Toward the Treatment and Prevention of Alzheimer's Disease: Rational Strategies and Recent Progress
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Toward the Treatment and Prevention of Alzheimer's Disease: Rational Strategies and Recent Progress
Authors
Keywords
-
Journal
Annual Review of Medicine
Volume 64, Issue 1, Pages 367-383
Publisher
Annual Reviews
Online
2013-01-18
DOI
10.1146/annurev-med-092611-084441
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Early AD pathology in a [C-11]PiB-negative case: a PiB-amyloid imaging, biochemical, and immunohistochemical study
- (2012) Milos D. Ikonomovic et al. ACTA NEUROPATHOLOGICA
- Three-year follow-up on the IVIg for Alzheimer's phase II study
- (2012) Norman Relkin et al. Alzheimers & Dementia
- Development of an induced pluripotent stem cell (iPSC) Alzheimer's disease model using PSEN1 mutant fibroblasts
- (2012) Andrew Sproul et al. Alzheimers & Dementia
- Exercise Engagement as a Moderator of the Effects of APOE Genotype on Amyloid Deposition
- (2012) Julie M. Bugg ARCHIVES OF NEUROLOGY
- Effects of Membrane Lipids on the Activity and Processivity of Purified γ-Secretase
- (2012) Oliver Holmes et al. BIOCHEMISTRY
- iPSCs to the Rescue in Alzheimer's Research
- (2012) Se Hoon Choi et al. Cell Stem Cell
- Dementia From Alzheimer Disease and Mixed Pathologies in the Oldest Old
- (2012) Bryan D. James JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing
- (2012) A. W. Fjorback et al. JOURNAL OF NEUROSCIENCE
- Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study
- (2012) Christopher M Clark et al. LANCET NEUROLOGY
- Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model
- (2012) J W Steele et al. MOLECULAR PSYCHIATRY
- High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease
- (2012) C Pottier et al. MOLECULAR PSYCHIATRY
- Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain
- (2012) J W Steele et al. MOLECULAR PSYCHIATRY
- Active vaccination with ankyrin G reduces β-amyloid pathology in APP transgenic mice
- (2012) A C Santuccione et al. MOLECULAR PSYCHIATRY
- A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline
- (2012) Thorlakur Jonsson et al. NATURE
- Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
- (2012) Congcong He et al. NATURE
- Low PiB PET retention in presence of pathologic CSF biomarkers in Arctic APP mutation carriers
- (2012) M. Scholl et al. NEUROLOGY
- Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
- (2012) Alix de Calignon et al. NEURON
- The Ethics of Early Evidence — Preparing for a Possible Breakthrough in Alzheimer's Disease
- (2012) Justin Lowenthal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease
- (2012) Randall J. Bateman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Trans-Synaptic Spread of Tau Pathology In Vivo
- (2012) Li Liu et al. PLoS One
- ApoE-Directed Therapeutics Rapidly Clear -Amyloid and Reverse Deficits in AD Mouse Models
- (2012) P. E. Cramer et al. SCIENCE
- APOE 4 Status and Traumatic Brain Injury on the Gridiron or the Battlefield
- (2012) S. Gandy et al. Science Translational Medicine
- Revision of the criteria for Alzheimer's disease: A symposium
- (2011) Steven T. DeKosky et al. Alzheimers & Dementia
- The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Guy M. McKhann et al. Alzheimers & Dementia
- The Alzheimer’s Disease Neuroimaging Initiative: A review of papers published since its inception
- (2011) Michael W. Weiner et al. Alzheimers & Dementia
- Six-Month Walking Program Changes Cognitive and ADL Performance in Patients With Alzheimer
- (2011) Massimo Venturelli et al. American Journal of Alzheimers Disease and Other Dementias
- Mild Cognitive Impairment, Dementia, and Their Subtypes in Oldest Old Women
- (2011) Kristine Yaffe et al. ARCHIVES OF NEUROLOGY
- Cholesterol Level and Statin Use in Alzheimer Disease
- (2011) Nina E. Shepardson ARCHIVES OF NEUROLOGY
- Cholesterol Level and Statin Use in Alzheimer Disease
- (2011) Nina E. Shepardson ARCHIVES OF NEUROLOGY
- Dissociation between the Processivity and Total Activity of γ-Secretase: Implications for the Mechanism of Alzheimer's Disease-Causing Presenilin Mutations
- (2011) Omar Quintero-Monzon et al. BIOCHEMISTRY
- RETRACTED: Directed Conversion of Alzheimer's Disease Patient Skin Fibroblasts into Functional Neurons
- (2011) Liang Qiang et al. CELL
- Perspective: Prevention is better than cure
- (2011) Sam Gandy NATURE
- Review: Contact sport-related chronic traumatic encephalopathy in the elderly: clinical expression and structural substrates
- (2011) A. Costanza et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Chronic traumatic encephalopathy in an Iraqi war veteran with posttraumatic stress disorder who committed suicide
- (2011) Bennet Omalu et al. Neurosurgical Focus
- Alzheimer's Disease and Non-Demented High Pathology Control Nonagenarians: Comparing and Contrasting the Biochemistry of Cognitively Successful Aging
- (2011) Chera L. Maarouf et al. PLoS One
- Genome-Wide Analysis of a Wnt1-Regulated Transcriptional Network Implicates Neurodegenerative Pathways
- (2011) E. M. Wexler et al. Science Signaling
- A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid- Production in Vivo
- (2011) J. K. Atwal et al. Science Translational Medicine
- Testing the Right Target and Right Drug at the Right Stage
- (2011) R. A. Sperling et al. Science Translational Medicine
- Human apoE Isoforms Differentially Regulate Brain Amyloid- Peptide Clearance
- (2011) J. M. Castellano et al. Science Translational Medicine
- Validation of Consensus Panel Diagnosis in Dementia
- (2010) Matthew J. Gabel et al. ARCHIVES OF NEUROLOGY
- Diagnosis-Independent Alzheimer Disease Biomarker Signature in Cognitively Normal Elderly People
- (2010) Geert De Meyer ARCHIVES OF NEUROLOGY
- Life span extension by resveratrol, rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy aging
- (2010) Laurent Mouchiroud et al. BIOFACTORS
- Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid- Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex
- (2010) R. F. Lane et al. JOURNAL OF NEUROSCIENCE
- Testing the amyloid hypothesis of Alzheimer's disease in vivo
- (2010) Sam Gandy LANCET NEUROLOGY
- Revising the definition of Alzheimer's disease: a new lexicon
- (2010) Bruno Dubois et al. LANCET NEUROLOGY
- 11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study
- (2010) Juha O Rinne et al. LANCET NEUROLOGY
- Amyloid-β Oligomers: Possible Roles as Key Neurotoxins in Alzheimer's Disease
- (2010) Alex L. Lublin et al. MOUNT SINAI JOURNAL OF MEDICINE
- Gamma-secretase activating protein is a therapeutic target for Alzheimer’s disease
- (2010) Gen He et al. NATURE
- The Genetics of Alzheimer Disease: Back to the Future
- (2010) Lars Bertram et al. NEURON
- Traumatic Brain Injury — Football, Warfare, and Long-Term Effects
- (2010) Steven T. DeKosky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chronic traumatic encephalopathy in a professional American wrestler
- (2010) Bennet I. Omalu et al. Journal of Forensic Nursing
- Absence of Pittsburgh Compound B Detection of Cerebral Amyloid β in a Patient With Clinical, Cognitive, and Cerebrospinal Fluid Markers of Alzheimer Disease
- (2009) Nigel J. Cairns et al. ARCHIVES OF NEUROLOGY
- Ginkgo biloba for Preventing Cognitive Decline in Older AdultsA Randomized Trial
- (2009) Beth E. Snitz JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Transmission and spreading of tauopathy in transgenic mouse brain
- (2009) Florence Clavaguera et al. NATURE CELL BIOLOGY
- APOE 4 and bapineuzumab: Infusing pharmacogenomics into Alzheimer disease therapeutics
- (2009) D. Kaufer et al. NEUROLOGY
- A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease
- (2009) S. Salloway et al. NEUROLOGY
- The Role of Apolipoprotein E in Alzheimer's Disease
- (2009) Jungsu Kim et al. NEURON
- Natural human antibodies to amyloid beta peptide
- (2008) Paul Szabo et al. AUTOIMMUNITY REVIEWS
- Long-term reversal of cholinergic neuronal decline in aged non-human primates by lentiviral NGF gene delivery
- (2008) Alan H. Nagahara et al. EXPERIMENTAL NEUROLOGY
- apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain
- (2008) Rashid Deane et al. JOURNAL OF CLINICAL INVESTIGATION
- Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study
- (2008) Rachelle S Doody et al. LANCET
- 18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease
- (2008) Norman R. Relkin et al. NEUROBIOLOGY OF AGING
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now