Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling

Direct Inhibition of Elastase Activity by Indole-3-Carbinol Triggers a CD40-TRAF Regulatory Cascade That Disrupts NF-κB Transcriptional Activity in Human Breast Cancer Cells

(2010) Ida Aronchik et al.   CANCER RESEARCH

1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells

(2010) Hanh H. Nguyen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Anticancer Properties of Indole Compounds: Mechanism of Apoptosis Induction and Role in Chemotherapy

(2010) Aamir Ahmad et al.   CURRENT DRUG TARGETS

Indole-3-Carbinol Triggers Aryl Hydrocarbon Receptor-dependent Estrogen Receptor (ER)α Protein Degradation in Breast Cancer Cells Disrupting an ERα-GATA3 Transcriptional Cross-Regulatory Loop

(2010) Crystal N. Marconett et al.   MOLECULAR BIOLOGY OF THE CELL

Dietary Chemopreventive Phytochemicals: Too Little or Too Much?

(2009) E. P. Moiseeva et al.   Cancer Prevention Research

Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol

(2009) T. Melkamu et al.   CARCINOGENESIS

NF-κB Inhibition through Proteasome Inhibition or IKKβ Blockade Increases the Susceptibility of Melanoma Cells to Cytostatic Treatment through Distinct Pathways

(2009) Katharina Amschler et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Minireview: Modulation of Hormone Receptor Signaling by Dietary Anticancer Indoles

(2009) Gary L. Firestone et al.   MOLECULAR ENDOCRINOLOGY

Anti-adult T-cell leukemia/lymphoma effects of indole-3-carbinol

(2009) Yoshiaki Machijima et al.   Retrovirology

Cancer chemotherapy with indole-3-carbinol, bis(3′-indolyl)methane and synthetic analogs

(2008) Stephen Safe et al.   CANCER LETTERS

DEVD-NucView488: a novel class of enzyme substrates for real-time detection of caspase-3 activity in live cells

(2008) Hui Cen et al.   FASEB JOURNAL

Indole-3-carbinol inhibits MDA-MB-231 breast cancer cell motility and induces stress fibers and focal adhesion formation by activation of Rho kinase activity

(2008) Christine T. Brew et al.   INTERNATIONAL JOURNAL OF CANCER

The dietary phytochemical indole-3-carbinol is a natural elastase enzymatic inhibitor that disrupts cyclin E protein processing

(2008) H. H. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N-Alkoxy derivatization of indole-3-carbinol increases the efficacy of the G1 cell cycle arrest and of I3C-specific regulation of cell cycle gene transcription and activity in human breast cancer cells

(2007) Sarah M. Jump et al.   BIOCHEMICAL PHARMACOLOGY