Antibiotic research in the age of omics: from expression profiles to interspecies communication

targetTB: A target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis

(2012) Karthik Raman et al.   BMC Systems Biology

Further Characterization ofBacillus subtilisAntibiotic Biosensors and Their Use for Antibacterial Mode-of-Action Studies

(2011) Katherine R. Mariner et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Proteomic Signature of Fatty Acid Biosynthesis Inhibition Available for In Vivo Mechanism-of-Action Studies

(2011) Michaela Wenzel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel classes of antibiotics or more of the same?

(2011) Anthony RM Coates et al.   BRITISH JOURNAL OF PHARMACOLOGY

Discovery research: the scientific challenge of finding new antibiotics

(2011) D. M. Livermore et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Proteome Analyses of Cellular Proteins in Methicillin-Resistant Staphylococcus aureus Treated with Rhodomyrtone, a Novel Antibiotic Candidate

(2011) Wipawadee Sianglum et al.   PLoS One

Proteomic signatures in antibiotic research

(2011) Michaela Wenzel et al.   PROTEOMICS

Tobramycin at subinhibitory concentration inhibits the RhlI/R quorum sensing system in a Pseudomonas aeruginosaenvironmental isolate

(2010) Fedora Babić et al.   BMC INFECTIOUS DISEASES

Revealing fosfomycin primary effect on Staphylococcus aureus transcriptome: modulation of cell envelope biosynthesis and phosphoenolpyruvate induced starvation

(2010) Marko Petek et al.   BMC MICROBIOLOGY

Three Decades of  -Lactamase Inhibitors

(2010) S. M. Drawz et al.   CLINICAL MICROBIOLOGY REVIEWS

Effects of the antimicrobial peptide gomesin on the global gene expression profile, virulence and biofilm formation ofXylella fastidiosa

(2010) Andréa C. Fogaça et al.   FEMS MICROBIOLOGY LETTERS

σB-dependent protein induction in Listeria monocytogenes during vancomycin stress

(2010) Ji-Hyun Shin et al.   FEMS MICROBIOLOGY LETTERS

Assessment of transcriptional responses of Bacillus subtilis cells to the antibiotic enduracidin, which interferes with cell wall synthesis, using a high-density tiling chip

(2010) Andriansjah Rukmana et al.   GENES & GENETIC SYSTEMS

Proteomic Analysis of theEnterococcus faecalisV583 Strain and Clinical Isolate V309 under Vancomycin Treatment

(2010) Xuesong Wang et al.   JOURNAL OF PROTEOME RESEARCH

A Novel Negative Regulation Mechanism of Bacterial Outer Membrane Proteins in Response to Antibiotic Resistance

(2010) Xiang-Min Lin et al.   JOURNAL OF PROTEOME RESEARCH

Quantitative Proteomic Analysis of Cell Wall and Plasma Membrane Fractions from Multidrug-ResistantAcinetobacter baumannii

(2010) Sung-Ho Yun et al.   JOURNAL OF PROTEOME RESEARCH

Immense Essence of Excellence: Marine Microbial Bioactive Compounds

(2010) Ira Bhatnagar et al.   Marine Drugs

Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms

(2010) Marnix H. Medema et al.   NATURE REVIEWS MICROBIOLOGY

Proteomic analysis of streptomycin resistant and sensitive clinical isolates of Mycobacterium tuberculosis

(2010) Prashant Sharma et al.   Proteome Science

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

(2010) Kevin Pethe et al.   Nature Communications

The Lipopeptide Antibiotic Friulimicin B Inhibits Cell Wall Biosynthesis through Complex Formation with Bactoprenol Phosphate

(2009) T. Schneider et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Transcriptional Signature following Inhibition of Early-Stage Cell Wall Biosynthesis in Staphylococcus aureus

(2009) A. J. O'Neill et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Daptomycin versus Friulimicin B: In-Depth Profiling of Bacillus subtilis Cell Envelope Stress Responses

(2009) T. Wecke et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vivo and In Vitro Patterns of the Activity of Simocyclinone D8, an Angucyclinone Antibiotic from Streptomyces antibioticus

(2009) L. M. Oppegard et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Generic and Specific Adaptive Responses of Streptococcus pneumoniae to Challenge with Three Distinct Antimicrobial Peptides, Bacitracin, LL-37, and Nisin

(2009) J. A. Majchrzykiewicz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Influence of Tigecycline on Expression of Virulence Factors in Biofilm-Associated Cells of Methicillin-Resistant Staphylococcus aureus

(2009) K. Smith et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genetic Analysis of Factors Affecting Susceptibility of Bacillus subtilis to Daptomycin

(2009) A.-B. Hachmann et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Engineering of Bacillus subtilis 168 for Increased Nisin Resistance

(2009) M. E. Hansen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Automated genome mining for natural products

(2009) Michael HT Li et al.   BMC BIOINFORMATICS

Transcriptome analysis of the responses of Staphylococcus aureus to antimicrobial peptides and characterization of the roles of vraDE and vraSR in antimicrobial resistance

(2009) Milla Pietiäinen et al.   BMC GENOMICS

Exploring and dissecting genome-wide gene expression responses of Penicillium chrysogenum to phenylacetic acid consumption and penicillinG production

(2009) Diana M Harris et al.   BMC GENOMICS

Response of Bacillus cereus ATCC 14579 to challenges with sublethal concentrations of enterocin AS-48

(2009) María J Grande Burgos et al.   BMC MICROBIOLOGY

Esculentin-1b(1-18) - a membrane-active antimicrobial peptide that synergizes with antibiotics and modifies the expression level of a limited number of proteins in Escherichia coli

(2009) Ludovica Marcellini et al.   FEBS Journal

Transcriptional profile of theShigella flexneriresponse to an alkaloid: berberine

(2009) Hua Fu et al.   FEMS MICROBIOLOGY LETTERS

Response of Staphylococcus aureus to subinhibitory concentrations of a sequence-selective, DNA minor groove cross-linking pyrrolobenzodiazepine dimer

(2009) M. Doyle et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Comparative Genome-Scale Metabolic Reconstruction and Flux Balance Analysis of Multiple Staphylococcus aureus Genomes Identify Novel Antimicrobial Drug Targets

(2009) D.-S. Lee et al.   JOURNAL OF BACTERIOLOGY

Identification of a Polymyxin Synthetase Gene Cluster of Paenibacillus polymyxa and Heterologous Expression of the Gene in Bacillus subtilis

(2009) S.-K. Choi et al.   JOURNAL OF BACTERIOLOGY

CLUSEAN: A computer-based framework for the automated analysis of bacterial secondary metabolite biosynthetic gene clusters

(2009) T. Weber et al.   JOURNAL OF BIOTECHNOLOGY

Subinhibitory concentrations of the cationic antimicrobial peptide colistin induce the pseudomonas quinolone signal in Pseudomonas aeruginosa

(2009) J. Cummins et al.   MICROBIOLOGY-SGM

Global transcriptional response to vancomycin in Mycobacterium tuberculosis

(2009) R. Provvedi et al.   MICROBIOLOGY-SGM

Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12

(2009) Takeshi Hosaka et al.   NATURE BIOTECHNOLOGY

A low concentration of azithromycin inhibits the mRNA expression of N-acyl homoserine lactone synthesis enzymes, upstream of lasI or rhlI, in Pseudomonas aeruginosa

(2009) Toshihiro Kai et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Proteomic and Transcriptomic Analysis of Aspergillus fumigatus on Exposure to Amphotericin B

(2008) P. Gautam et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effects of Antibiotics on Quorum Sensing in Pseudomonas aeruginosa

(2008) M. E. Skindersoe et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Brominated Furanones Inhibit Biofilm Formation by Salmonella enterica Serovar Typhimurium

(2008) J. C. A. Janssens et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Insights into the Mode of Action of Chitosan as an Antibacterial Compound

(2008) D. Raafat et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Microarray analysis of toxicogenomic effects of triclosan on Staphylococcus aureus

(2008) Hyeung-Jin Jang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The lantibiotic mersacidin is a strong inducer of the cell wall stress response of Staphylococcus aureus

(2008) Peter Sass et al.   BMC MICROBIOLOGY

Known Bioactive Small Molecules Probe the Function of a Widely Conserved but Enigmatic Bacterial ATPase, YjeE

(2008) Chand Singh Mangat et al.   CHEMISTRY & BIOLOGY

Renaissance in antibacterial discovery from actinomycetes

(2008) R BALTZ   CURRENT OPINION IN PHARMACOLOGY

Global transcriptional profiles ofStaphylococcus aureustreated with berberine chloride

(2008) Dacheng Wang et al.   FEMS MICROBIOLOGY LETTERS

Mode of action of human β-defensin 3 against Staphylococcus aureus and transcriptional analysis of responses to defensin challenge

(2008) Vera Sass et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The fusidic acid stimulon of Staphylococcus aureus

(2008) Alejandro Delgado et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Mycobacterium tuberculosis DNA repair in response to subinhibitory concentrations of ciprofloxacin

(2008) D. M. O'Sullivan et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Proteomic analysis of triclosan resistance in Salmonella enterica serovar Typhimurium

(2008) M. A. Webber et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The Rcs Phosphorelay Is a Cell Envelope Stress Response Activated by Peptidoglycan Stress and Contributes to Intrinsic Antibiotic Resistance

(2008) M. E. Laubacher et al.   JOURNAL OF BACTERIOLOGY

Microarray analysis of the transcriptional responses of Clostridium difficile to environmental and antibiotic stress

(2008) J. E. Emerson et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Proteomic analysis of outer membrane proteins from Acinetobacter baumannii DU202 in tetracycline stress condition

(2008) Sung-Ho Yun et al.   JOURNAL OF MICROBIOLOGY

The Proteomic Response ofMycobacterium smegmatisto Anti-Tuberculosis Drugs Suggests Targeted Pathways

(2008) Rong Wang et al.   JOURNAL OF PROTEOME RESEARCH

ClustScan : an integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures

(2008) Antonio Starcevic et al.   NUCLEIC ACIDS RESEARCH

2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining

(2008) C. Corre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA