The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca2+ levels to α-synuclein toxicity in Parkinson’s disease models

Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants

(2012) Jason P. Covy et al.   JOURNAL OF NEUROSCIENCE RESEARCH

N-acetylcysteine Protects against Apoptosis through Modulation of Group I Metabotropic Glutamate Receptor Activity

(2012) Lili Sun et al.   PLoS One

Mitochondria, calcium, and endoplasmic reticulum stress in Parkinson's disease

(2011) Tito Calì et al.   BIOFACTORS

Acidic calcium stores of Saccharomyces cerevisiae

(2011) Kyle W. Cunningham   CELL CALCIUM

Regulation of Intracellular Manganese Homeostasis by Kufor-Rakeb Syndrome-associated ATP13A2 Protein

(2011) Jieqiong Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New Regulators of a High Affinity Ca2+Influx System Revealed through a Genome-wide Screen in Yeast

(2011) D. Christian Martin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Synuclein, leucine-rich repeat kinase-2, and manganese in the pathogenesis of parkinson disease

(2011) Jason P. Covy et al.   NEUROTOXICOLOGY

N-acetylcysteine prevents loss of dopaminergic neurons in theEAAC1−/−mouse

(2010) Ari E. Berman et al.   ANNALS OF NEUROLOGY

Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1

(2010) Frits Kamp et al.   EMBO JOURNAL

A Syd-1 homologue regulates pre- and postsynaptic maturation inDrosophila

(2010) David Owald et al.   JOURNAL OF CELL BIOLOGY

Metals, oxidative stress and neurodegenerative disorders

(2010) Klaudia Jomova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Modelling neurodegeneration in Saccharomyces cerevisiae: why cook with baker's yeast?

(2010) Vikram Khurana et al.   NATURE REVIEWS NEUROSCIENCE

Oral N-Acetyl-Cysteine Attenuates Loss of Dopaminergic Terminals in α-Synuclein Overexpressing Mice

(2010) Joanne Clark et al.   PLoS One

Calcium homeostasis and signaling in yeast cells and cardiac myocytes

(2009) Jiangjun Cui et al.   FEMS YEAST RESEARCH

The Divalent Metal Transporter Homologues SMF-1/2 Mediate Dopamine Neuron Sensitivity in Caenorhabditis elegans Models of Manganism and Parkinson Disease

(2009) Raja Settivari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Synuclein modulation of Ca2+signaling in human neuroblastoma (SH-SY5Y) cells

(2009) Nishani T. Hettiarachchi et al.   JOURNAL OF NEUROCHEMISTRY

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

(2009) Aaron D Gitler et al.   NATURE GENETICS

Phosphorylation, lipid raft interaction and traffic of α-synuclein in a yeast model for Parkinson

(2008) Piotr Zabrocki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Quinone and oxyradical scavenging properties of N-acetylcysteine prevent dopamine mediated inhibition of Na+, K+-ATPase and mitochondrial electron transport chain activity in rat brain: Implications in the neuroprotective therapy of Parkinson's disease

(2008) Maria B. Bagh et al.   FREE RADICAL RESEARCH

Calcium ions in neuronal degeneration

(2008) Urszula Wojda et al.   IUBMB LIFE

Functional Mitochondria Are Required for α-Synuclein Toxicity in Aging Yeast

(2008) Sabrina Büttner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity

(2008) Liyan Qiao et al.   Molecular Brain

Calcium(II) selectively induces α-synuclein annular oligomers via interaction with the C-terminal domain

(2004) Rachel Lowe et al.   PROTEIN SCIENCE