Nanodiagnostics, nanopharmacology and nanotoxicology of platelet–vessel wall interactions

Ultrasmall superparamagnetic iron oxide nanoparticles coated with fucoidan for molecular MRI of intraluminal thrombus

(2015) Michimasa Suzuki et al.   Nanomedicine

Blood biocompatibility of surface-bound multi-walled carbon nanotubes

(2015) Alan M. Gaffney et al.   Nanomedicine-Nanotechnology Biology and Medicine

Size dependent biodistribution and toxicokinetics of iron oxide magnetic nanoparticles in mice

(2015) Lin Yang et al.   Nanoscale

Toxicity of nanoparticles embedded in paints compared to pristine nanoparticles, in vitro study

(2015) Stijn Smulders et al.   TOXICOLOGY LETTERS

Vascular Targeting of Nanocarriers: Perplexing Aspects of the Seemingly Straightforward Paradigm

(2014) Melissa Howard et al.   ACS Nano

Platelet-like Nanoparticles: Mimicking Shape, Flexibility, and Surface Biology of Platelets To Target Vascular Injuries

(2014) Aaron C. Anselmo et al.   ACS Nano

Combining Antiplatelet and Antithrombotic Therapy (Triple Therapy): What Are the Risks and Benefits?

(2014) Luis Alejandro Asencio et al.   AMERICAN JOURNAL OF MEDICINE

Co-opting biology to deliver drugs

(2014) Parisa Yousefpour et al.   BIOTECHNOLOGY AND BIOENGINEERING

Expandable Megakaryocyte Cell Lines Enable Clinically Applicable Generation of Platelets from Human Induced Pluripotent Stem Cells

(2014) Sou Nakamura et al.   Cell Stem Cell

Potentials and emerging trends in nanopharmacology

(2014) Keerti Jain et al.   CURRENT OPINION IN PHARMACOLOGY

Toxicity of TiO2 Nanoparticles to Escherichia coli: Effects of Particle Size, Crystal Phase and Water Chemistry

(2014) Xiuchun Lin et al.   PLoS One

Microvascular platforms for the study of platelet-vessel wall interactions

(2014) Ying Zheng et al.   THROMBOSIS RESEARCH

Biocompatibility of cerium dioxide and silicon dioxide nanoparticles with endothelial cells

(2014) Claudia Strobel et al.   Beilstein Journal of Nanotechnology

Hemocompatibility evaluation of different silver nanoparticle concentrations employing a modified Chandler-loop in vitro assay on human blood

(2013) Stefanie Krajewski et al.   Acta Biomaterialia

In vitro and in vivo hemostatic capabilities of a functionally integrated platelet-mimetic liposomal nanoconstruct

(2013) Christa L. Modery-Pawlowski et al.   BIOMATERIALS

Mechanisms of platelet-stimulated colon cancer invasion: role of clusterin and thrombospondin 1 in regulation of the P38MAPK-MMP-9 pathway

(2013) A. Radziwon-Balicka et al.   CARCINOGENESIS

PAMAM dendrimer derivatives as a potential drug for antithrombotic therapy

(2013) Esteban Durán-Lara et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Platelet interaction with von Willebrand factor is enhanced by shear-induced clustering of glycoprotein Ib 

(2013) E. Gitz et al.   HAEMATOLOGICA

Current immunotherapy in rheumatoid arthritis

(2013) Florian MP Meier et al.   Immunotherapy

Pegylation Increases Platelet Biocompatibility of Gold Nanoparticles

(2013) Maria Jose Santos-Martinez et al.   Journal of Biomedical Nanotechnology

Effects of the physicochemical properties of titanium dioxide nanoparticles, commonly used as sun protection agents, on microvascular endothelial cells

(2013) Claudia Strobel et al.   JOURNAL OF NANOPARTICLE RESEARCH

Nanoparticle Adhesion to the Cell Membrane and Its Effect on Nanoparticle Uptake Efficiency

(2013) Anna Lesniak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoparticles and the blood coagulation system. Part II: safety concerns

(2013) Anna N Ilinskaya et al.   Nanomedicine

Nanoparticles and the blood coagulation system. Part I: benefits of nanotechnology

(2013) Anna N Ilinskaya et al.   Nanomedicine

Progress in the characterization and safety evaluation of engineered inorganic nanomaterials in food

(2013) Haifang Wang et al.   Nanomedicine

Thermal potentiation of chemotherapy by magnetic nanoparticles

(2013) Madeline Torres-Lugo et al.   Nanomedicine

Nanodiamonds activate blood platelets and induce thromboembolism

(2013) Sharda Kumari et al.   Nanomedicine

Assessment of orally dosed commercial silver nanoparticles on humanex vivoplatelet aggregation

(2013) Kristi J. Smock et al.   Nanotoxicology

Formation of microvascular networks in vitro

(2013) John P Morgan et al.   Nature Protocols

Diesel exhaust particulate increases the size and complexity of lesions in atherosclerotic mice

(2013) Mark R Miller et al.   Particle and Fibre Toxicology

Drug Delivery Using Platelet Cancer Cell Interaction

(2013) Sounik Sarkar et al.   PHARMACEUTICAL RESEARCH

Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner

(2013) Erik Westein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multi-Ligand Poly(l-Lactic-co-Glycolic Acid) Nanoparticles Inhibit Activation of Endothelial Cells

(2013) Hao Xu et al.   Journal of Cardiovascular Translational Research

Platelet Biology and Receptor Pathways

(2013) Giovanni Cimmino et al.   Journal of Cardiovascular Translational Research

Molecular Imaging of Inflammation in Atherosclerosis

(2013) Moritz Wildgruber et al.   Theranostics

Cationic PAMAM Dendrimers Aggressively Initiate Blood Clot Formation

(2012) Clinton F. Jones et al.   ACS Nano

Acute and Chronic Shear Stress Differently Regulate Endothelial Internalization of Nanocarriers Targeted to Platelet-Endothelial Cell Adhesion Molecule-1

(2012) Jingyan Han et al.   ACS Nano

Platelet Mimetic Particles for Targeting Thrombi in Flowing Blood

(2012) Nishit Doshi et al.   ADVANCED MATERIALS

Visualization of Vascular Inflammation in the Atherosclerotic Mouse by Ultrasmall Superparamagnetic Iron Oxide Vascular Cell Adhesion Molecule-1–Specific Nanoparticles

(2012) Marta Michalska et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A tissue factor targeted nanomedical system for thrombi-specific drug delivery

(2012) Wei Shi et al.   BIOMATERIALS

The antithrombotic and antimicrobial properties of PEG-protected silver nanoparticle coated surfaces

(2012) V.M. Ragaseema et al.   BIOMATERIALS

Potential fluid mechanic pathways of platelet activation

(2012) Shawn C. Shadden et al.   Biomechanics and Modeling in Mechanobiology

Microfabrication of cylindrical microfluidic channel networks for microvascular research

(2012) Zhouchun Huang et al.   BIOMEDICAL MICRODEVICES

Platelets can enhance vascular permeability

(2012) N. Cloutier et al.   BLOOD

Molecular Imaging of Atherosclerosis for Improving Diagnostic and Therapeutic Development

(2012) Thibaut Quillard et al.   CIRCULATION RESEARCH

The use of quartz crystal microbalance with dissipation (QCM-D) for studying nanoparticle-induced platelet aggregation

(2012) Santos-Martinez et al.   International Journal of Nanomedicine

Anin vitroassessment of the interaction of cadmium selenide quantum dots with DNA, iron, and blood platelets

(2012) Rekha Dunpall et al.   IUBMB LIFE

Particle-cell dynamics in human blood flow: Implications for vascular-targeted drug delivery

(2012) Phapanin Charoenphol et al.   JOURNAL OF BIOMECHANICS

The effect of novel magnetic nanoparticles on vascular endothelial cell function in vitro and in vivo

(2012) Le Su et al.   JOURNAL OF HAZARDOUS MATERIALS

Fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes rescue thrombocytopenic rabbits from non-compressible liver hemorrhage

(2012) K. NISHIKAWA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Contribution of platelet vs. endothelial VWF to platelet adhesion and hemostasis

(2012) S. KANAJI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Induction of platelet aggregation after a direct physical interaction with diesel exhaust particles

(2012) A. SOLOMON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Cationic PAMAM Dendrimers Disrupt Key Platelet Functions

(2012) Clinton F. Jones et al.   MOLECULAR PHARMACEUTICS

Development of screening assays for nanoparticle toxicity assessment in human blood: preliminary studies with charged Au nanoparticles

(2012) Sara A Love et al.   Nanomedicine

Research Highlights: Highlights from the latest articles in Nanomedicine

(2012) Israel Rubinstein   Nanomedicine

Nanoparticles induce platelet activation in vitro through stimulation of canonical signalling pathways

(2012) Gianni F. Guidetti et al.   Nanomedicine-Nanotechnology Biology and Medicine

From particle to platelet: Optimization of a stable, high brightness fluorescent nanoparticle based cell detection platform

(2012) R. Woolley et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cytotoxicity, oxidative stress and expression of adhesion molecules in human umbilical vein endothelial cells exposed to dust from paints with or without nanoparticles

(2012) Lone Mikkelsen et al.   Nanotoxicology

pH-controlled delivery of luminescent europium coated nanoparticles into platelets

(2012) A. Davies et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro microvessels for the study of angiogenesis and thrombosis

(2012) Y. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels

(2012) N. Korin et al.   SCIENCE

Carbon black nanoparticles and vascular dysfunction in cultured endothelial cells and artery segments

(2012) Lise K. Vesterdal et al.   TOXICOLOGY LETTERS

Analysis of platelet function: role of microfluidics and nanodevices

(2011) María José Santos-Martínez et al.   ANALYST

Approaches to the safety assessment of engineered nanomaterials (ENM) in food

(2011) Andrew Cockburn et al.   FOOD AND CHEMICAL TOXICOLOGY

Polystyrene nanoparticles activate ion transport in human airway epithelial cells

(2011) Joanna McCarthy et al.   International Journal of Nanomedicine

Biodegradable nanoparticles mimicking platelet binding as a targeted and controlled drug delivery system

(2011) Soujanya Kona et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology

(2011) Michelle Tsai et al.   JOURNAL OF CLINICAL INVESTIGATION

Nanoparticle Size and Surface Charge Determine Effects of PAMAM Dendrimers on Human Platelets in Vitro

(2011) Marina A. Dobrovolskaia et al.   MOLECULAR PHARMACEUTICS

Iron core/shell nanoparticles as magnetic drug carriers: possible interactions with the vascular compartment

(2011) Inge K Herrmann et al.   Nanomedicine

Multistability in platelets and their response to gold nanoparticles

(2011) Suryyani Deb et al.   Nanomedicine-Nanotechnology Biology and Medicine

Development of a method for magnetic labeling of platelets

(2011) Konstanze Aurich et al.   Nanomedicine-Nanotechnology Biology and Medicine

Arterial thrombosis—insidious, unpredictable and deadly

(2011) Shaun P Jackson   NATURE MEDICINE

Endothelial glycocalyx thickness and platelet-vessel wall interactions during atherogenesis

(2011) Mirjam oude Egbrink et al.   THROMBOSIS AND HAEMOSTASIS

Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis

(2011) Mo-Tao Zhu et al.   TOXICOLOGY LETTERS

Effect of mechanical factors on the function of engineered human blood microvessels in microfluidic collagen gels

(2010) Gavrielle M. Price et al.   BIOMATERIALS

The role of cyclic AMP in normalizing the function of engineered human blood microvessels in microfluidic collagen gels

(2010) Keith H.K. Wong et al.   BIOMATERIALS

Magnetic and Contrast Properties of Labeled Platelets for Magnetomotive Optical Coherence Tomography

(2010) Amy L. Oldenburg et al.   BIOPHYSICAL JOURNAL

Elucidation of flow-mediated tumour cell-induced platelet aggregation using an ultrasound standing wave trap

(2010) D Bazou et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulators of Platelet cAMP Levels: Clinical and Therapeutic Implications

(2010) L. Noe et al.   CURRENT MEDICINAL CHEMISTRY

Biological Properties of Iron Oxide Nanoparticles for Cellular and Molecular Magnetic Resonance Imaging

(2010) Thomas Schlorf et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comprehensive Biochemical Analysis of Rare Prostacyclin Receptor Variants

(2010) Jeremiah Stitham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Procoagulant properties of bare and highly PEGylated vinyl-modified silica nanoparticles

(2010) Regina Tavano et al.   Nanomedicine

Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity

(2010) Eun-Ah Jun et al.   Nanotoxicology

Influence of size, surface area and microporosity on thein vitrocytotoxic activity of amorphous silica nanoparticles in different cell types

(2010) Virginie Rabolli et al.   Nanotoxicology

Nanomedicine

(2010) Betty Y.S. Kim et al.   NEW ENGLAND JOURNAL OF MEDICINE

Roles of prostanoids in the pathogenesis of cardiovascular diseases: Novel insights from knockout mouse studies

(2010) Koh-ichi Yuhki et al.   PHARMACOLOGY & THERAPEUTICS

Surface Derivatization State of Polystyrene Latex Nanoparticles Determines both Their Potency and Their Mechanism of Causing Human Platelet Aggregation In Vitro

(2010) C. McGuinnes et al.   TOXICOLOGICAL SCIENCES

Disruption and Activation of Blood Platelets in Contact with an Antimicrobial Composite Coating Consisting of a Pyridinium Polymer and AgBr Nanoparticles

(2009) Kris N. Stevens et al.   ACS Applied Materials & Interfaces

Characterization of Antiplatelet Properties of Silver Nanoparticles

(2009) Siddhartha Shrivastava et al.   ACS Nano

Novel Platelet Substitutes: Disk-Shaped Biodegradable Nanosheets and their Enhanced Effects on Platelet Aggregation

(2009) Yosuke Okamura et al.   BIOCONJUGATE CHEMISTRY

Platelet functions beyond hemostasis

(2009) S. S. SMYTH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet Adhesion under Flow

(2009) Zaverio M. Ruggeri   MICROCIRCULATION

Biologic nanoparticles and platelet reactivity

(2009) Virginia M Miller et al.   Nanomedicine

Platelet compatibility of PLGA, chitosan and PLGA–chitosan nanoparticles

(2009) Xue Li et al.   Nanomedicine

Intravenous Hemostat: Nanotechnology to Halt Bleeding

(2009) J. P. Bertram et al.   Science Translational Medicine

Contribution of biologically derived nanoparticles to disease

(2009) Maria K. Schwartz et al.   SURGERY

The role of nanoparticle size in hemocompatibility

(2009) Andrea Mayer et al.   TOXICOLOGY

Single-walled carbon nanotubes activate platelets and accelerate thrombus formation in the microcirculation

(2009) Peter Bihari et al.   TOXICOLOGY

Interactions between Multiple Cell Types in Parallel Microfluidic Channels: Monitoring Platelet Adhesion to an Endothelium in the Presence of an Anti-Adhesion Drug

(2008) Chia-Jui Ku et al.   ANALYTICAL CHEMISTRY

Magnetic Resonance Imaging Contrast Agent Targeted Toward Activated Platelets Allows In Vivo Detection of Thrombosis and Monitoring of Thrombolysis

(2008) C. von zur Muhlen et al.   CIRCULATION

Direct Impairment of Vascular Function by Diesel Exhaust Particulate through Reduced Bioavailability of Endothelium-Derived Nitric Oxide Induced by Superoxide Free Radicals

(2008) Mark R. Miller et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Matrix metalloproteinases in platelet function: coming of age

(2008) M. J. SANTOS-MARTINEZ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelets, Petechiae, and Preservation of the Vascular Wall

(2008) Ralph L. Nachman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticles: pharmacological and toxicological significance

(2007) C Medina et al.   BRITISH JOURNAL OF PHARMACOLOGY