Molecular systems evaluation of oligomerogenic APP E693Q and fibrillogenic APP KM670/671NL /PSEN1 Δexon9 mouse models identifies shared features with human Alzheimer’s brain molecular pathology

Tau Phosphorylated at Tyrosine 394 is Found in Alzheimer's Disease Tangles and can be a Product of the Abl-Related Kinase, Arg

(2017) Matthew A. Tremblay et al.   JOURNAL OF ALZHEIMERS DISEASE

Mouse models rarely mimic the transcriptome of human neurodegenerative diseases: A systematic bioinformatics-based critique of preclinical models

(2015) Terry C. Burns et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia

(2015) Willemijn J. Jansen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Neuroinflammatory Signals in Alzheimer Disease and APP/PS1 Transgenic Mice

(2015) Irene López-González et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease

(2015) Elizabeta Gjoneska et al.   NATURE

Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Like Pathology

(2015) Marie-Victoire Guillot-Sestier et al.   NEURON

IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque Burden and Worsening Cognitive Behavior

(2015) Paramita Chakrabarty et al.   NEURON

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

A Genome-wide Gene-Expression Analysis and Database in Transgenic Mice during Development of Amyloid or Tau Pathology

(2015) Mar Matarin et al.   Cell Reports

Association of Brain DNA Methylation inSORL1,ABCA7,HLA-DRB5,SLC24A4, andBIN1With Pathological Diagnosis of Alzheimer Disease

(2015) Lei Yu et al.   JAMA Neurology

Elucidating Molecular Mass and Shape of a Neurotoxic Aβ Oligomer

(2014) Adriano Sebollela et al.   ACS Chemical Neuroscience

Altered synaptic structure in the hippocampus in a mouse model of Alzheimer’s disease with soluble amyloid-β oligomers and no plaque pathology

(2014) Katherine A Price et al.   Molecular Neurodegeneration

Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse

(2014) S H Kim et al.   MOLECULAR PSYCHIATRY

A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly

(2014) V Chouraki et al.   MOLECULAR PSYCHIATRY

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

(2014) Katie Lunnon et al.   NATURE NEUROSCIENCE

The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease

(2014) Janan T. Eppig et al.   NUCLEIC ACIDS RESEARCH

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

(2014) Charity W Law et al.   GENOME BIOLOGY

Fragile X mental retardation protein expression in Alzheimer’s disease

(2014) Abigail J. Renoux et al.   Frontiers in Genetics

Toward the Treatment and Prevention of Alzheimer's Disease: Rational Strategies and Recent Progress

(2013) Sam Gandy et al.   Annual Review of Medicine

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

Calculating Sample Size Estimates for RNA Sequencing Data

(2013) Steven N. Hart et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Microglial Activation Milieu Controls Regulatory T Cell Responses

(2013) F. Ebner et al.   JOURNAL OF IMMUNOLOGY

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Short-term treatment with tolfenamic acid improves cognitive functions in Alzheimer's disease mice

(2013) Gehad M. Subaiea et al.   NEUROBIOLOGY OF AGING

ADAM10 Missense Mutations Potentiate β-Amyloid Accumulation by Impairing Prodomain Chaperone Function

(2013) Jaehong Suh et al.   NEURON

Microglia as Dynamic and Essential Components of the Amyloid Hypothesis

(2013) Sam Gandy et al.   NEURON

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

(2013) Ana Griciuc et al.   NEURON

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

Data, information, knowledge and principle: back to metabolism in KEGG

(2013) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Neurochemical mapping of the human hippocampus reveals perisynaptic matrix around functional synapses in Alzheimer’s disease

(2012) Dávid Lendvai et al.   ACTA NEUROPATHOLOGICA

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Detecting differential usage of exons from RNA-seq data

(2012) S. Anders et al.   GENOME RESEARCH

SUMO1 modulates Aβ generation via BACE1 accumulation

(2012) Sang-Moon Yun et al.   NEUROBIOLOGY OF AGING

Lifelong Management of Amyloid-Beta Metabolism to Prevent Alzheimer's Disease

(2012) Sam Gandy   NEW ENGLAND JOURNAL OF MEDICINE

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Expression2Kinases: mRNA profiling linked to multiple upstream regulatory layers

(2011) Edward Y. Chen et al.   BIOINFORMATICS

Strategies for aggregating gene expression data: The collapseRows R function

(2011) Jeremy A Miller et al.   BMC BIOINFORMATICS

Perspective: Prevention is better than cure

(2011) Sam Gandy   NATURE

Reversal of Fragile X Phenotypes by Manipulation of AβPP/Aβ Levels in Fmr1KO Mice

(2011) Cara J. Westmark et al.   PLoS One

Heparan Sulfate Proteoglycans

(2011) S. Sarrazin et al.   Cold Spring Harbor Perspectives in Biology

ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments

(2010) Alexander Lachmann et al.   BIOINFORMATICS

The Disintegrin/Metalloproteinase ADAM10 Is Essential for the Establishment of the Brain Cortex

(2010) E. Jorissen et al.   JOURNAL OF NEUROSCIENCE

Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid-  Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex

(2010) R. F. Lane et al.   JOURNAL OF NEUROSCIENCE

GAGE: generally applicable gene set enrichment for pathway analysis

(2009) Weijun Luo et al.   BMC BIOINFORMATICS

Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts

(2009) W. D. Bradley et al.   JOURNAL OF CELL SCIENCE

Molecular networks as sensors and drivers of common human diseases

(2009) Eric E. Schadt   NATURE

Genome screen of late-onset Alzheimer's extended pedigrees identifies TRPC4AP by haplotype analysis

(2008) S.E. Poduslo et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Epigenetic Silencing of CCAAT/Enhancer-binding Protein δ Activity by YY1/Polycomb Group/DNA Methyltransferase Complex

(2008) Chiung-Yuan Ko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set

(2008) Winnie S. Liang et al.   PHYSIOLOGICAL GENOMICS