Host Defense at the Ocular Surface

Flagellin Treatment Protects against Chemicals, Bacteria, Viruses, and Radiation

(2014) M. Vijay-Kumar et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Membrane Nanotubes In Vivo: A Feature of MHC Class II + Cells in the Mouse Cornea

(2014) Holly R. Chinnery et al.   JOURNAL OF IMMUNOLOGY

Trachoma

(2012) Satasuk Joy Bhosai et al.   CURRENT OPINION IN OPHTHALMOLOGY

The role of cytokines and pathogen recognition molecules in fungal keratitis – Insights from human disease and animal models

(2012) Sixto M. Leal et al.   CYTOKINE

Fungal antioxidant pathways promote survival against neutrophils during infection

(2012) Sixto M. Leal et al.   JOURNAL OF CLINICAL INVESTIGATION

Cytokeratins mediate epithelial innate defense through their antimicrobial properties

(2012) Connie Tam et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: IL-1β Processing during Pseudomonas aeruginosa Infection Is Mediated by Neutrophil Serine Proteases and Is Independent of NLRC4 and Caspase-1

(2012) Mausita Karmakar et al.   JOURNAL OF IMMUNOLOGY

ExoS and ExoT ADP Ribosyltransferase Activities Mediate Pseudomonas aeruginosa Keratitis by Promoting Neutrophil Apoptosis and Bacterial Survival

(2012) Y. Sun et al.   JOURNAL OF IMMUNOLOGY

Toll-like Receptors at the Ocular Surface

(2012) Eric Pearlman et al.   Ocular Surface

Tear Lipocalin: structure and Function

(2012) Darlene A. Dartt   Ocular Surface

TLR9 Ligand CpG-ODN Applied to the Injured Mouse Cornea Elicits Retinal Inflammation

(2011) Holly R. Chinnery et al.   AMERICAN JOURNAL OF PATHOLOGY

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

Onchocerciasis: the Role of Wolbachia Bacterial Endosymbionts in Parasite Biology, Disease Pathogenesis, and Treatment

(2011) F. Tamarozzi et al.   CLINICAL MICROBIOLOGY REVIEWS

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils

(2011) Arun K. Mankan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Toll-like receptor activation modulates antimicrobial peptide expression by ocular surface cells

(2011) Rachel L. Redfern et al.   EXPERIMENTAL EYE RESEARCH

The inflammasome: an integrated view

(2011) Olaf Gross et al.   IMMUNOLOGICAL REVIEWS

Interferon-γ-induced MD-2 Protein Expression and Lipopolysaccharide (LPS) Responsiveness in Corneal Epithelial Cells Is Mediated by Janus Tyrosine Kinase-2 Activation and Direct Binding of STAT1 Protein to the MD-2 Promoter

(2011) Sanhita Roy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ocular Neovascularization Caused by Herpes Simplex Virus Type 1 Infection Results from Breakdown of Binding between Vascular Endothelial Growth Factor A and Its Soluble Receptor

(2011) A. Suryawanshi et al.   JOURNAL OF IMMUNOLOGY

Expression of Innate and Adaptive Immune Mediators in Human Corneal Tissue Infected With Aspergillus or Fusarium

(2011) Rajapandian Sivaganesa Karthikeyan et al.   JOURNAL OF INFECTIOUS DISEASES

A Novel Role for the NLRC4 Inflammasome in Mucosal Defenses against the Fungal Pathogen Candida albicans

(2011) Jeffrey Tomalka et al.   PLoS Pathogens

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Membrane-tethered mucins have multiple functions on the ocular surface

(2010) Bharathi Govindarajan et al.   EXPERIMENTAL EYE RESEARCH

Microbial Contamination of Contact Lenses, Lens Care Solutions, and Their Accessories: A Literature Review

(2010) Loretta B. Szczotka-Flynn et al.   Eye & Contact Lens-Science and Clinical Practice

The ADP-Ribosylation Domain of Pseudomonas aeruginosa ExoS Is Required for Membrane Bleb Niche Formation and Bacterial Survival within Epithelial Cells

(2010) A. A. Angus et al.   INFECTION AND IMMUNITY

Role of Defensins in Corneal Epithelial Barrier Function againstPseudomonas aeruginosaTraversal

(2010) Danielle K. Augustin et al.   INFECTION AND IMMUNITY

TLR4 and TLR5 on Corneal Macrophages Regulate Pseudomonas aeruginosa Keratitis by Signaling through MyD88-Dependent and -Independent Pathways

(2010) Y. Sun et al.   JOURNAL OF IMMUNOLOGY

Topical flagellin protects the injured corneas from Pseudomonas aeruginosa infection

(2010) Ashok Kumar et al.   MICROBES AND INFECTION

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Reviews for Immune Privilege in the Year 2010: Immune Privilege and Infection

(2010) Linda D. Hazlett et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

Detection of Bacterial Endosymbionts in Clinical Acanthamoeba Isolates

(2010) Alfonso Iovieno et al.   OPHTHALMOLOGY

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

(2010) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Roles for Dectin-1 and TLR4 in the Pathogenesis of Aspergillus fumigatus Keratitis

(2010) Sixto M. Leal et al.   PLoS Pathogens

Increased Resistance of Contact Lens-Related Bacterial Biofilms to Antimicrobial Activity of Soft Contact Lens Care Solutions

(2009) Loretta B Szczotka-Flynn et al.   CORNEA

Role of Pseudomonas aeruginosa type III effectors in disease

(2009) Joanne Engel et al.   CURRENT OPINION IN MICROBIOLOGY

Inhibition of Corneal Inflammation by the TLR4 Antagonist Eritoran Tetrasodium (E5564)

(2009) Y. Sun et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

WolbachiaLipoprotein Stimulates Innate and Adaptive Immunity through Toll-like Receptors 2 and 6 to Induce Disease Manifestations of Filariasis

(2009) Joseph D. Turner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -Defensins 2 and 3 Together Promote Resistance to Pseudomonas aeruginosa Keratitis

(2009) M. Wu et al.   JOURNAL OF IMMUNOLOGY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

The type III secretion system of Pseudomonas aeruginosa: infection by injection

(2009) Alan R. Hauser   NATURE REVIEWS MICROBIOLOGY

Development of a Streptococcus pneumoniae Keratitis Model in Mice

(2009) Quincy C. Moore III et al.   OPHTHALMIC RESEARCH

Microbial Biofilms in Ophthalmology and Infectious Disease

(2008) Irmgard Behlau   ARCHIVES OF OPHTHALMOLOGY

Role of lactoferrin in the tear film

(2008) J FLANAGAN et al.   BIOCHIMIE

Lack of MD-2 expression in human corneal epithelial cells is an underlying mechanism of lipopolysaccharide (LPS) unresponsiveness

(2008) Jing Zhang et al.   IMMUNOLOGY AND CELL BIOLOGY

Pseudomonas aeruginosa Induces Membrane Blebs in Epithelial Cells, Which Are Utilized as a Niche for Intracellular Replication and Motility

(2008) A. A. Angus et al.   INFECTION AND IMMUNITY

C-Jun NH2 terminal kinase (JNK) is an essential mediator of Toll-like receptor 2-induced corneal inflammation

(2008) G. Adhikary et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide

(2008) Y. Sun et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Role of Antimicrobial Peptides at the Ocular Surface

(2008) Alison M. McDermott   OPHTHALMIC RESEARCH

Pseudomonas aeruginosa activates caspase 1 through Ipaf

(2008) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models

(2008) L. G. Burdelya et al.   SCIENCE

Noncytotoxic Lytic Granule-Mediated CD8+ T Cell Inhibition of HSV-1 Reactivation from Neuronal Latency

(2008) J. E. Knickelbein et al.   SCIENCE