Phosphoinositide 3-kinase p110γ in immunity

Isoform-Specific Functions of Phosphoinositide 3-Kinases: p110  but Not p110  Promotes Optimal Allergic Responses In Vivo

(2014) K. Ali et al.   JOURNAL OF IMMUNOLOGY

Targeting Phosphoinositide-3-Kinase-δ with Theophylline Reverses Corticosteroid Insensitivity in Chronic Obstructive Pulmonary Disease

(2010) Yasuo To et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Phosphoinositide-3 Kinase γ Activity Contributes to Sepsis and Organ Damage by Altering Neutrophil Recruitment

(2010) Erica L. Martin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Phosphoinositide 3-kinase-gamma expression is upregulated in brain microglia and contributes to ischemia-induced microglial activation in acute experimental stroke

(2010) Rong Jin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A phosphoinositide 3-kinase-γ inhibitor, AS605240 prevents bleomycin-induced pulmonary fibrosis in rats

(2010) Xin Wei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of phosphoinositide 3-kinase γ decreases migration and activation of phagocytes but not T cell activation in antigen-induced arthritis

(2010) Michael Gruen et al.   BMC MUSCULOSKELETAL DISORDERS

Ventilator-induced lung injury: The anatomical and physiological framework

(2010) Luciano Gattinoni et al.   CRITICAL CARE MEDICINE

Differential Regulation of Protrusion and Polarity by PI(3)K during Neutrophil Motility in Live Zebrafish

(2010) Sa Kan Yoo et al.   DEVELOPMENTAL CELL

Pulmonary-derived phosphoinositide 3-kinase gamma (PI3Kγ) contributes to ventilator-induced lung injury and edema

(2010) Vito Fanelli et al.   INTENSIVE CARE MEDICINE

Phosphoinositide 3-kinase γ mediates chemotactic responses of human eosinophils to platelet-activating factor

(2010) Anwar Matar Hasan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Btk-dependent Rac activation and actin rearrangement following Fc RI aggregation promotes enhanced chemotactic responses of mast cells

(2010) H. S. Kuehn et al.   JOURNAL OF CELL SCIENCE

Phosphoinositide 3-kinase γ plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice

(2010) Remo C. Russo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Absence of PI3Kγ leads to increased leukocyte apoptosis and diminished severity of experimental autoimmune encephalomyelitis

(2010) David Henrique Rodrigues et al.   JOURNAL OF NEUROIMMUNOLOGY

Involvement of phosphoinositide 3-kinase γ in the neuro-inflammatory response and cognitive impairments induced by β-amyloid 1–40 peptide in mice

(2009) Giselle F. Passos et al.   BRAIN BEHAVIOR AND IMMUNITY

PI3Kγ regulates cartilage damage in chronic inflammatory arthritis

(2009) Silvia Hayer et al.   FASEB JOURNAL

PI3Kγ Differentially Regulates FcεRI-Mediated Degranulation and Migration of Mast Cells by and toward Antigen

(2009) Daisuke Endo et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Allergic airway hyperresponsiveness, inflammation, and remodeling do not develop in phosphoinositide 3-kinase γ–deficient mice

(2009) Masahide Takeda et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inhibition of Phosphoinositide 3-Kinase Ameliorates Dextran Sodium Sulfate-Induced Colitis in Mice

(2009) X.-d. Peng et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

PI3K  Adaptor Subunits Define Coupling to Degranulation and Cell Motility by Distinct PtdIns(3,4,5)P3 Pools in Mast Cells

(2009) T. Bohnacker et al.   Science Signaling

PI3Kγ-deficient mice have reduced levels of allergen-induced eosinophilic inflammation and airway remodeling

(2008) Dae Hyun Lim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

PI3Kγ controls oxidative bursts in neutrophils via interactions with PKCα and p47phox

(2008) Katja Lehmann et al.   BIOCHEMICAL JOURNAL

PI3Kgamma (PI3K ) is essential for efficient induction of CXCR3 on activated T cells

(2008) J. Barbi et al.   BLOOD

Essential role of phosphoinositide 3-kinase gamma in eosinophil chemotaxis within acute pulmonary inflammation

(2008) Matthew Thomas et al.   IMMUNOLOGY

Comprehensive Identification of PIP3-Regulated PH Domains from C. elegans to H. sapiens by Model Prediction and Live Imaging

(2008) Wei Sun Park et al.   MOLECULAR CELL

Phosphoinositide 3-Kinase γ Gene Knockout Impairs Postischemic Neovascularization and Endothelial Progenitor Cell Functions

(2007) Paolo Madeddu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY