Phytochemical regulation of the tumor suppressive microRNA, miR-34a, by p53-dependent and independent responses in human breast cancer cells

Hyaluronic acid-chitosan nanoparticles for co-delivery of MiR-34a and doxorubicin in therapy against triple negative breast cancer

(2014) Xiongwei Deng et al.   BIOMATERIALS

Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells and inhibits cyclin-dependent kinase-4 promoter activity and expression by disrupting nuclear factor-κB transcriptional signaling

(2013) Kalvin Q. Tran et al.   ANTI-CANCER DRUGS

Anti-cancer activity of DHA on gastric cancer—an in vitro and in vivo study

(2013) Haijun Sun et al.   TUMOR BIOLOGY

Artemisinin inhibits gastric cancer cell proliferation through upregulation of p53

(2013) Hong-Tao Zhang et al.   TUMOR BIOLOGY

MicroRNA-34a Modulates Chemosensitivity of Breast Cancer Cells to Adriamycin by Targeting Notch1

(2012) Xiu-juan Li et al.   ARCHIVES OF MEDICAL RESEARCH

MiR-34a inhibits proliferation and migration of breast cancer through down-regulation of Bcl-2 and SIRT1

(2012) Laisheng Li et al.   CLINICAL AND EXPERIMENTAL MEDICINE

The microcosmos of cancer

(2012) Amaia Lujambio et al.   NATURE

Antiproliferative effects of artemisinin on human breast cancer cells requires the downregulated expression of the E2F1 transcription factor and loss of E2F1-target cell cycle genes

(2011) Antony S. Tin et al.   ANTI-CANCER DRUGS

Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA

(2011) Mark Mackiewicz et al.   BREAST CANCER RESEARCH AND TREATMENT

Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling

(2011) Ida Aronchik et al.   MOLECULAR CARCINOGENESIS

MiR-34a Expression Has an Effect for Lower Risk of Metastasis and Associates with Expression Patterns Predicting Clinical Outcome in Breast Cancer

(2011) Hanna Peurala et al.   PLoS One

Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas

(2011) Markus Vogt et al.   VIRCHOWS ARCHIV

Chemoprevention of Cigarette Smoke-Induced Alterations of MicroRNA Expression in Rat Lungs

(2010) A. Izzotti et al.   Cancer Prevention Research

Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

(2010) Dmitri Lodygin et al.   CELL CYCLE

Implication of microRNAs in drug resistance for designing novel cancer therapy

(2010) Fazlul H. Sarkar et al.   DRUG RESISTANCE UPDATES

The antimalarial agent artesunate possesses anticancer properties that can be enhanced by combination strategies

(2010) Wai M. Liu et al.   INTERNATIONAL JOURNAL OF CANCER

Anticancer activity of botanical compounds in ancient fermented beverages (Review)

(2010) McGovern   INTERNATIONAL JOURNAL OF ONCOLOGY

Pharmacogenomic Identification of c-Myc/Max-Regulated Genes Associated with Cytotoxicity of Artesunate towards Human Colon, Ovarian and Lung Cancer Cell Lines

(2010) Serkan Sertel et al.   MOLECULES

Regulation of microRNAs by Natural Agents: An Emerging Field in Chemoprevention and Chemotherapy Research

(2010) Yiwei Li et al.   PHARMACEUTICAL RESEARCH

Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol

(2009) T. Melkamu et al.   CARCINOGENESIS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC

(2009) N R Christoffersen et al.   CELL DEATH AND DIFFERENTIATION

The miR-34 family in cancer and apoptosis

(2009) H Hermeking   CELL DEATH AND DIFFERENTIATION

Anticancer activities of artemisinin and its bioactive derivatives

(2009) Gary L. Firestone et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Minireview: Modulation of Hormone Receptor Signaling by Dietary Anticancer Indoles

(2009) Gary L. Firestone et al.   MOLECULAR ENDOCRINOLOGY

TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use

(2009) M. Olivier et al.   Cold Spring Harbor Perspectives in Biology

Indole-3-carbinol as a chemopreventive and anti-cancer agent

(2008) Jing-Ru Weng et al.   CANCER LETTERS

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Artemisinin Blocks Prostate Cancer Growth and Cell Cycle Progression by Disrupting Sp1 Interactions with the Cyclin-dependent Kinase-4 (CDK4) Promoter and Inhibiting CDK4 Gene Expression

(2008) Jamin A. Willoughby et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS