuringiensis (Bt). The dissipation of azadirachtin A (AzA) was found to be faster when neem oil and Bt were applied together at 22 degrees C compared to when neem oil was applied alone at 3 degrees C. Several related compounds and unknown metabolites were also identified in the degraded samples.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Antonio Jesus Maldonado-Reina, Rosalia Lopez-Ruiz, Jesus Marin Saez, Roberto Romero-Gonzalez, Patricia Marin-Membrive, Antonia Garrido-Frenich
Summary: The dissipation of chlorantraniliprole insecticide in tomatoes treated with Altacor 35 WG was studied in laboratory and greenhouse conditions, and suspect screening analysis was performed to identify transformation products and coformulants. Analyses using UHPLC-Q-Orbitrap-MS and GC-Q-Orbitrap-MS showed that chlorantraniliprole followed a biphasic kinetic model with R2 values greater than 0.99. Dissipation was faster in greenhouse studies, with 96% achieved over 53 days. One transformation product (IN-F6L99) was tentatively identified in both laboratory and greenhouse studies, and 15 volatile coformulants were identified by GC-Q-Orbitrap-MS.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Chemistry, Analytical
Rosalia Lopez-Ruiz, Antonio Jesus Maldonado-Reina, Jesus Marin-Saez, Roberto Romero-Gonzalez, Jose Luis Martinez-Vidal, Antonia Garrido Frenich
Summary: This study proposes a methodology for characterizing plant protection products (PPPs) through suspect and unknown analyses. It involves three main stages: sample preparation, separation and detection, and data analysis. The use of different solvents and chromatographic techniques, such as LC and GC coupled with HRMS analyzers, allows for accurate detection and a high number of features. Tips and recommendations for data analysis are provided to perform suspect screening and unknown analysis.
TRENDS IN ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2023)
Article
Food Science & Technology
Mireya Granados-Povedano, Irene Dominguez, Francisco Egea-Gonzalez, Antonia Garrido Frenich, Francisco Javier Arrebola
Summary: A new polyvalent wide-scope analytical method has been developed and validated to detect low concentrations of 260 pesticides, non-target substances, and metabolites in both raw and processed fruits. The target approach was validated according to SANTE Guide requirements, showing satisfactory results in terms of accuracy, precision, linearity, and robustness. The method, based on QuEChERS extraction followed by GC-HRMS, achieved part-per-trillions lower limits, allowing the detection of 18 pesticides in commercial samples. An optimized non-target approach was also applied, leading to the identification of additional compounds, including pesticide metabolites not considered in the target screening.
Article
Engineering, Marine
Marina Astudillo-Pascual, Roxana Tudor, Irene Dominguez, Pedro A. Aguilera, Antonia Garrido Frenich
Summary: This study aims to fill the information gaps regarding the content of organic micropollutants in seagrass and proposes an eco-friendly extraction method. The study conducted trials with various extraction methods and used gas chromatography coupled to high resolution mass spectrometry for comprehensive analysis. The results identified several compounds with high detection frequency in environmental samples, including PAHs, PAH derivatives, UV stabilizers, plastic additives, and pesticides.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2023)
Article
Biochemical Research Methods
Ana M. Jimenez-Carvelo, Rosalia Lopez-Ruiz, Roberto Romero-Gonzalez, Antonia Garrido-Frenich
Summary: The study shows that employing an experimental design tool facilitates rapid optimization of critical parameters in mass spectrometry. It also highlights the disadvantage of using commercial databases in compound identification and the superiority of home-made databases.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Beatriz Martin-Garcia, Roberto Romero-Gonzalez, Jose Luis Martinez Vidal, Antonia Garrido Frenich
Summary: A stationary reversed phase based on polyhydroxy methacrylate was used to determine coformulants in 20 plant protection products (PPPs) by liquid chromatography coupled to Q-Orbitrap high-resolution mass spectrometry. A total of 92 coformulants were tentatively identified, with 12 of them quantified by analytical standards. The study found that the polyhydroxy methacrylate-based stationary phase increased the identification of new coformulants in PPPs, complementing conventional C18. This strategy could be applied in future studies to estimate potential coformulant residues from PPPs applied to crops.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Jesus Marin-Saez, Rosalia Lopez-Ruiz, Roberto Romero-Gonzalez, Antonia Garrido Frenich
Summary: This study conducted targeted and nontargeted analysis to investigate the fate of additives in tomato samples treated with two pesticides under greenhouse conditions. Most of the compounds detected degraded within 7 days after the second application.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Review
Chemistry, Analytical
Rosalia Lopez-Ruiz, Jesus Marin-Saez, Osmar D. Prestes, Roberto Romero-Gonzalez, Antonia Garrido Frenich
Summary: This paper discusses the methods for controlling anthropogenic contaminants in edible oils, including sample preparation, analysis, and regulations. Liquid-liquid extraction and QuEChERS methods are commonly used for extraction and analysis, with mass spectrometry being the most commonly used analyzer. The results show that a portion of the analyzed samples exceed the legal limits for pesticides, MCPDs, and PAHs.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)