An engineered HIV-1 gp41 trimeric coiled coil with increased stability and anti-HIV-1 activity: implication for developing anti-HIV microbicides

Preclinical Evaluation of the HIV-1 Fusion Inhibitor L'644 as a Potential Candidate Microbicide

(2012) Sarah Harman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

HIV-1 variants with a single-point mutation in the gp41 pocket region exhibiting different susceptibility to HIV fusion inhibitors with pocket- or membrane-binding domain

(2012) Lu Lu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Efficacy, Stability, and Biosafety of Sifuvirtide Gel as a Microbicide Candidate against HIV-1

(2012) Liangzhu Li et al.   PLoS One

Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy

(2011) Alex Sigal et al.   NATURE

HIV-1 gp41 Core with Exposed Membrane-Proximal External Region Inducing Broad HIV-1 Neutralizing Antibodies

(2011) Ji Wang et al.   PLoS One

SHIV-162P3 Infection of Rhesus Macaques Given Maraviroc Gel Vaginally Does Not Involve Resistant Viruses

(2011) Athe M. N. Tsibris et al.   PLoS One

3-Hydroxyphthalic Anhydride-Modified Chicken Ovalbumin Exhibits Potent and Broad Anti-HIV-1 Activity: a Potential Microbicide for Preventing Sexual Transmission of HIV-1

(2010) L. Li et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel Recombinant Engineered gp41 N-terminal Heptad Repeat Trimers and Their Potential as Anti-HIV-1 Therapeutics or Microbicides

(2010) Xi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protection of Rhesus Macaques from Vaginal Infection by Vaginally Delivered Maraviroc, an Inhibitor of HIV‐1 Entry via the CCR5 Co‐Receptor

(2010) Ronald S. Veazey et al.   JOURNAL OF INFECTIOUS DISEASES

Identification of a gp41 Core-Binding Molecule with Homologous Sequence of Human TNNI3K-Like Protein as a Novel Human Immunodeficiency Virus Type 1 Entry Inhibitor

(2010) Y. Zhu et al.   JOURNAL OF VIROLOGY

In Vitro and Ex Vivo Testing of Tenofovir Shows It Is Effective As an HIV-1 Microbicide

(2010) Lisa C. Rohan et al.   PLoS One

Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic

(2010) G. H. Bird et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maleic anhydride-modified chicken ovalbumin as an effective and inexpensive anti-HIV microbicide candidate for prevention of HIV sexual transmission

(2010) Lin Li et al.   Retrovirology

Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women

(2010) Q. Abdool Karim et al.   SCIENCE

Vaginal Drug Delivery Systems for HIV Prevention

(2009) Lisa Cencia Rohan et al.   AAPS Journal

Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women

(2009) Annalene M Nel et al.   AIDS

Microbicides for HIV prevention: reality or hope?

(2009) Ian McGowan   CURRENT OPINION IN INFECTIOUS DISEASES

No Increase in Cervicovaginal Proinflammatory Cytokines After Carraguard Use in a Placebo-Controlled Randomized Clinical Trial

(2009) Liesbeth JM Bollen et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

NMR Structure of a Monomeric Intermediate on the Evolutionarily Optimized Assembly Pathway of a Small Trimerization Domain

(2009) Judith Habazettl et al.   JOURNAL OF MOLECULAR BIOLOGY

Combinations of the First and Next Generations of Human Immunodeficiency Virus (HIV) Fusion Inhibitors Exhibit a Highly Potent Synergistic Effect against Enfuvirtide- Sensitive and -Resistant HIV Type 1 Strains

(2009) C. Pan et al.   JOURNAL OF VIROLOGY

Understanding Basic Mechanisms and Optimizing Assays to Evaluate the Efficacy of Vaginal Microbicides

(2009) Marla J. Keller et al.   SEXUALLY TRANSMITTED DISEASES

Lack of Effectiveness of Cellulose Sulfate Gel for the Prevention of Vaginal HIV Transmission

(2008) Lut Van Damme et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preclinical evaluation of lime juice as a topical microbicide candidate

(2008) Patricia S Fletcher et al.   Retrovirology

Aqueous extracts from peppermint, sage and lemon balm leaves display potent anti-HIV-1 activity by increasing the virion density

(2008) Silvia Geuenich et al.   Retrovirology