α-Synuclein Over-Expression Induces Increased Iron Accumulation and Redistribution in Iron-Exposed Neurons

AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo

(2015) Kim-Ann Saal et al.   NEUROBIOLOGY OF DISEASE

Correlative organelle fluorescence microscopy and synchrotron X-ray chemical element imaging in single cells

(2014) Stéphane Roudeau et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Divalent metal ions enhance DOPAL-induced oligomerization of alpha-synuclein

(2014) Yunden Jinsmaa et al.   NEUROSCIENCE LETTERS

ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS

(2014) J C Koch et al.   Cell Death & Disease

The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca2+ levels to α-synuclein toxicity in Parkinson’s disease models

(2012) S Büttner et al.   CELL DEATH AND DIFFERENTIATION

Copper, zinc and iron in neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases)

(2012) Henryk Kozlowski et al.   COORDINATION CHEMISTRY REVIEWS

Golgi fragmentation is Rab and SNARE dependent in cellular models of Parkinson’s disease

(2012) Wilson O. Rendón et al.   HISTOCHEMISTRY AND CELL BIOLOGY

X-ray fluorescence analysis of iron and manganese distribution in primary dopaminergic neurons

(2012) Tanja Dučić et al.   JOURNAL OF NEUROCHEMISTRY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

α-Synuclein expression is modulated at the translational level by iron

(2012) Fabia Febbraro et al.   NEUROREPORT

Role of Alpha-Synuclein Protein Levels in Mitochondrial Morphology and Cell Survival in Cell Lines

(2012) Min Zhu et al.   PLoS One

Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons

(2011) Grit Taschenberger et al.   ACTA NEUROPATHOLOGICA

Epidemiology and etiology of Parkinson’s disease: a review of the evidence

(2011) Karin Wirdefeldt et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Plasmids containing NRSE/RE1 sites enhance neurite outgrowth of retinal ganglion cells via sequestration of REST independent of NRSE dsRNA expression

(2011) Jan C. Koch et al.   FEBS Journal

α-Synuclein increases U251 cells vulnerability to hydrogen peroxide by disrupting calcium homeostasis

(2011) Zhengxin Ying et al.   JOURNAL OF NEURAL TRANSMISSION

Parkinson's disease and α-synuclein expression

(2011) Michael J. Devine et al.   MOVEMENT DISORDERS

Alpha-Synuclein Is a Cellular Ferrireductase

(2011) Paul Davies et al.   PLoS One

Alpha-synuclein aggregation is involved in the toxicity induced by ferric iron to SK-N-SH neuroblastoma cells

(2010) Qing He et al.   JOURNAL OF NEURAL TRANSMISSION

TGF-β 1 enhances neurite outgrowth via regulation of proteasome function and EFABP

(2010) Johanna Knöferle et al.   NEUROBIOLOGY OF DISEASE

The Guelph PIXE software package IV

(2010) J.L. Campbell et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dose- and time-dependent α-synuclein aggregation induced by ferric iron in SK-N-SH cells

(2010) Wen-Jing Li et al.   Neuroscience Bulletin

Metal binding to alpha-synuclein peptides and its contribution to toxicity

(2009) David R. Brown   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Converse modulation of toxic α-synuclein oligomers in living cells by N′-benzylidene-benzohydrazide derivates and ferric iron

(2009) Andreas S. Hillmer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells

(2009) Mordhwaj S. Parihar et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Binding of α-synuclein with Fe(III) and with Fe(II) and biological implications of the resultant complexes

(2009) Yong Peng et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Bio-metals imaging and speciation in cells using proton and synchrotron radiation X-ray microspectroscopy

(2009) R. Ortega et al.   Journal of the Royal Society Interface

Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons

(2009) Eugene V. Mosharov et al.   NEURON

Quantitative micro-analysis of metal ions in subcellular compartments of cultured dopaminergic cells by combination of three ion beam techniques

(2008) A. Carmona et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Nano-imaging of trace metals by synchrotron X-ray fluorescence into dopaminergic single cells and neurite-like processes

(2008) Asuncion Carmona et al.   JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY

Single Particle Characterization of Iron-induced Pore-forming α-Synuclein Oligomers

(2008) Marcus Kostka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GATA transcription factors directly regulate the Parkinson's disease-linked gene  -synuclein

(2008) C. R. Scherzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA