Article
Allergy
Hsin-Ju Lee, Hui-Ju Tsai, Hsin-Yi Huang, Chun-Chun Gau, Chia-Hua Ho, Jing-Long Huang, Tsung-Chieh Yao
Summary: This study found a positive correlation between cord blood IgE levels and allergic sensitization, FeNO elevation, and asthma in Asian schoolchildren. Cord blood IgE could be a useful indicator for identifying newborns at risk for subsequent allergic sensitization and allergic airway inflammation.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Article
Allergy
Magnus Lindqvist, Katja Biering Leth-Moller, Allan Linneberg, Inger Kull, Anna Bergstrom, Antonios Georgellis, Magnus P. Borres, Agneta Ekebom, Marianne van Hage, Erik Melen, Marit Westman
Summary: Patients with pollen-induced allergic rhinitis face a high risk of persistent disease for at least 20 years, with childhood to adolescence being the most critical period for disease progression. The study findings underscore the close relationship between sensitization, allergic rhinitis, and asthma.
Article
Environmental Sciences
Jaehyun Park, Jeeyoung Kim, Esther Kim, Woo Jin Kim, Sungho Won
Summary: Prenatal lead exposure was found to be associated with altered, gender-specific patterns of DNA methylation in Korean infants. In males, maternal blood lead level during early pregnancy was linked to 18 CpG sites, while a CpG site near the NBAS gene was associated during late pregnancy. No significant association was observed in females.
ENVIRONMENTAL RESEARCH
(2021)
Article
Allergy
Danielle R. Stevens, Neil Perkins, Zhen Chen, Rajesh Kumar, William Grobman, Akila Subramaniam, Joseph Biggio, Katherine L. Grantz, Seth Sherman, Matthew Rohn, Pauline Mendola
Summary: This study aimed to identify and characterize trajectories of gestational asthma control in a US-based prospective pregnancy cohort. Two trajectories were identified: one with worsened asthma control and one with stable asthma control.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2022)
Article
Nutrition & Dietetics
Oraporn Dumrongwongsiri, Pattanee Winichagoon, Nalinee Chongviriyaphan, Umaporn Suthutvoravut, Veit Grote, Berthold Koletzko
Summary: Maternal nutritional status and mode of delivery are significantly associated with zinc and iron stores at birth, highlighting the importance of ensuring adequate nutrition during preconception and pregnancy to build sufficient nutrient stores for infants.
Article
Medicine, General & Internal
Muna Saleh, Michele Compagno, Sofia Pihl, Helena Strevens, Barbro Persson, Jonas Wettero, Bo Nilsson, Christopher Sjowall
Summary: The complement system plays a crucial role during pregnancy, but excessive activation can lead to pregnancy complications. The clinical value of complement system activation during pregnancy is still unclear. This study analyzed complement proteins in maternal plasma and umbilical cord blood, and found that the reference values were applicable to the majority of samples.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Allergy
Loreen Thuermann, Matthias Kloes, Sebastian D. Mackowiak, Matthias Bieg, Tobias Bauer, Naveed Ishaque, Marey Messingschlager, Carl Herrmann, Stefan Roeder, Mario Bauer, Sascha Schaeuble, Erik Faessler, Udo Hahn, Dieter Weichenhan, Oliver Muecke, Christoph Plass, Michael Borte, Erika von Mutius, Gabriele I. Stangl, Roger Lauener, Anne M. Karvonen, Amandine Divaret-Chauveau, Josef Riedler, Joachim Heinrich, Marie Standl, Andrea von Berg, Beate Schaaf, Gunda Herberth, Michael Kabesch, Roland Eils, Saskia Trump, Irina Lehmann
Summary: This study used whole genome bisulfite sequencing to identify dysregulation of enhancer regions as a hallmark of childhood asthma. Abnormal DNA methylation was found in key immune genes and was linked to prenatal influences and genetic susceptibility.
Article
Allergy
Eric M. Wohlford, Peter F. Huang, Jennifer R. Elhawary, Lauren A. Millette, Maria G. Contreras, Jonathan Witonsky, Cecile T. J. Holweg, Sam S. Oh, Christine Lee, Christine Merenda, Ronald L. Rabin, Richardae Araojo, Angel C. Y. Mak, Celeste S. Eng, Donglei Hu, Scott Huntsman, Michael A. LeNoir, Jose R. Rodriguez-Santana, Luisa N. Borrell, Esteban G. Burchard
Summary: Population-specific associations between blood parameters and asthma subtypes with asthma outcomes were found, suggesting eligibility for asthma biologic therapies differs across pediatric racial/ethnic populations. More studies in diverse populations are needed for equitable treatment of minority patients with asthma.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2021)
Article
Geriatrics & Gerontology
Nicolina Wiklund, Mikael Ludvigsson, Katarina Nagga, Johanna Simmons
Summary: This study examined elder abuse and victimization earlier in life among hospitalized older patients in Sweden. The prevalence of elder abuse was found to be significant, with a high percentage of victims also reporting previous victimization. The study highlights the importance of a life-course perspective in both research and clinical practice on elder abuse.
Article
Nutrition & Dietetics
Meera Shanmuganathan, Meghan Bogert, Zachary Kroezen, Philip Britz-McKibbin, Stephanie A. Atkinson
Summary: This study explores the intake of choline and carnitine during pregnancy and their effects on choline and carnitine metabolites. The findings showed that despite inadequate choline intake, serum-free choline levels were elevated in late pregnancy and enriched in cord blood compared with maternal serum. However, serum carnitine levels declined in late pregnancy. The higher cord:maternal concentrations in choline and carnitine metabolites suggest active uptake in late pregnancy, reflecting the importance of these circulating metabolites in fetal development.
JOURNAL OF NUTRITION
(2023)
Article
Rheumatology
Nafise Ghalandari, Erik Kemper, Ineke (Hubertina) Crijns, Gertjan Wolbink, Theo Rispens, Hieronymus T. W. Smeele, Radboud J. E. M. Dolhain
Summary: Compliance with the EULAR-PtC guidelines results in absence or low levels of TNFi in cord blood, as demonstrated by the analysis of TNFi concentrations in maternal and cord blood samples from 111 patients enrolled in the study.
ANNALS OF THE RHEUMATIC DISEASES
(2022)
Article
Allergy
Rikke Bjersand Sunde, Jonathan Thorsen, Frederikke Skov, Laura Hesselberg, Julie Kyvsgaard, Nilofar V. Folsgaard, Ann-Marie Malby Schoos, Jakob Stokholm, Klaus Bonnelykke, Bo Chawes
Summary: Fraction of exhaled nitric oxide is elevated in children with asthma and is correlated with asthma-associated traits depending on the presence of aeroallergen sensitization.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2023)
Article
Environmental Sciences
Hesam Movassagh, Yuliya Halchenko, Vanitha Sampath, Unni C. Nygaard, Brian Jackson, David Robbins, Zhigang Li, Kari C. Nadeau, Margaret R. Karagas
Summary: The study found that gestational exposure to mercury concentrations may alter the frequency of cord blood T cells and placental gene expression, potentially leading to immunotoxic effects.
ENVIRONMENTAL RESEARCH
(2021)
Article
Nutrition & Dietetics
Michael Ceulemans, Joline van de Vel, Dorine W. W. Swinkels, Coby M. M. Laarakkers, Jaak Billen, Kristel Van Calsteren, Karel Allegaert
Summary: This observational study aimed to provide the first data on cord blood hepcidin levels in a Belgian cohort and determine variables associated with cord blood hepcidin concentrations. The study found a moderate correlation between cord blood hepcidin and cord blood ferritin and hemoglobin, as well as an association with mode of delivery.
Article
Engineering, Environmental
Aolin Wang, Dimitri Panagopoulos Abrahamsson, Ting Jiang, Miaomiao Wang, Rachel Morello-Frosch, June-Soo Park, Marina Sirota, Tracey J. Woodruff
Summary: A proof-of-concept study was conducted to identify and prioritize potentially ubiquitous chemical exposures during a critical period of development by analyzing matched maternal/cord blood samples. Liquid chromatography-quadrupole time-of-flight tandem mass spectrometry was used to screen around 3500 industrial chemicals, resulting in the tentative identification of 73 suspects and confirmation of 17 chemical features. The study also identified 55 compounds not previously reported in the literature, highlighting the limited information available on their sources and uses.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Psychiatry
Nicholas Morelli, Jason Fogler, Sahil Tembulkar, Kelsey Graber, Sarah H. Lincoln, Michelle Bosquet Enlow, Joseph Gonzalez-Heydrich, Eugene J. DAngelo
EARLY INTERVENTION IN PSYCHIATRY
(2019)
Article
Environmental Sciences
Kelly J. Brunst, Marco Sanchez-Guerra, Yueh-Hsiu Mathilda Chiu, Ander Wilson, Brent A. Coull, Itai Kloog, Joel Schwartz, Kasey J. Brennan, Michelle Bosquet Enlow, Robert O. Wrightk, Andrea A. Baccarelli, Rosalind J. Wright
ENVIRONMENT INTERNATIONAL
(2018)
Article
Endocrinology & Metabolism
Michelle Bosquet Enlow, Georgios Sideridis, Yueh-Hsiu Mathilda Chiu, Farida Nentin, Elizabeth A. Howell, Blake A. Le Grand, Rosalind J. Wright
PSYCHONEUROENDOCRINOLOGY
(2019)
Article
Psychiatry
Kelsey Graber, Michelle Bosquet Enlow, Frank H. Duffy, Eugene D'Angelo, Georgios Sideridis, Damon E. Hyde, Nicholas Morelli, Sahil Tembulkar, Joseph Gonzalez-Heydrich
SCHIZOPHRENIA RESEARCH
(2019)
Article
Psychology, Developmental
Michelle Bosquet Enlow, Carter R. Petty, Cassandra Svelnys, Michaela Gusman, Michelle Huezo, Ashley Malin, Rosalind J. Wright
DEVELOPMENTAL NEUROPSYCHOLOGY
(2019)
Article
Endocrinology & Metabolism
Michelle Bosquet Enlow, Georgios Sideridis, Valentina Bollati, Mirjam Hoxha, Michele R. Hacker, Rosalind J. Wright
PSYCHONEUROENDOCRINOLOGY
(2019)
Review
Endocrinology & Metabolism
Jennifer E. Khoury, Michelle Bosquet Enlow, Andre Plamondon, Karlen Lyons-Ruth
PSYCHONEUROENDOCRINOLOGY
(2019)
Article
Behavioral Sciences
Maria Jose Rosa, Farida Nentin, Michelle Bosquet Enlow, Michele R. Hacker, Nastasia Pollas, Brent Coull, Rosalind J. Wright
STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS
(2019)
Article
Psychology, Developmental
H. Richardson, J. Taylor, F. Kane-Grade, L. Powell, M. Bosquet Enlow, C. A. Nelson
Summary: Research with three-year-old children using fNIRS showed varying functional responses in cortical regions when exposed to faces with different emotions. While STC and MPFC displayed stronger reactions to all faces compared to objects, MPFC specifically responded more to happy faces than neutral faces. There was no significant difference in preferential responses to angry or fearful faces based on emotional valence or intensity.
DEVELOPMENTAL COGNITIVE NEUROSCIENCE
(2021)
Article
Environmental Sciences
Yuri Levin-Schwartz, Whitney Cowell, Hsiao-Hsien Leon Hsu, Michelle Bosquet Enlow, Chitra Amarasiriwardena, Syam S. Andra, Rosalind J. Wright, Robert O. Wright
Summary: The study found that joint exposure to six metals in the environment may be associated with elevated anxiety symptoms during pregnancy, with cadmium, chromium, and cesium contributing the most to the mixture effect.
ENVIRONMENTAL RESEARCH
(2022)
Article
Psychology, Multidisciplinary
Cameron R. Wiley, Kennedy M. Blevins, Sheldon Cohen, Sarah D. Pressman
Summary: Research findings have indicated that positive psychological constructs are connected to better physical health. However, the role of race in this connection needs further investigation. This study explores the protective effect of positive self-evaluations against upper respiratory infection in African American and European American adults, revealing differential patterns in the health benefits between these ethnic groups.
PSYCHOLOGICAL SCIENCE
(2022)
Article
Multidisciplinary Sciences
J. David Creswell, Michael J. Tumminia, Stephen Price, Yasaman Sefidgar, Sheldon Cohen, Yiyi Ren, Jennifer Brown, Anind K. Dey, Janine M. Dutcher, Daniella Villalba, Jennifer Mankoff, Xuhai Xu, Kasey Creswell, Afsaneh Doryab, Stephen Mattingly, Aaron Striegel, David Hachen, Gonzalo Martinez, Marsha C. Lovett
Summary: Academic achievement in the first year of college is crucial for long-term success. This study investigates the role of sleep duration in predicting end-of-semester grade point average (GPA). Findings reveal that greater early-term sleep duration is associated with higher end-of-term GPA, even after controlling for previous-term GPA and daytime sleep. Every additional hour of sleep early in the semester is linked to a 0.07 increase in GPA. These results establish the importance of sleep duration in academic success during the first year of college.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Psychology, Developmental
Michelle Bosquet Enlow, Immaculata De Vivo, Carter R. Petty, Natalie Cayon, Charles A. Nelson
Summary: This study examined the relationship between temperament and telomere length in infants and children. The findings suggest that higher levels of regulation/control are associated with longer telomere length, while higher levels of surgency/extraversion are associated with slower telomere attrition.
DEVELOPMENTAL PSYCHOLOGY
(2023)
Article
Psychology, Multidisciplinary
Sheldon Cohen
Summary: Research has shown that factors such as smoking, inadequate intake of vitamin C, and chronic psychological stress increase the risk of developing respiratory illnesses after virus exposure, while social integration, social support, physical activity, adequate and efficient sleep, and moderate alcohol intake are associated with decreased risk.
PERSPECTIVES ON PSYCHOLOGICAL SCIENCE
(2021)
Review
Family Studies
Genevieve Young-Southward, Cassandra Svelnys, Ruchika Gajwani, Michelle Bosquet Enlow, Helen Minnis
CHILD MALTREATMENT
(2020)