Activation of NOTCH1 or NOTCH3 Signaling Skews Human Airway Basal Cell Differentiation toward a Secretory Pathway

Submersion and Hypoxia Inhibit Ciliated Cell Differentiation in a Notch-Dependent Manner

(2014) Benjamin J. Gerovac et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Dynamic Changes in Intracellular ROS Levels Regulate Airway Basal Stem Cell Homeostasis through Nrf2-Dependent Notch Signaling

(2014) Manash K. Paul et al.   Cell Stem Cell

Airway-Specific Inducible Transgene Expression Using Aerosolized Doxycycline

(2013) Purushothama Rao Tata et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Jagged1 is the major regulator of notch-dependent cell fate in proximal airways

(2013) Shubing Zhang et al.   DEVELOPMENTAL DYNAMICS

Notch signaling at a glance

(2013) K. Hori et al.   JOURNAL OF CELL SCIENCE

Tissue-Dependent Consequences of Apc Inactivation on Proliferation and Differentiation of Ciliated Cell Progenitors via Wnt and Notch Signaling

(2013) Aimin Li et al.   PLoS One

EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype

(2013) R. Shaykhiev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity

(2013) Matthew S Walters et al.   RESPIRATORY RESEARCH

Fine-tuning of the intracellular canonical Notch signaling pathway

(2012) Tilman Borggrefe et al.   CELL CYCLE

Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells

(2012) M. Morimoto et al.   DEVELOPMENT

Pathobiologic Mechanisms of Chronic Obstructive Pulmonary Disease

(2012) Anthony Tam et al.   MEDICAL CLINICS OF NORTH AMERICA

Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways

(2012) A. Guha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NOTCH1 Is Required for Regeneration of Clara Cells During Repair of Airway Injury

(2012) Yiming Xing et al.   STEM CELLS

The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways

(2012) O. Boucherat et al.   Biology Open

Distal Airway Stem Cells Yield Alveoli In Vitro and during Lung Regeneration following H1N1 Influenza Infection

(2011) Pooja A. Kumar et al.   CELL

Notch-Dependent Differentiation of Adult Airway Basal Stem Cells

(2011) Jason R. Rock et al.   Cell Stem Cell

Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development

(2011) Po-Nien Tsao et al.   DEVELOPMENT

Notch signaling: simplicity in design, versatility in function

(2011) E. R. Andersson et al.   DEVELOPMENT

Erratum: Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway

(2011) Brice Marcet et al.   NATURE CELL BIOLOGY

Small-Airway Obstruction and Emphysema in Chronic Obstructive Pulmonary Disease

(2011) John E. McDonough et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Human Airway Epithelial Basal Cell Transcriptome

(2011) Neil R. Hackett et al.   PLoS One

Biologic Phenotyping of the Human Small Airway Epithelial Response to Cigarette Smoking

(2011) Ann E. Tilley et al.   PLoS One

The airway epithelium: more than just a structural barrier

(2011) Anthony Tam et al.   Therapeutic Advances in Respiratory Disease

Smoking-related Small Airway Disease—A Review and Update

(2010) Mary Beth Beasley   ADVANCES IN ANATOMIC PATHOLOGY

Tracheal Basal Cells

(2010) Brook B. Cole et al.   AMERICAN JOURNAL OF PATHOLOGY

Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling

(2010) J. R. Rock et al.   Disease Models & Mechanisms

Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate

(2010) M. Morimoto et al.   JOURNAL OF CELL SCIENCE

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Small Airway Mucous Metaplasia and Inflammation in Chronic Obstructive Pulmonary Disease

(2009) Victor Kim et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Notch signaling controls the balance of ciliated and secretory cell fates in developing airways

(2009) P.-N. Tsao et al.   DEVELOPMENT

Notch signaling promotes airway mucous metaplasia and inhibits alveolar development

(2009) J. S. Guseh et al.   DEVELOPMENT

Basal cells as stem cells of the mouse trachea and human airway epithelium

(2009) J. R. Rock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Down-regulation of the Notch Pathway in Human Airway Epithelium in Association with Smoking and Chronic Obstructive Pulmonary Disease

(2008) Ann E. Tilley et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Characterization of Side Population Cells from Human Airway Epithelium

(2008) Tillie-Louise Hackett et al.   STEM CELLS