Blockage of the early step of lankacidin biosynthesis caused a large production of pentamycin, citreodiol and epi-citreodiol in Streptomyces rochei

Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters

(2013) Haruo Ikeda et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Engineered Streptomyces avermitilis Host for Heterologous Expression of Biosynthetic Gene Cluster for Secondary Metabolites

(2013) Mamoru Komatsu et al.   ACS Synthetic Biology

The Butenolide Signaling Molecules SRB1 and SRB2 Induce Lankacidin and Lankamycin Production in Streptomyces rochei

(2012) Kenji Arakawa et al.   CHEMBIOCHEM

pSLA2-M ofStreptomyces rocheiIs a Composite Linear Plasmid Characterized by Self-Defense Genes and Homology with pSLA2-L

(2011) Yingjie YANG et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

An Additional Dehydratase-Like Activity is Required for Lankacidin Antibiotic Biosynthesis

(2011) Jeroen S. Dickschat  et al.   CHEMBIOCHEM

Enzymatic diastereo- and enantioselective synthesis of α-alkyl-α,β-dihydroxyketones

(2011) Pier Paolo Giovannini et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit

(2011) M. J. Belousoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Lankamycin Biosynthesis inStreptomyces rocheiby Two SARP Genes,srrYandsrrZ

(2010) Toshihiro SUZUKI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Regio- and Stereospecificity of Filipin Hydroxylation Sites Revealed by Crystal Structures of Cytochrome P450 105P1 and 105D6 fromStreptomyces avermitilis

(2010) Lian-Hua Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics

(2010) T. Auerbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extensive Mutational Analysis of Modular-Iterative Mixed Polyketide Biosynthesis of Lankacidin inStreptomyces rochei

(2009) Satoshi TATSUNO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Genomic basis for natural product biosynthetic diversity in the actinomycetes

(2009) Markus Nett et al.   NATURAL PRODUCT REPORTS

Silyl-Substituted Spirodiepoxides: Stereoselective Formation and Regioselective Opening

(2009) Partha Ghosh et al.   ORGANIC LETTERS

Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering

(2008) Carlos Olano et al.   METABOLIC ENGINEERING

Extracellular signalling, translational control, two repressors and an activator all contribute to the regulation of methylenomycin production inStreptomyces coelicolor

(2008) Sean O'Rourke et al.   MOLECULAR MICROBIOLOGY