Article
Health Care Sciences & Services
Andreea-Daniela Meca, Adina Turcu-Stiolica, Elena Camelia Stanciulescu, Ana Marina Andrei, Floarea Mimi Nitu, Ileana Monica Banita, Marius Matei, Catalina-Gabriela Pisoschi
Summary: Tuberculosis is a global infectious disease with a complex pathogenesis. Recent studies have shown changes in oxidative parameters and antioxidant status in TB patients after anti-tubercular therapy. Monitoring TB based on oxidative stress and antioxidant status may be beneficial in disease management and progression.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Mi Yang, Xiaofei Zhou, Xi Tan, Xincheng Huang, Lu Yuan, Zipeng Zhang, Yan Yang, Min Xu, Ying Wan, Zezhi Li
Summary: Alcohol dependence leads to oxidative stress in the body, as evident from the changes observed in the levels of oxidative stress biomarkers. This meta-analysis highlights the decreased activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx) enzymes and lower levels of albumin, along with increased levels of malondialdehyde (MDA), vitamin B12, homocysteine, and bilirubin in patients with alcohol dependence.
Review
Biochemistry & Molecular Biology
Angelo Zinellu, Arduino A. Mangoni
Summary: The systematic review and meta-analysis showed that statins significantly increased the concentrations of glutathione peroxidase and superoxide dismutase in the blood, indicating an antioxidant effect. However, the impact on catalase was minimal.
Article
Environmental Sciences
Joanna Maria Drozdz-Afelt, Beata Barbara Koim-Puchowska, Piotr Kaminski
Summary: The study aimed to analyze antioxidant enzyme activity and malondialdehyde concentration in prostate cancer, finding a significant decrease in superoxide dismutase activity, which may be due to a deficiency in the antioxidant defense system.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Review
Medicine, General & Internal
Ting-ting Li, Hong-ying Wang, Hui Zhang, Ping-ping Zhang, Ming-chen Zhang, Hai-yang Feng, Xiao-yong Duan, Wen-bo Liu, Xiao-wen Wang, Zhong-guang Sun
Summary: This meta-analysis systematically evaluated the effects of breathing exercises on oxidative stress biomarkers in humans and provided evidence for clinical application. The results showed that participants who performed breathing exercises had greater changes in the biomarkers, suggesting that these can be used to evaluate oxidative stress after respiratory interventions.
FRONTIERS IN MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Sahar Golabi, Sheyda Ghasemi, Maryam Adelipour, Reza Bagheri, Katsuhiko Suzuki, Alexei Wong, Maryam Seyedtabib, Mahshid Naghashpour
Summary: This study compared the antioxidant and inflammatory responses between COVID-19 outpatients and healthy individuals, finding higher concentrations of superoxide dismutase (SOD) and glutathione peroxidase (GPx) in COVID-19 patients. These results suggest that targeting oxidative stress in COVID-19 could be a promising therapeutic approach.
Review
Biochemistry & Molecular Biology
Maria Carmina Pau, Arduino Aleksander Mangoni, Elisabetta Zinellu, Gianfranco Pintus, Ciriaco Carru, Alessandro Giuseppe Fois, Pietro Pirina, Angelo Zinellu
Summary: The study found that whole blood SOD concentrations were significantly lower in patients with obstructive sleep apnoea, while serum/plasma SOD concentrations did not show a significant difference. This suggests an impaired antioxidant defence in OSA patients.
Article
Biochemistry & Molecular Biology
Rumyana Simeonova, Mariyana Atanasova, Georgi Stavrakov, Irena Philipova, Irini Doytchinova
Summary: This study investigated the antioxidant and cholinesterase inhibitory potential of a novel galantamine-curcumin hybrid (4b). The results showed that 4b increased antioxidant enzyme activity, reduced oxidative stress-induced neurotoxicity, and decreased brain tissue damage and cholinesterase activity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Slavica Borkovic-Mitic, Aleksandar Stojsavljevic, Ljiljana Vujotic, Sinisa Matic, Bojan Mitic, Dragan Manojlovic, Sladan Pavlovic
Summary: This study examined the impact of oxidative stress on patients with benign and malignant brain tumors, finding that tumor cells showed altered cell metabolism and an adaptive response to increased oxidative stress. The study identified significant differences in antioxidant system parameters and key trace elements between control, benign, and malignant brain tissues. Furthermore, principal component analysis effectively distinguished between benign and malignant tissue, with correlative relationships linked to selenium in benign tumors and copper in malignant tumors.
SCIENTIFIC REPORTS
(2021)
Article
Environmental Sciences
Chao Xing, Jinyu Li, Hongli Yuan, Jinshui Yang
Summary: This study investigated the response mechanism of microalgae under heat and cold stress. The results showed that heat stress led to a significant increase in reactive oxygen species, while cold stress initially increased and then decreased reactive oxygen species. Key elements such as superoxide dismutase and nitric oxide increased under heat stress, while proline and heat shock transcriptional factor increased under cold stress. This study provides a basis for understanding the response mechanism of microalgae to temperature stress and improving their tolerance to temperature stress.
ENVIRONMENTAL RESEARCH
(2022)
Review
Biochemistry & Molecular Biology
Mengli Zheng, Yating Liu, Guanfeng Zhang, Zhikang Yang, Weiwei Xu, Qinghua Chen
Summary: Superoxide dismutase (SOD) is an enzyme that can respond to cellular oxidative stress and has shown effectiveness in anti-tumor, anti-radiation, and anti-aging studies. This research summarizes the types, biological functions, and applications of SODs, and highlights the challenges of membrane permeability and enzyme persistence.
Article
Chemistry, Multidisciplinary
Gwang-Bum Im, Young Geon Kim, Tae Yong Yoo, Yeong Hwan Kim, Kang Kim, Jiyu Hyun, Min Soh, Taeghwan Hyeon, Suk Ho Bhang
Summary: Copper-deposited ceria nanoparticles (CuCe NPs) exhibit enhanced antioxidant effects and therapeutic performance through the upregulation of specific biological factors, scavenging reactive oxygen species, and promoting anti-inflammation and M2 polarization of macrophages. In ischemic vascular diseases, CuCe NPs afford increased perfusion and alleviate tissue damage.
ADVANCED MATERIALS
(2023)
Article
Biotechnology & Applied Microbiology
Pengfei Zhai, Yinyan Ma, Huan Xu, Ling Lu
Summary: This study demonstrates that MtmA is involved in responding to oxidative stress by activating mitochondrial SodB activity in A. fumigatus. MtmA, especially for the first Mito-carr domain, is essential for colony growth by regulating cellular Zn2+ equilibrium and responses to oxidative stress. This study reveals the vital and unique role of the MtmA protein in pathogenic fungi, suggesting its potential as a target for antifungal drugs.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Namrata Singh, Somanathapura K. NaveenKumar, Motika Geethika, Govindasamy Mugesh
Summary: The study demonstrates that CeVO4 nanozyme can substitute the function of SOD1 and SOD2 in neuronal cells even when the natural enzymes are down-regulated. The nanozyme prevents mitochondrial damage by regulating superoxide levels and restores physiological levels of anti-apoptotic proteins. Additionally, it effectively prevents mitochondrial depolarization and improves cellular ATP levels under oxidative stress.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Medicine, Research & Experimental
Ken-Ichiro Tanaka, Mikako Shimoda, Maho Kubota, Ayaka Takafuji, Masahiro Kawahara, Tohru Mizushima
Summary: Lecithinized superoxide dismutase (PCSOD) effectively ameliorates renal ischemia/reperfusion (I/R) injury by inhibiting ROS production, reducing markers of renal damage and fibrosis, and preventing the transition from acute kidney injury (AKI) to chronic kidney disease (CKD). This suggests that PCSOD could be a promising therapeutic agent for I/R-induced renal injury.
Article
Neurosciences
Jesus Martinez-Samano, Alan Flores-Poblano, Leticia Verdugo-Diaz, Marco Antonio Juarez-Oropeza, Patricia V. Torres-Duran
Article
Chemistry, Medicinal
Marco Antonio Hernandez-Lepe, Jose Alberto Lopez-Diaz, Marco Antonio Juarez-Oropeza, Rosa Patricia Hernandez-Torres, Abraham Wall-Medrano, Arnulfo Ramos-Jimenez
Article
Chemistry, Medicinal
Jesus Martinez-Samano, Adriana Torres-Montes de Oca, Oscar Ivan Luqueno-Bocardo, Patricia V. Torres-Duran, Marco A. Juarez-Oropeza
Article
Gastroenterology & Hepatology
Jose L. Martinez, Ilka Bosco-Garate, Luis Manuel Souza-Gallardo, Jose D. Mendez, Marco A. Juarez-Oropeza, Ruben Roman-Ramos, Eduardo Ferat-Osorio
JOURNAL OF GASTROINTESTINAL SURGERY
(2020)
Article
Biochemistry & Molecular Biology
Cristobal Flores-Castillo, Maria Luna-Luna, Elizabeth Carreon-Torres, Victoria Lopez-Olmos, Sara Frias, Marco Antonio Juarez-Oropeza, Martha Franco, Jose Manuel Fragoso, Gilberto Vargas-Alarcon, Oscar Perez-Mendez
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2019)
Article
Chemistry, Medicinal
Marco Antonio Hernandez-Lepe, Abraham Wall-Medrano, Jose Alberto Lopez-Diaz, Marco Antonio Juarez-Oropeza, Oscar Ivan Luqueno-Bocardo, Rosa Patricia Hernandez-Torres, Arnulfo Ramos-Jimenez
Article
Psychology, Biological
Edith Ramirez-Rosas, Pedro Nicolas Velazquez, Leticia Verdugo-Diaz, Elia Martha Perez-Armendariz, Marco Antonio Juarez-Oropeza, Maria Cristina Paredes-Carbajal
PHYSIOLOGY & BEHAVIOR
(2019)
Article
Pharmacology & Pharmacy
Carlos Hernandez-Diaz, Marco Antonio Juarez-Oropeza, Dieter Mascher, Natalia Pavon, Ignacio Regla, Maria Cristina Paredes-Carbajal
CANNABIS AND CANNABINOID RESEARCH
(2020)
Meeting Abstract
Sport Sciences
Blanca Ursula Ortega-Castillo, Jose Pedraza-Chaverri, Marco A. Juarez-Oropeza, Abraham Wall-Medrano, Laura A. De la Rosa, Jose A. Lopez-Diaz, Arnulfo Ramos-Jimenez
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2020)
Article
Social Sciences, Interdisciplinary
Arnulfo Ramos-Jimenez, Rosa Patricia Hernandez-Torres, Abraham Wall-Medrano, Marco Antonio Juarez-Oropeza
Meeting Abstract
Sport Sciences
Marco A. Hernandez-Lepe, Abraham Wall-Medrano, Jose A. Lopez-Diaz, Marco A. Juarez-Oropeza, Rosa P. Hernandez-Torres, Arnulfo Ramos-Jimenez
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2018)
Article
Microbiology
Lucero Romero Aguilar, Juan Pablo Pardo, Monica Montero Lomeli, Oscar Ivan Luqueno Bocardo, Marco A. Juarez Oropeza, Guadalupe Guerra Sanchez
ARCHIVES OF MICROBIOLOGY
(2017)
Article
Medical Laboratory Technology
Armando Quintanilla-Cantu, Paola Pena-de-la-Sancha, Cristobal Flores-Castillo, Ana Maria Mejia-Dominguez, Rosalinda Posadas-Sanchez, Nonanzit Perez-Hernandez, Rocio Bautista-Perez, Reyna Esmeralda Enriquez-Calderon, Marco Antonio Juarez-Oropeza, Jose Manuel Fragoso, Gilberto Vargas-Alarcon, Oscar Perez-Mendez
CLINICA CHIMICA ACTA
(2017)