Diphtheria-toxin based anti-human CCR4 immunotoxin for targeting human CCR4+ cells in vivo

Regulatory T cells in cancer immunotherapy

(2014) Hiroyoshi Nishikawa et al.   CURRENT OPINION IN IMMUNOLOGY

CCR4 and its ligands: from bench to bedside

(2014) O. Yoshie et al.   INTERNATIONAL IMMUNOLOGY

Diphtheria toxin-based bivalent human IL-2 fusion toxin with improved efficacy for targeting human CD25+ cells

(2014) Jaclyn Stromp Peraino et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Distinct Conformations of the Chemokine Receptor CCR4 with Implications for Its Targeting in Allergy

(2014) J. M. Viney et al.   JOURNAL OF IMMUNOLOGY

Diphtheria toxin-based recombinant murine IL-2 fusion toxin for depleting murine regulatory T cells in vivo

(2014) M. Wei et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Targeting CCR4 as an emerging strategy for cancer therapy and vaccines

(2014) Jagadeesh Bayry et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A truncated diphtheria toxin based recombinant porcine CTLA-4 fusion toxin

(2013) Jaclyn Stromp Peraino et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Development of a diphtheria toxin-based recombinant porcine IL-2 fusion toxin for depleting porcine CD25+ cells

(2013) Jaclyn Stromp Peraino et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans

(2013) D. Sugiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Migratory, and not lymphoid-resident, dendritic cells maintain peripheral self-tolerance and prevent autoimmunity via induction of iTreg cells

(2012) C. Vitali et al.   BLOOD

Expression and characterization of recombinant soluble porcine CD3 ectodomain molecules: Mapping the epitope of an anti-porcine CD3 monoclonal antibody 898H2-6-15

(2012) Jaclyn Stromp Peraino et al.   CELLULAR IMMUNOLOGY

Differential Effects of Denileukin Diftitox IL-2 Immunotoxin on NK and Regulatory T Cells in Nonhuman Primates

(2012) Y. Yamada et al.   JOURNAL OF IMMUNOLOGY

Humanization of an Anti-CCR4 Antibody That Kills Cutaneous T-Cell Lymphoma Cells and Abrogates Suppression by T-Regulatory Cells

(2012) D.-K. Chang et al.   MOLECULAR CANCER THERAPEUTICS

Comprehensive analysis of current approaches to inhibit regulatory T cells in cancer

(2012) Helene Pere et al.   OncoImmunology

Development of a Diphtheria Toxin Based Antiporcine CD3 Recombinant Immunotoxin

(2011) Zhirui Wang et al.   BIOCONJUGATE CHEMISTRY

A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens

(2011) H. Pere et al.   BLOOD

Mechanism of Diphtheria Toxin Catalytic Domain Delivery to the Eukaryotic Cell Cytosol and the Cellular Factors that Directly Participate in the Process

(2011) John R. Murphy   Toxins

Toward the Discovery of Vaccine Adjuvants: Coupling In Silico Screening and In Vitro Analysis of Antagonist Binding to Human and Mouse CCR4 Receptors

(2009) Matthew N. Davies et al.   PLoS One

In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination

(2008) J. Bayry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA