Notch3-specific inhibition using siRNA knockdown or GSI sensitizes paclitaxel-resistant ovarian cancer cells

Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice

(2015) Kirsten C. Verhein et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

NOTCH3 Gene Polymorphism is Associated With the Prognosis of Gliomas in Chinese Patients

(2015) Zhipeng Shen et al.   MEDICINE

Temporal and Embryonic Lineage-Dependent Regulation of Human Vascular SMC Development by NOTCH3

(2015) Alessandra Granata et al.   STEM CELLS AND DEVELOPMENT

Cerebral Cavernous Malformation-1 Protein Controls DLL4-Notch3 Signaling Between the Endothelium and Pericytes

(2015) G. B. Schulz et al.   STROKE

Notch3 functions as a regulator of cell self-renewal by interacting with the β-catenin pathway in hepatocellular carcinoma

(2015) Qingyu Zhang et al.   Oncotarget

Clinical Significance of Cerebral Microbleeds Locations in CADASIL with R544C NOTCH3 Mutation

(2015) Jung Seok Lee et al.   PLoS One

Activation of NOTCH1 or NOTCH3 Signaling Skews Human Airway Basal Cell Differentiation toward a Secretory Pathway

(2015) Kazunori Gomi et al.   PLoS One

TLR2 enhances ovarian cancer stem cell self-renewal and promotes tumor repair and recurrence

(2013) Ilana Chefetz et al.   CELL CYCLE

Notch inhibitors for cancer treatment

(2013) Ingrid Espinoza et al.   PHARMACOLOGY & THERAPEUTICS

Targeting Notch signaling pathway in cancer: Clinical development advances and challenges

(2013) Naoko Takebe et al.   PHARMACOLOGY & THERAPEUTICS

Notch3 Overexpression as Potential Therapeutic Target in Advanced Stage Chemoresistant Ovarian Cancer

(2012) Mohammed Tanjimur Rahman et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

A Comparative Method for Both Discrete and Continuous Characters Using the Threshold Model

(2012) Joseph Felsenstein   AMERICAN NATURALIST

Cancerous ovarian stem cells: Obscure targets for therapy but relevant to chemoresistance

(2012) Nuzhat Ahmed et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy

(2012) S. M. McAuliffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of BMI1, a Stem Cell Factor, in Cancer Recurrence and Chemoresistance: Preclinical and Clinical Evidences

(2012) Hifzur Rahman Siddique et al.   STEM CELLS

Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence

(2011) K Pandya et al.   BRITISH JOURNAL OF CANCER

Aldehyde Dehydrogenase in Combination with CD133 Defines Angiogenic Ovarian Cancer Stem Cells That Portend Poor Patient Survival

(2011) I. A. Silva et al.   CANCER RESEARCH

Common Cancer Stem Cell Gene Variants Predict Colon Cancer Recurrence

(2011) A. Gerger et al.   CLINICAL CANCER RESEARCH

Phase I Trial of MK-0752 in Children With Refractory CNS Malignancies: A Pediatric Brain Tumor Consortium Study

(2011) Maryam Fouladi et al.   JOURNAL OF CLINICAL ONCOLOGY

Notch3 Overexpression Is Related to the Recurrence of Ovarian Cancer and Confers Resistance to Carboplatin

(2010) Joon Tae Park et al.   AMERICAN JOURNAL OF PATHOLOGY

Down-regulation of Notch1 by gamma-secretase inhibition contributes to cell growth inhibition and apoptosis in ovarian cancer cells A2780

(2010) Mingyi Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prognostic significance of Notch 3 gene expression in ovarian serous carcinoma

(2010) Sang G. Jung et al.   CANCER SCIENCE

Notch3 Is Critical for Proper Angiogenesis and Mural Cell Investment

(2010) Hua Liu et al.   CIRCULATION RESEARCH

Transcription Inhibition by Platinum−DNA Cross-Links in Live Mammalian Cells

(2010) Wee Han Ang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Musashi1 regulates breast tumor cell proliferation and is a prognostic indicator of poor survival

(2010) Xiao-Yang Wang et al.   Molecular Cancer

Evaluation of Selective  -Secretase Inhibitor PF-03084014 for Its Antitumor Efficacy and Gastrointestinal Safety to Guide Optimal Clinical Trial Design

(2010) P. Wei et al.   MOLECULAR CANCER THERAPEUTICS

Down-regulation of the Notch pathway mediated by a γ-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia

(2009) J Tammam et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Activated Notch1 Signal Pathway Is Associated with Gastric Cancer Progression through Cyclooxygenase-2

(2009) T.-S. Yeh et al.   CANCER RESEARCH

The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis

(2009) Rui Benedito et al.   CELL

The postoperative brain tumour stem cell (BTSC) niche and cancer recurrence

(2008) Jian-Min Liu et al.   ADVANCES IN THERAPY

Jagged-1 and Notch3 Juxtacrine Loop Regulates Ovarian Tumor Growth and Adhesion

(2008) J.-H. Choi et al.   CANCER RESEARCH