Article
Nutrition & Dietetics
Martin N. Mwangi, Dennis G. A. B. Oonincx, Marijke Hummel, Dessy A. Utami, Lidyawati Gunawan, Margot Veenenbos, Christophe Zeder, Colin Cercamondi, Michael B. Zimmermann, Joop J. A. van Loon, Marcel Dicke, Alida Melse-Boonstra
Summary: This study assessed the absorption of iron from edible crickets in humans. The results showed that iron absorption was lower from crickets consumed with refined maize porridge, possibly due to the presence of chitin and other inhibitors in the cricket biomass.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Gabriela Burgos, Reyna Liria, Christophe Zeder, Paul A. Kroon, Guy Hareau, Mary Penny, Jack Dainty, Olla Al-Jaibaji, Erick Boy, Richard Mithen, Richard F. Hurrell, Elisa Salas, Thomas zum Felde, Michael B. Zimmermann, Susan Fairweather-Tait
Summary: A study found that iron absorption from iron-biofortified yellow-fleshed potatoes is higher compared to non-biofortified potatoes, suggesting that biofortification of potatoes through conventional breeding can improve iron intake in iron-deficient women.
JOURNAL OF NUTRITION
(2023)
Article
Hematology
Cornelia Speich, Rita Wegmueller, Gary M. Brittenham, Christophe Zeder, Colin Cercamondi, Daniela Buhl, Andrew M. Prentice, Michael B. Zimmermann, Diego Moretti
Summary: This study presents the first measurements of long-term iron absorption and loss during iron supplementation in African children using a stable isotope of iron (Fe-57). The results showed that both iron absorption and loss significantly increased during the supplementation period, with most of the absorbed iron being lost.
BRITISH JOURNAL OF HAEMATOLOGY
(2021)
Article
Nutrition & Dietetics
Rajib Podder, Raymond P. Glahn, Albert Vandenberg
Summary: The study demonstrated that dual-fortified lentils have higher levels of iron and zinc, lower phytic acid concentration, and increased relative iron bioavailability. After 1 year of storage, there was a slight decrease in iron, zinc, and relative iron bioavailability in the samples, with changes in phytic acid concentration.
FRONTIERS IN NUTRITION
(2021)
Review
Biochemistry & Molecular Biology
Andrew G. Hall, Janet C. King
Summary: Zinc is a crucial nutrient with a lack of understanding in its deficiency. Recent advances have shed light on its chemistry and molecular roles, but there is a lack of research on the molecular basis of zinc bioavailability. This review aims to merge the concepts of zinc molecular biology and bioavailability, focusing on the molecular determinants of zinc's availability, absorption, transport, and utilization.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Plant Sciences
Johanna I. I. Keigler, Jason A. A. Wiesinger, Sherry A. A. Flint-Garcia, Raymond P. P. Glahn
Summary: Maize is a staple food for communities with high levels of anemia, and enhancing its iron bioavailability through degermination could help alleviate iron deficiency. This study evaluated the effects of degermination on iron bioavailability in 52 diverse maize genotypes, showing that it increased in 30 genotypes while remaining unchanged or decreasing in the other 22. Phytate concentrations in maize flours were also reduced with degermination, but the relationship between phytate concentrations and iron bioavailability was complex.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Agriculture, Multidisciplinary
Zhenglin Dong, Lan Li, Yiming Zhang, Liu Guo, Xin Wu, Yulong Yin, Dan Wan
Summary: Circadian iron administration affected iron absorption and storage in pigs. Evening iron supplementation may be a more effective pattern for iron utilization. The rhythmic system in the intestine, driven by the time, played an important role in this process.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Nutrition & Dietetics
Reyna Liria-Dominguez, Mary Penny, Paul Antony Kroon, Gabriela Burgos, Jack Dainty, Christophe Zeder, Michael B. Zimmermann, Janet King, Richard Mithen, Erick Boy, Olla Al-Jaiballi, Susan Fairweather-Tait
Summary: The study found that zinc-biofortified potatoes provide more absorbable zinc compared to regular potatoes. These biofortified potatoes could help reduce zinc deficiency in populations where potatoes are a staple food.
JOURNAL OF NUTRITION
(2023)
Article
Nutrition & Dietetics
Meryem Lazrak, Khalid El Kari, Nicole U. Stoffel, Laila Elammari, Ayoub Al-Jawaldeh, Cornelia U. Loechl, Abdelhakim Yahyane, Amina Barkat, Michael B. Zimmermann, Hassan Aguenaou
Summary: Polyphenols from tea can inhibit iron absorption from NaFeEDTA, and this inhibition is observed in both nonanemic women and women with iron deficiency anemia (IDA). Tea consumption significantly reduces iron absorption from NaFeEDTA, regardless of anemia status.
JOURNAL OF NUTRITION
(2021)
Article
Food Science & Technology
Keith Lividini, William A. Masters
Summary: This study provides a comprehensive nutrient balance sheet of plant-based and animal-sourced food flows from farm production to trade, comparing the availability of nutrients with population nutrient requirements. The study identifies nutrient gaps and suggests possible solutions through food production, trade, fortification, and supplementation.
Article
Agriculture, Multidisciplinary
Vicente Agullo, Diego A. Moreno, Raul Dominguez-Perles, Cristina Garcia-Viguera
Summary: This article reviews the contribution of different experimental approaches to the bioaccessibility, bioavailability, and bioactivity of (poly)phenols, and discusses the association between healthy/functional foods and the incidence of non-communicable diseases.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Nutrition & Dietetics
Nancy E. Moran, Joshua Wade, Rachel Stroh, Barbara Stoll, Gregory Guthrie, Amy B. Hair, Douglas G. Burrin
Summary: The study found that preterm pigs fed with donor human milk had higher concentrations of liver beta-carotene compared to those fed with premature infant formula. However, liver vitamin A stores were higher in pigs fed with infant formula. Additionally, plasma, liver, and jejunum concentrations of lutein, zeaxanthin, and lycopene were higher in pigs fed with donor human milk. The study suggests that further research should be conducted to investigate the bioactivity and bioavailability of carotenoids in infants.
JOURNAL OF NUTRITION
(2023)
Review
Food Science & Technology
Samantha L. L. Huey, Neel H. H. Mehta, Elsa M. M. Konieczynski, Arini Bhargava, Valerie M. M. Friesen, Jesse T. T. Krisher, Mduduzi N. N. Mbuya, Eva Monterrosa, Annette M. M. Nyangaresi, Erick Boy, Saurabh Mehta
Summary: This study examined the bioavailability of target micronutrients enriched in conventionally biofortified crops post-harvest storage and/or processing. Conventional biofortified crops generally had higher bioaccessibility and bioavailability compared to conventional counterparts, though the estimates varied depending on cultivar, processing method, context, and experimental method used.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Food Science & Technology
Shengjie Hu, Songyi Lin, Xueqing He, Na Sun
Summary: This review provides an overview of different iron delivery systems, including protein aggregates, amino acids, peptides, polysaccharides, liposomes, and microcapsules, and discusses their effects on iron release and absorption during gastrointestinal digestion.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Chemistry, Physical
Yuping Duan, Yuanyuan Fu, Yupeng Shi, Huifang Pang, Lingxi Huang
Summary: By using tetra-needle zinc oxide whisker as a structural template, the spatial distribution of flake carbonyl iron powders is managed, achieving temperature-stable broadband microwave absorption. Adjusting the filling content of the whisker changes the distribution of the powders, providing stable conductive paths and facilitating low temperature-sensitivity conductance loss. It also provides more transmission channels for electromagnetic waves and achieves excellent impedance matching.
APPLIED SURFACE SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Bartosz Fotschki, Jose Moises Laparra, Michal Sojka
Article
Cell Biology
Masa Srdic, Ivana Ovcina, Bartosz Fotschki, Claudia Monika Haros, Jose Moises Laparra Llopis
Article
Nutrition & Dietetics
Jose Moises Laparra Llopis, Daniel Brown, Blanca Saiz
Article
Plant Sciences
Raquel Selma-Gracia, Claudia Monika Haros, Jose Moises Laparra
PLANT FOODS FOR HUMAN NUTRITION
(2020)
Article
Nutrition & Dietetics
Bartosz Fotschki, Jerzy Juskiewicz, Adam Jurgonski, Ryszard Amarowicz, Paulina Opyd, Jurgen Bez, Isabel Muranyi, Iben Lykke Petersen, Moises Laparra Llopis
Article
Nutrition & Dietetics
Danuta Zielinska, Henryk Zielinski, Jose Moises Laparra-Llopis, Dorota Szawara-Nowak, Joanna Honke, Juan Antonio Gimenez-Bastida
Summary: The study showed that caffeic acid can modulate mechanisms related to intestinal inflammation by targeting COX-2, PGE(2) synthesis, and IL-8 biosynthesis. Additionally, it inhibits AGE formation, possibly due to its high chelating activity.
Article
Nutrition & Dietetics
Raquel Selma-Gracia, Polona Megusar, Claudia Monika Haros, Jose Moises Laparra Llopis
Summary: The study compared the effects of immunonutritional bioactives from quinoa and chia on high fat diet-induced insulin resistance. Results showed that these products improved hepatic lipid accumulation, glucose homeostasis, and normalized HOMA-IR. These positive effects were associated with positive variations in the peripheral myeloid cells population.
Review
Biochemistry & Molecular Biology
Victoria Fernandez-Garcia, Silvia Gonzalez-Ramos, Paloma Martin-Sanz, Jose M. Laparra, Lisardo Bosca
Summary: Immunonutrition is a promising field in modern medicine that aims to improve immune system functioning and individual immunity. NOD1, a member of innate immunity receptors, has been associated with various pathologies and could be a valuable target for research in immunonutrition. Understanding the cellular and molecular mechanisms modulating the immune system and involving NOD1 activation is crucial for developing specific and personalized nutrition strategies in conjunction with surgical or pharmacological treatments.
Article
Biochemistry & Molecular Biology
Bartosz Fotschki, Aurora Garcia Tejedor, Juan Antonio Nieto Fuentes, Jose Moises Laparra Llopis
Summary: This study evaluated the immunonutritional effects of protease inhibitors from Avena sativa and Triticum durum on human macrophage-like cells. The results showed that T. durum extracts had lower susceptibility to degradation by gastrointestinal enzymes and A. sativa extracts improved mitochondrial respiration. Despite their different botanical origins, both extracts increased TLR4 expression and triggered relative similar immune-metabolic events.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Juan Antonio Gimenez-Bastida, Antonio Gonzalez-Sarrias, Jose Moises Laparra-Llopis, Claus Schneider, Juan Carlos Espin
Summary: Dietary (poly)phenols demonstrate anti-inflammatory effects by targeting the 5-LOX pathway, although research in this area is limited and requires further exploration.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Adrian Bouzas Munoz, Juan Antonio Gimenez-Bastida, Aurora Garcia Tejedor, Claudia Monika Haros, Marta Gomez de Cedron, Ana Ramirez de Molina, Jose Moises Laparra Llopis
Summary: The study showed that administration of SETIs improved survival and decreased tumor burden by modulating monocyte-derived macrophages, playing a key role in diet-induced HCC development. This suggests a potential therapeutic strategy to improve the hepatic innate immune response and create a better antitumoral environment in early stages of HCC development.
Review
Biochemistry & Molecular Biology
Helena Marcos Pasero, Aurora Garcia Tejedor, Juan Antonio Gimenez-Bastida, Jose Moises Laparra Llopis
Summary: Alzheimer's disease is a inflammation-related cognitive decline, with the immune microenvironment playing a crucial role in its pathogenesis. Various peripheral stimuli are involved in the progression and severity of the disease. Targeting immune signals and cells is achievable, but more understanding of their contribution to the disease is needed for effective interventions. An integrative perspective can improve the health of AD patients.
Article
Food Science & Technology
Aurora Garcia Tejedor, Claudia Monika Haros, Jose Moises Laparra Llopis
Summary: This study investigated the effects of Chenopodium quinoa's ingredients on the hepatic profile of major lipids and the functional differentiation of monocyte-derived macrophages and innate lymphoid cells in mice on a high-fat diet. The results showed that feeding the mice with a low-molecular-weight protein fraction (LWPF) improved their ability to utilize fatty acids and reduced hepatic lipid accumulation, while feeding them the lipid fraction (qLF) had no effect on lipid accumulation. Therefore, Chenopodium quinoa's ingredients are advantageous for controlling hepatic lipotoxicity and promoting the expansion and functional differentiation of liver macrophages and innate lymphoid cells.
Article
Biochemistry & Molecular Biology
Raquel Selma-Gracia, Claudia Monika Haros, Jose Moises Laparra Llopis
Article
Biochemistry & Molecular Biology
J. M. Laparra, C. M. Haros