l-Cysteine metabolism and its nutritional implications

Differences in plasma metabolomics between sows fed dl-methionine and its hydroxy analogue reveal a strong association of milk composition and neonatal growth with maternal methionine nutrition

(2015) Xiaoling Zhang et al.   BRITISH JOURNAL OF NUTRITION

N-acetylcysteine and intestinal health a focus on its mechanism of action

(2015) Yongqing Hou   Frontiers in Bioscience-Landmark

Hydrogen peroxide-induced oxidative stress activates NF-κB and Nrf2/Keap1 signals and triggers autophagy in piglets

(2015) Jie Yin et al.   RSC Advances

489 Endogenous H2S Produced in Prevertebral Sympathetic Ganglia Predominantly by Cse in Neurons and Glia Cells Modulates Central Cholinergic Synaptic Input

(2015) Lei Sha et al.   GASTROENTEROLOGY

Effects of randomized supplementation of methionine or alanine on cysteine and glutathione production during the early phase of treatment of children with edematous malnutrition

(2014) Curtis O Green et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate

(2014) Halina Jurkowska et al.   AMINO ACIDS

Changes in plasma amino acid profiles, growth performance and intestinal antioxidant capacity of piglets following increased consumption of methionine as its hydroxy analogue

(2014) Hao Li et al.   BRITISH JOURNAL OF NUTRITION

l-cysteine suppresses ghrelin and reduces appetite in rodents and humans

(2014) A K McGavigan et al.   INTERNATIONAL JOURNAL OF OBESITY

Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington’s disease

(2014) Bindu D. Paul et al.   NATURE

Effects of N-acetyl cysteine on lipid levels and on leukocyte and platelet count in rats after splenectomy

(2014) M Sit et al.   Nigerian Journal of Clinical Practice

Serum Amino Acids Profile and the Beneficial Effects of L-Arginine or L-Glutamine Supplementation in Dextran Sulfate Sodium Colitis

(2014) Wenkai Ren et al.   PLoS One

Hydrogen Sulfide Offers Neuroprotection on Traumatic Brain Injury in Parallel with Reduced Apoptosis and Autophagy in Mice

(2014) Mingyang Zhang et al.   PLoS One

Glutathione and mitochondria

(2014) Vicent Ribas et al.   Frontiers in Pharmacology

Functional amino acids in nutrition and health

(2013) Guoyao Wu   AMINO ACIDS

The Cysteine Dioxgenase Knockout Mouse: Altered Cysteine Metabolism in Nonhepatic Tissues Leads to Excess H2S/HS− Production and Evidence of Pancreatic and Lung Toxicity

(2013) Heather B. Roman et al.   ANTIOXIDANTS & REDOX SIGNALING

Chronic intermittent hypoxia promotes expression of 3-mercaptopyruvate sulfurtransferase in adult rat medulla oblongata

(2013) Mingqiang Li et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Oxidative stress suppresses the cellular bioenergetic effect of the 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway

(2013) Katalin Módis et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hydrogen sulfide is produced by cystathionine γ-lyase at the steady-state low intracellular Ca2+ concentrations

(2013) Yoshinori Mikami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DietaryL-Cysteine Improves the Antioxidative Potential and Lipid Metabolism in Rats Fed a Normal Diet

(2013) Seulki LEE et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Dietary N-acetylcysteine supplementation alleviates liver injury in lipopolysaccharide-challenged piglets

(2013) Dan Yi et al.   BRITISH JOURNAL OF NUTRITION

Long-term cysteine fortification impacts cysteine/glutathione homeostasis and food intake in ageing rats

(2013) Karine Vidal et al.   EUROPEAN JOURNAL OF NUTRITION

Molecular identification and cellular localization of a potential transport system involved in cystine/cysteine uptake in human lenses

(2013) Julie C. Lim et al.   EXPERIMENTAL EYE RESEARCH

Glutathione defense mechanism in liver injury: Insights from animal models

(2013) Y. Chen et al.   FOOD AND CHEMICAL TOXICOLOGY

Birth oxidative stress and the development of an antioxidant system in newborn piglets

(2013) J. Yin et al.   FREE RADICAL RESEARCH

Development of an antioxidant system after early weaning in piglets2

(2013) J. Yin et al.   JOURNAL OF ANIMAL SCIENCE

Structure and Kinetic Analysis of H2S Production by Human Mercaptopyruvate Sulfurtransferase

(2013) Pramod Kumar Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Increasing Glutathione With Cysteine and Glycine Supplementation on Mitochondrial Fuel Oxidation, Insulin Sensitivity, and Body Composition in Older HIV-Infected Patients

(2013) Dan Nguyen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metal vs. chalcogen competition in the catalytic mechanism of cysteine dioxygenase

(2013) Xin Che et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Specific amino acids inhibit food intake via the area postrema or vagal afferents

(2013) Josua Jordi et al.   JOURNAL OF PHYSIOLOGY-LONDON

P41

(2013) Adrienne L. King et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

P06 CSE/H2S rescues impaired arteriogenesis in mouse hind limb ischemia via IL-16 dependant monocyte recruitment and expression of bFGF

(2013) Shyamal C. Bir et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Brain 3-Mercaptopyruvate Sulfurtransferase (3MST): Cellular Localization and Downregulation after Acute Stroke

(2013) Heng Zhao et al.   PLoS One

l-Cysteine Efflux in Erythrocytes As A Function of Human Age: Correlation with Reduced Glutathione and Total Anti-Oxidant Potential

(2013) Prabhanshu Kumar et al.   REJUVENATION RESEARCH

Glutathione redox potential is low and glutathionylated and cysteinylated hemoglobin levels are elevated in maintenance hemodialysis patients

(2013) Khaled Khazim et al.   Translational Research

Arylthioamides as H2S Donors: l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo

(2013) Alma Martelli et al.   ACS Medicinal Chemistry Letters

A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells

(2013) Norihiro Shibuya et al.   Nature Communications

Plasma Free H 2 S Levels are Elevated in Patients With Cardiovascular Disease

(2013) Elvis A. Peter et al.   Journal of the American Heart Association

Production of Hydrogen Sulfide from D-Cysteine and Its Therapeutic Potential

(2013) Norihiro Shibuya et al.   Frontiers in Endocrinology

Methionine requirement of the enterally fed term infant in the first month of life in the presence of cysteine

(2012) Lisha Huang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia

(2012) Utpal Sen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Gustatory sensation of l- and d-amino acids in humans

(2012) Misako Kawai et al.   AMINO ACIDS

N-acetylcysteine reduces inflammation in the small intestine by regulating redox, EGF and TLR4 signaling

(2012) Yongqing Hou et al.   AMINO ACIDS

H2S: A “Double face” molecule in health and disease

(2012) Alessandra di Masi et al.   BIOFACTORS

Dietary supplementation with N-acetyl cysteine, α-tocopherol and α-lipoic acid reduces the extent of oxidative stress and proinflammatory state in aged rat brain

(2012) Ishita Guha Thakurta et al.   BIOGERONTOLOGY

L-Cysteine supplementation as an adjuvant therapy for type-2 diabetes

(2012) Sushil K. Jain   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Endogenous CSE/H2S system mediates TNF-α-induced insulin resistance in 3T3-L1 adipocytes

(2012) Ci-You Huang et al.   CELL BIOCHEMISTRY AND FUNCTION

Effect of taurine and N-acetylcysteine on methionine restriction-mediated adiposity resistance

(2012) Amany K. Elshorbagy et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The effect of taurine on cholesterol metabolism

(2012) Wen Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Plasma glutathione of HIV+ patients responded positively and differently to dietary supplementation with cysteine or glutamine

(2012) Maria Dorotéia Borges-Santos et al.   NUTRITION

Mechanism of the protective action of taurine in toxin and drug induced organ pathophysiology and diabetic complications: a review

(2012) Joydeep Das et al.   Food & Function

Dietary cysteine is used more efficiently by children with severe acute malnutrition with edema compared with those without edema

(2011) Asha Badaloo et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation

(2011) R. V. Sekhar et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The transsulfuration pathway: a source of cysteine for glutathione in astrocytes

(2011) Gethin J. McBean   AMINO ACIDS

Modulation of neuronal glutathione synthesis by EAAC1 and its interacting protein GTRAP3-18

(2011) Koji Aoyama et al.   AMINO ACIDS

The oxidative stress-inducible cystine/glutamate antiporter, system x c − : cystine supplier and beyond

(2011) Marcus Conrad et al.   AMINO ACIDS

Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide

(2011) Yoshinori Mikami et al.   BIOCHEMICAL JOURNAL

First-pass splanchnic metabolism of dietary cysteine in weanling pigs1

(2011) C. Bauchart-Thevret et al.   JOURNAL OF ANIMAL SCIENCE

H2S Donor, S-Propargyl-Cysteine, Increases CSE in SGC-7901 and Cancer-Induced Mice: Evidence for a Novel Anti-Cancer Effect of Endogenous H2S?

(2011) Kaium MA et al.   PLoS One

Oxidative stress increases SNAT1 expression and stimulates cysteine uptake in freshly isolated rat cardiomyocytes

(2010) Nicola King et al.   AMINO ACIDS

Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine

(2010) R. V. Sekhar et al.   DIABETES CARE

Cysteine/cystine redox signaling in cardiovascular disease

(2010) Young-Mi Go et al.   FREE RADICAL BIOLOGY AND MEDICINE

Rapid Activation of Glutamate Cysteine Ligase following Oxidative Stress

(2010) Cecile M. Krejsa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Biochemistry of Hydrogen Sulfide

(2010) Omer Kabil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur

(2010) Martha H. Stipanuk et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase

(2010) Amany K. Elshorbagy et al.   JOURNAL OF LIPID RESEARCH

Postprandial Cysteine/Cystine Redox Potential in Human Plasma Varies with Meal Content of Sulfur Amino Acids

(2010) Youngja Park et al.   JOURNAL OF NUTRITION

Iron(II)-ThiolateS-Oxygenation by O2: Synthetic Models of Cysteine Dioxygenase

(2010) Yunbo Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dietary sulfur amino acid effects on fasting plasma cysteine/cystine redox potential in humans

(2010) Dean P. Jones et al.   NUTRITION

Formulation of a Medical Food Cocktail for Alzheimer's Disease: Beneficial Effects on Cognition and Neuropathology in a Mouse Model of the Disease

(2010) Anna Parachikova et al.   PLoS One

Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase

(2010) J. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nervous control of circulation – The role of gasotransmitters, NO, CO, and H2S

(2009) Kenneth R. Olson et al.   ACTA HISTOCHEMICA

Sulfur amino acid deficiency upregulates intestinal methionine cycle activity and suppresses epithelial growth in neonatal pigs

(2009) Caroline Bauchart-Thevret et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Amino acids and gaseous signaling

(2009) Xilong Li et al.   AMINO ACIDS

L-cysteine supplementation attenuates local inflammation and restores gut homeostasis in a porcine model of colitis

(2009) C.J. Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

l-Cysteine supplementation lowers blood glucose, glycated hemoglobin, CRP, MCP-1, and oxidative stress and inhibits NF-κB activation in the livers of Zucker diabetic rats

(2009) Sushil K. Jain et al.   FREE RADICAL BIOLOGY AND MEDICINE

H2S Biogenesis by Human Cystathionine γ-Lyase Leads to the Novel Sulfur Metabolites Lanthionine and Homolanthionine and Is Responsive to the Grade of Hyperhomocysteinemia

(2009) Taurai Chiku et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Open-labeled pilot study of cysteine-rich whey protein isolate supplementation for nonalcoholic steatohepatitis patients

(2009) Taned Chitapanarux et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels

(2008) M. H. Stipanuk et al.   AMINO ACIDS

L-Cysteine Down-Regulates SREBP-1c-Regulated Lipogenic Enzymes Expression via Glutathione in HepG2 Cells

(2008) Anja Bettzieche et al.   ANNALS OF NUTRITION AND METABOLISM

3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain

(2008) Norihiro Shibuya et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen sulfide protects astrocytes against H2O2-induced neural injury via enhancing glutamate uptake

(2008) Ming Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The role and regulation of Trxl, a cytosolic thioredoxin in Schizosaccharomyces pombe

(2008) Ji-Yoon Song et al.   JOURNAL OF MICROBIOLOGY

3T3-L1 Adipocytes and Rat Adipose Tissue Have a High Capacity for Taurine Synthesis by the Cysteine Dioxygenase/Cysteinesulfinate Decarboxylase and Cysteamine Dioxygenase Pathways

(2008) Iori Ueki et al.   JOURNAL OF NUTRITION

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine  -Lyase

(2008) G. Yang et al.   SCIENCE