Article
Chemistry, Analytical
Mejra Bektasevic, Mladenka Jurin, Marin Roje, Olivera Politeo
Summary: Bioactive compounds from plants are important in slowing neurodegenerative diseases, such as Alzheimer's disease, by inhibiting cholinesterase enzymes. Oxidative stress is associated with the development of Alzheimer's disease. The chemical composition and biological activity of the essential oil and extracts of Teucrium montanum were studied.
Article
Food Science & Technology
Zhili Ma, Yu Ma, Yin Liu, Bei Zhou, Yalin Zhao, Ping Wu, Dexin Zhang, Deyuan Li
Summary: In this study, lotus leaves were processed into tea products using different methods, and the volatile compounds, phytochemical profiles, and antioxidant activities of the teas were investigated. The mature lotus-leaf tea had more volatile compounds compared to the tender lotus-leaf tea. The white-tea process resulted in a higher amount of aroma components. Various phenolic compounds were identified in the lotus-leaf tea, and the green-tea process on mature leaves showed the highest levels of total phenolic and flavonoid compounds. The lotus-leaf teas exhibited positive antioxidant activities, with the tender leaves processed using the green-tea method showing the strongest activity. The antioxidant activities were positively correlated with the levels of total phenolic and flavonoid compounds in the teas. These findings provide a basis for producing lotus-leaf teas with desirable flavor and health benefits.
Article
Plant Sciences
Melissa Salinas, James Calva, Luis Cartuche, Eduardo Valarezo, Chabaco Armijos
Summary: The aim of this study was to extract and identify the chemical compounds of Diplosthephium juniperinum essential oil (EO) from Ecuador and to assess its anticholinesterase and antioxidant properties. The EO was found to have a moderate inhibitory effect on AChE and BuChE enzymes, as well as a lower antioxidant potential. This is the first report on the chemical composition and biological activities of the EO from D. juniperinum.
Article
Biochemistry & Molecular Biology
Jiayi Zhao, Ziyue Xu, Peizhong Gao, Xu Liu
Summary: The present study investigated the essential oil composition and biological effects of Liparis nervosa grown in China, including antioxidant and acetylcholinesterase inhibitory activities. The essential oil was rich in various compounds, with methyl (9E,11E)-octadeca-9,11-dienoate being the most abundant. The essential oil exhibited moderate antioxidant capacity and showed potential as an acetylcholinesterase inhibitor. This study provides valuable insights into the chemical composition and potential uses of L. nervosa essential oil.
Article
Biochemistry & Molecular Biology
Shaza H. Aly, Omayma A. Eldahshan, Sara T. Al-Rashood, Faizah A. Binjubair, Mahmoud A. El Hassab, Wagdy M. Eldehna, Stefano Dall'Acqua, Gokhan Zengin
Summary: The chemical compositions and potential activities of Psidium guajava (Guava tree) were investigated in this study. The results showed that the extracts and essential oil of Guava tree have potential antioxidant and enzyme inhibitory properties, suggesting their potential use in the treatment of oxidative stress, neurodegenerative diseases, and diabetes mellitus.
Article
Biochemistry & Molecular Biology
Fan Su, Gan Yang, Datong Hu, Chen Ruan, Jing Wang, Yingying Zhang, Qingjun Zhu
Summary: This study analyzed the chemical composition of Centipeda minima essential oil (EOCM) using GC-MS, and found that the main constituents were trans-chrysanthenyl acetate, thymol, aromadendrene, and beta-caryophyllene. The antibacterial screening revealed that thymol and carvacrol, two monomers in EOCM, exhibited antibacterial activity against S. aureus. The minimum inhibitory concentrations (MIC) of EOCM, thymol, and carvacrol were 0.625 mg/mL, 0.156 mg/mL, and 0.156 mg/mL, respectively. The experimental results demonstrated that these three drugs could inhibit the growth of S. aureus and the formation of biofilm by altering the permeability of cell membrane and interfering with bacterial metabolic activities. The scavenging effects on DPPH radical and hydroxyl radical indicated that the antioxidant effect of the three drugs was EOCM > carvacrol > thymol.
Article
Plant Sciences
Jiraporn Laoung-on, Churdsak Jaikang, Kanokporn Saenphet, Paiwan Sudwan
Summary: The study found that the aqueous extract of white lotus petals has higher antioxidant activity and promotes sperm viability, reducing oxidative stress and improving sperm vitality.
Article
Biochemistry & Molecular Biology
Fatima Zahra Kamal, Radu Lefter, Cosmin-Teodor Mihai, Hanane Farah, Alin Ciobica, Ahmad Ali, Iulian Radu, Ioannis Mavroudis, Abdellah Ech-Chahad
Summary: Taraxacum officinale (TO) essential oil has significant antioxidant and antiproliferative effects. In vivo, it can protect the liver and kidneys from oxidative stress. In vitro, it exhibits low scavenging activity against free radicals and moderate reducing power. It also inhibits the growth of HeLa cells.
Article
Engineering, Chemical
Sara Rached, Hamada Imatara, Amar Habsaoui, Khaoula Mzioud, Sara Haida, Asmaa Saleh, Omkulthom Al Kamaly, Ahmad Alahdab, Mohammad Khalid Parvez, Samah Ourras, Souad El Fartah
Summary: As consumer trends shift towards more natural and ecological consumption patterns, industrialists are actively working towards substituting synthetic chemicals with natural and vegan products that contain bioactive properties. By focusing on the Marrubium vulgare L. species, this study aims to contribute to the valorization of aromatic and medicinal Moroccan plants by characterizing its chemical composition and biological activities, such as antioxidant and antifungal properties.
Article
Food Science & Technology
Yi-Ping Yu, Shu-Jung Lai, Chien-Ru Chang, Wen-Chi Chen, Shih-Hsiung Wu, Chun-Ping Lu
Summary: This study prepared lotus seed protein hydrolysate (LSPH) using Flavourzyme and evaluated its antioxidant activities. The results showed that the low molecular weight fragments generated from Flavourzyme hydrolysis of lotus seed protein have potential as nutraceutical or health promoting supplements due to their antioxidant activities.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Ashok Kumar Mandal, Samrat Paudel, Anisha Pandey, Parasmani Yadav, Prateek Pathak, Maria Grishina, Mariusz Jaremko, Abdul-Hamid Emwas, Habibullah Khalilullah, Amita Verma
Summary: The study investigated the antioxidant and anticancer activities of Psidium guajava L. essential oil, demonstrating its potential therapeutic value against breast cancer. The bioactive compounds in the oil showed promising properties in inhibiting tumor growth and exhibited drug likeness properties according to ADME analysis, suggesting their potential for novel drug discovery.
Article
Horticulture
Zoran S. S. Ilic, Zarko Kevresan, Ljubomir Sunic, Ljiljana Stanojevic, Lidija Milenkovic, Jelena Stanojevic, Aleksandra Milenkovic, Dragan Cvetkovic
Summary: Chemical composition of sage essential oils (SEOs) from wild and cultivated plants, with shading or not, was investigated. The yield of SEOs from wild plants (3.51 mL/100 g) was higher than that from cultivated plants (shaded plants: 3.20 mL/100 g and non-shaded plants: 2.56 mL/100 g). The main components of SEO from wild plants were cis-thujone, camphor, 1,8-cineole, veridiflorol, and borneol. Net shading decreased the content of toxic cis-thujone in sage and cultivated sage showed stronger antioxidant activity compared to wild sage plants.
Article
Agricultural Engineering
Seyed Ali Moetamedipoor, Mohammad Jamal Saharkhiz, Ahmad Reza Khosravi, Abolfazl Jowkar
Summary: Mentha, an important aromatic plant in the Lamiaceae family, was studied for its essential oil yield and components in different regions of Iran. Gas chromatography analysis revealed the diverse composition of its essential oils, with each species consisting of 46-64 constituents. The study identified new constituents and highlighted the importance of understanding the genetic and proteomic levels of these mint species.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Integrative & Complementary Medicine
Nausheen Nazir, Muhammad Zahoor, Faheem Uddin, Mohammad Nisar
Summary: The essential oil extracted from the fruits of Elaeagnus umbellata demonstrated reasonable antioxidant, anticholinesterase, and antidiabetic potentials, suggesting it could be a potential alternative medicine in treating diabetes and neurodegenerative disorders. However, further studies are needed to isolate responsible compounds and evaluate the observed potential in animal models.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2021)
Article
Agricultural Engineering
Hamid Ahadi, Majid Shokrpour, Reza Fatahi, Mohammad Reza Naghavi, Mohammad Hossein Mirjalili
Summary: The metabolic diversity of 24 Iranian Rosa damascena genotypes was studied, and major compounds and phytochemical markers were identified. This study provides valuable information for further commercial cultivation and production of essential oils, flavonoids, and anthocyanins.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Pharmacology & Pharmacy
Wenhao Nan, Li Ding, Houjie Chen, Fahim U. Khan, Lu Yu, Xinbing Sui, Xiaojun Shi
FRONTIERS IN PHARMACOLOGY
(2018)
Article
Neurosciences
Li Ding, Wen-Hao Nan, Xian-Bing Zhu, Xiao-Ming Li, Li-Yan Zhou, Hou-Jie Chen, Lu Yu, Fahim Ullah Khan, Han-Bing Zhong, Xiao-Jun Shi
CNS NEUROSCIENCE & THERAPEUTICS
(2019)
Article
Pharmacology & Pharmacy
Fahim Ullah Khan, Nana Yaa Gyaama Owusu-Tieku, Xiaoyong Dai, Kewei Liu, Yanping Wu, Hsiang-I Tsai, Hongbo Chen, Chunhui Sun, Laiqiang Huang
FRONTIERS IN PHARMACOLOGY
(2019)
Article
Chemistry, Multidisciplinary
Hsiang- Tsai, Yingyi Wu, Xiaoyan Liu, Zhanxue Xu, Longshan Liu, Changxi Wang, Huanxi Zhang, Yisheng Huang, Linglu Wang, Weixian Zhang, Dandan Su, Fahim Ullah Khan, Xiaofeng Zhu, Rongya Yang, Yuxin Pang, John E. Eriksson, Haitao Zhu, Dongqing Wang, Bo Jia, Fang Cheng, Hongbo Chen
Summary: A study demonstrates that the bioengineering strategy of concurrently displaying FGL1/PD-L1 on the surface of small extracellular vesicles (sEVs) can inhibit T cell activation and proliferation, reduce transplant rejection, and prolong graft survival.
Article
Biochemistry & Molecular Biology
Fariha Kanwal, Mingming Ma, Muhammad Fayyaz ur Rehman, Fahim-ullah Khan, Shai E. Elizur, Aima Iram Batool, Chi Chiu Wang, Tahira Tabassum, Changrui Lu, Yao Wang
Summary: By utilizing a nanoparticle-based drug delivery system, aspirin can be effectively delivered to breast cancer cells for targeted therapy. Compared to free aspirin, the drug delivery system demonstrates higher cytotoxicity and anti-proliferative effects.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2022)
Article
Public, Environmental & Occupational Health
Muneeba Wali, Mir Sadiq Shah, Tayyab Ur Rehman, Hammad Wali, Masroor Hussain, Laiq Zaman, Fahim Ullah Khan, Autif Hussain Mangi
Summary: The present study aimed to detect the presence of the cfr gene in clinical MRSA isolates. The results showed that multi-drug resistance among resistant MRSA isolates is largely attributed to the presence of the cfr gene, and the horizontal dissemination of the cfr gene among MRSA strains is facilitated by cfr-carrying transposons and plasmids.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2022)
