Postsynaptic Proteome of Non-Demented Individuals with Alzheimer’s Disease Neuropathology

Redox Proteomics Analysis of Brains from Subjects with Amnestic Mild Cognitive Impairment Compared to Brains from Subjects with Preclinical Alzheimer's Disease: Insights into Memory Loss in MCI

(2018) Christopher D. Aluise et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuronal Hemoglobin is Reduced in Alzheimer's Disease, Argyrophilic Grain Disease, Parkinson's Disease, and Dementia with Lewy Bodies

(2018) Isidro Ferrer et al.   JOURNAL OF ALZHEIMERS DISEASE

Identification of SPARC-like 1 Protein as Part of a Biomarker Panel for Alzheimer's Disease in Cerebrospinal Fluid

(2018) Baharak Vafadar-Isfahani et al.   JOURNAL OF ALZHEIMERS DISEASE

Pyruvate Carboxylase and Pentose Phosphate Fluxes are Reduced in AβPP-PS1 Mouse Model of Alzheimer's Disease: A 13C NMR Study

(2018) Vivek Tiwari et al.   JOURNAL OF ALZHEIMERS DISEASE

Synaptic Change in the Posterior Cingulate Gyrus in the Progression of Alzheimer's Disease

(2018) Stephen W. Scheff et al.   JOURNAL OF ALZHEIMERS DISEASE

Presenilin-1 mutations and Alzheimer’s disease

(2017) Raymond J. Kelleher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease

(2017) Harm J. van de Haar et al.   RADIOLOGY

Aging and Caloric Restriction Research: A Biological Perspective With Translational Potential

(2017) Priya Balasubramanian et al.   EBioMedicine

The Alzheimer's Disease Mitochondrial Cascade Hypothesis

(2017) Russell H. Swerdlow et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidatively Modified Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) and Alzheimer's Disease: Many Pathways to Neurodegeneration

(2017) D. Allan Butterfield et al.   JOURNAL OF ALZHEIMERS DISEASE

Near infrared light decreases synaptic vulnerability to amyloid beta oligomers

(2017) Michele M. Comerota et al.   Scientific Reports

Blood–brain barrier and blood–cerebrospinal fluid barrier in normal and pathological conditions

(2016) Masaki Ueno et al.   Brain Tumor Pathology

Non-Demented Individuals with Alzheimer's Disease Neuropathology: Resistance to Cognitive Decline May Reveal New Treatment Strategies

(2016) Olga Zolochevska et al.   CURRENT PHARMACEUTICAL DESIGN

Actin dynamics and cofilin-actin rods in alzheimer disease

(2016) James R. Bamburg et al.   Cytoskeleton

Caloric restriction and the precision-control of autophagy: A strategy for delaying neurodegenerative disease progression

(2016) C. Ntsapi et al.   EXPERIMENTAL GERONTOLOGY

A method to determine insulin responsiveness in synaptosomes isolated from frozen brain tissue

(2016) Whitney Franklin et al.   JOURNAL OF NEUROSCIENCE METHODS

Changes in the Chemical Barrier Composition of Tears in Alzheimer’s Disease Reveal Potential Tear Diagnostic Biomarkers

(2016) Gergő Kalló et al.   PLoS One

Rationalising the role of Keratin 9 as a biomarker for Alzheimer’s disease

(2016) Joanna L. Richens et al.   Scientific Reports

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory

(2016) M. Fá et al.   Scientific Reports

Preserved neurogenesis in non-demented individuals with AD neuropathology

(2016) David Briley et al.   Scientific Reports

The genetic landscape of Alzheimer disease: clinical implications and perspectives

(2015) Caroline Van Cauwenberghe et al.   GENETICS IN MEDICINE

Inhibition of clathrin-mediated endocytosis prevents amyloid β-induced axonal damage

(2015) Tomoharu Kuboyama et al.   NEUROBIOLOGY OF AGING

Tau Oligomers: The Toxic Player at Synapses in Alzheimer’s Disease

(2015) Marcos J. Guerrero-Muñoz et al.   Frontiers in Cellular Neuroscience

Calcium/calmodulin-dependent kinase II and Alzheimer’s disease

(2015) Anshua Ghosh et al.   Molecular Brain

The Relationship between Amyloid Deposition, Neurodegeneration, and Cognitive Decline in Dementia

(2014) Rik Vandenberghe   Current Neurology and Neuroscience Reports

Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease

(2014) Meredith A. Chabrier et al.   NEUROBIOLOGY OF DISEASE

Normalized Mini-Mental State Examination for Assessing Cognitive Change in Population-Based Brain Aging Studies

(2014) Viviane Philipps et al.   NEUROEPIDEMIOLOGY

Mitochondrial Dysfunction: Different Routes to Alzheimer’s Disease Therapy

(2014) Pasquale Picone et al.   Oxidative Medicine and Cellular Longevity

Dynamin 1 Is Required for Memory Formation

(2014) Mauro Fà et al.   PLoS One

Repair of Oxidative DNA Damage, Cell-Cycle Regulation and Neuronal Death May Influence the Clinical Manifestation of Alzheimer’s Disease

(2014) Aderbal R. T. Silva et al.   PLoS One

Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels

(2014) Mariet Allen et al.   Alzheimers Research & Therapy

Regulation of pyruvate metabolism and human disease

(2013) Lawrence R. Gray et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Vinculin–actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth

(2013) Ingo Thievessen et al.   JOURNAL OF CELL BIOLOGY

Peroxiredoxin 5 links mitochondrial redox signalling with calcium dynamics: impact on Parkinson's disease

(2013) Gavin P. Davey et al.   JOURNAL OF NEUROCHEMISTRY

A mitochondrial location for haemoglobins—Dynamic distribution in ageing and Parkinson's disease

(2013) Freya Shephard et al.   MITOCHONDRION

Generation of Amyloid-β Is Reduced by the Interaction of Calreticulin with Amyloid Precursor Protein, Presenilin and Nicastrin

(2013) Nina Stemmer et al.   PLoS One

Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies

(2013) Zhichun Chen et al.   PROGRESS IN NEUROBIOLOGY

Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

(2012) Cristian A. Lasagna-Reeves et al.   FASEB JOURNAL

Neurofilaments at a glance

(2012) A. Yuan et al.   JOURNAL OF CELL SCIENCE

Proteomic analysis of the cerebrospinal fluid in multiple sclerosis and neuromyelitis optica patients

(2012) SHOUFENG JIANG et al.   Molecular Medicine Reports

Absence of amyloid β oligomers at the postsynapse and regulated synaptic Zn2+ in cognitively intact aged individuals with Alzheimer’s disease neuropathology

(2012) Nicole L Bjorklund et al.   Molecular Neurodegeneration

Septins: the fourth component of the cytoskeleton

(2012) Serge Mostowy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Interactions between Amyloid-β and Hemoglobin: Implications for Amyloid Plaque Formation in Alzheimer's Disease

(2012) Jia-Ying Chuang et al.   PLoS One

Dynamin 1 Regulates Amyloid Generation through Modulation of BACE-1

(2012) Li Zhu et al.   PLoS One

Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease

(2012) Laura E. Donovan et al.   Proteomics Clinical Applications

Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

Quantification of Cysteinyl S-Nitrosylation by Fluorescence in Unbiased Proteomic Studies

(2011) John E. Wiktorowicz et al.   BIOCHEMISTRY

A Role for Calcineurin in Alzheimers Disease

(2011) Lindsay C. Reese et al.   Current Neuropharmacology

The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner

(2011) Anne Gauthier-Kemper et al.   JOURNAL OF CELL BIOLOGY

Dysregulated phosphorylation of Ca2+/calmodulin-dependent protein kinase II-α in the hippocampus of subjects with mild cognitive impairment and Alzheimer’s disease

(2011) Lindsay C. Reese et al.   JOURNAL OF NEUROCHEMISTRY

Up-regulation of the mitochondrial malate dehydrogenase by oxidative stress is mediated by miR-743a

(2011) Qingli Shi et al.   JOURNAL OF NEUROCHEMISTRY

Selective, quantitative measurement of releasable synaptic zinc in human autopsy hippocampal brain tissue from Alzheimer's disease patients

(2011) Nicole L. Bjorklund et al.   JOURNAL OF NEUROSCIENCE METHODS

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions

(2011) Carsten Janke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Alzheimer's Disease and Non-Demented High Pathology Control Nonagenarians: Comparing and Contrasting the Biochemistry of Cognitively Successful Aging

(2011) Chera L. Maarouf et al.   PLoS One

De Novo Protein Synthesis of Syntaxin-1 and Dynamin-1 in Long-Term Memory Formation Requires CREB1 Gene Transcription in Lymnaea stagnalis

(2010) Cong-Hui Guo et al.   BEHAVIOR GENETICS

Signaling Role of Cdc42 in Regulating Mammalian Physiology

(2010) Jaime Melendez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Actin in dendritic spines: connecting dynamics to function

(2010) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1

(2010) Etienne Boulter et al.   NATURE CELL BIOLOGY

Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study

(2010) Patricia L. Kramer et al.   NEUROBIOLOGY OF AGING

Asymmetric Clathrin-Mediated Endocytosis Drives Repulsive Growth Cone Guidance

(2010) Takuro Tojima et al.   NEURON

Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition

(2009) Giulio Taglialatela et al.   BEHAVIOURAL BRAIN RESEARCH

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

(2009) Paula I. Moreira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

β-Amyloid Impairs AMPA Receptor Trafficking and Function by Reducing Ca2+/Calmodulin-dependent Protein Kinase II Synaptic Distribution

(2009) Zhenglin Gu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurons express hemoglobin α- and β-chains in rat and human brains

(2009) Franziska Richter et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

(2009) H. M. Abdul et al.   JOURNAL OF NEUROSCIENCE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease

(2009) Joseph L. Price et al.   NEUROBIOLOGY OF AGING

Factors associated with resistance to dementia despite high Alzheimer disease pathology

(2009) D. Erten-Lyons et al.   NEUROLOGY

Oligomeric amyloid   associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

(2009) R. M. Koffie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toward the proteome of the human peripheral blood eosinophil

(2009) Christof Straub et al.   Proteomics Clinical Applications

Selective induction of calcineurin activity and signaling by oligomeric amyloid beta

(2008) Lindsay C. Reese et al.   AGING CELL

Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly

(2008) Howard Jay Aizenstein et al.   ARCHIVES OF NEUROLOGY

Novel functions of the α-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease

(2008) Qingli Shi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Creatine kinase B deficient neurons exhibit an increased fraction of motile mitochondria

(2008) Jan WP Kuiper et al.   BMC NEUROSCIENCE

A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain

(2008) Jae K. Ryu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Expression of Hemoglobin in Rodent Neurons

(2008) Dominik W Schelshorn et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuronal Hypertrophy in Asymptomatic Alzheimer Disease

(2008) Diego Iacono et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology

(2008) Winnie S. Liang et al.   NEUROBIOLOGY OF AGING

Interaction of Calreticulin with Amyloid Beta Peptide 1-42

(2008) G. Houen et al.   PROTEIN AND PEPTIDE LETTERS

Saturation fluorescence labeling of proteins for proteomic analyses

(2007) Elizabeth Pretzer et al.   ANALYTICAL BIOCHEMISTRY